Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dianna L. Hynds"'
Publikováno v:
Molecular Neurobiology. 57:2220-2231
Mevalonate pathway inhibitors have been extensively studied for their roles in cholesterol depletion and for inhibiting the prenylation and activation of various proteins. Inhibition of protein prenylation has potential therapeutic uses against neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7a0413c2a0f6afe54827b28afc8b08
https://doi.org/10.1007/s12035-020-01870-0
https://doi.org/10.1007/s12035-020-01870-0
Autor:
DiAnna L Hynds
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 7, Pp 1032-1033 (2015)
Externí odkaz:
https://doaj.org/article/b02897e2ba204f569aababcdf4c7a04f
Publikováno v:
Molecular neurobiology. 57(5)
Mevalonate pathway inhibitors have been extensively studied for their roles in cholesterol depletion and for inhibiting the prenylation and activation of various proteins. Inhibition of protein prenylation has potential therapeutic uses against neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::486287b249f1340c168a9daf94d4b089
https://pubmed.ncbi.nlm.nih.gov/31989383
https://pubmed.ncbi.nlm.nih.gov/31989383
Autor:
Jordan A. McConnell, Jairus M. Reddy, Brian W. Beck, Cristina P. Reddy, DiAnna L. Hynds, Filsy Samuel
Publikováno v:
Cellular Signalling. 27:630-637
Rac1 is an important regulator of axon extension, cell migration and actin reorganization. Like all Rho guanine triphosphatases (GTPases), Rac1 is targeted to the membrane by the addition of a geranylgeranyl moiety, an action thought to result in Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304d30f642cda1684862e85135cb80c1
https://doi.org/10.1016/j.cellsig.2014.11.033
https://doi.org/10.1016/j.cellsig.2014.11.033
Emerging evidence suggests that long-term exposure of insulin-secreting pancreatic β-cells to hyperglycemic (HG; glucotoxic) conditions promotes oxidative stress, which, in turn, leads to stress kinase activation, mitochondrial dysfunction, loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cf2b9e12d5c723961720821f98d3dc
https://europepmc.org/articles/PMC5643241/
https://europepmc.org/articles/PMC5643241/
Autor:
Santaneel Ghosh, Somesree GhoshMitra, Jai Dahiya, DiAnna L. Hynds, Zhibing Hu, David R. Diercks, Tong Cai, James A. Roberts, Nathaniel Mills
Publikováno v:
Polymers, Vol 3, Iss 3, Pp 1243-1254 (2011)
Polymers
Volume 3
Issue 3
Pages 1243-1254
Polymers
Volume 3
Issue 3
Pages 1243-1254
Quantum Dots (QDs) have become an interesting subject of study for labeling and drug delivery in biomedical research due to their unique responses to external stimuli. In this paper, the biological effects of a novel hydrogel based QD nano-structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49f507aebaa38e120e01639e3637b9f
https://doi.org/10.3390/polym3031243
https://doi.org/10.3390/polym3031243
Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells
Autor:
Nathaniel Mills, Manal Elfakhani, Rajasekhar Katuru, Clay King, Dibyendu Dutta, DiAnna L. Hynds, Nicolle V Fernandes, Huanbiao Mo
Publikováno v:
Experimental Biology and Medicine. 236:604-613
The diterpene geranylgeraniol (all trans-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-ol) suppresses the growth of human liver, lung, ovary, pancreas, colon, stomach and blood tumors with undefined mechanisms. We evaluated the growth-suppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a06552530d2fb9c8461d2179c6b563
https://doi.org/10.1258/ebm.2011.010379
https://doi.org/10.1258/ebm.2011.010379
Publikováno v:
Procedia - Social and Behavioral Sciences. 8:458-464
Based on the Bureau of Labour and Statistics (BLS) employment projections, more and more technology-driven jobs will be created and, therefore, demand for highly-skilled technologically-trained professionals will increase. What is being done in the U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e310748bc150be6e4d30413ac3b988
https://doi.org/10.1016/j.sbspro.2010.12.063
https://doi.org/10.1016/j.sbspro.2010.12.063
Autor:
Diane M. Snow, DiAnna L. Hynds
Publikováno v:
Journal of Neuroscience Methods. 121:53-64
Axon outgrowth and guidance are differentially promoted or inhibited by specific extracellular matrix (ECM) molecules. The effects of these molecules can be examined by culturing neuronal explants on patterned substrata consisting of alternating stri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505fd546f38e091bd83981fa98e0deb1
https://doi.org/10.1016/s0165-0270(02)00231-5
https://doi.org/10.1016/s0165-0270(02)00231-5
Publikováno v:
Neuroscience. 114:731-744
Gangliosides and extracellular matrix molecules influence neurite outgrowth, but the combinatorial effects of these endogenous agents on outgrowth are unclear. Exogenous gangliosides inhibit neurite outgrowth from SH-SY5Y cells stimulated with platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1da2ca59335aa1e4161f58df29f85a6
https://doi.org/10.1016/s0306-4522(02)00302-0
https://doi.org/10.1016/s0306-4522(02)00302-0