Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diane W Dynia"'
Autor:
Nicolas Cornière, R Brent Thomson, Stéphanie Thauvin, Bruno O Villoutreix, Sophie Karp, Diane W Dynia, Sarah Burlein, Lennart Brinkmann, Alaa Badreddine, Aurélie Dechaume, Mehdi Derhourhi, Emmanuelle Durand, Emmanuel Vaillant, Philippe Froguel, Régine Chambrey, Peter S Aronson, Amélie Bonnefond, Dominique Eladari
Publikováno v:
Journal of Medical Genetics. 59:1035-1043
BackgroundNephrolithiasis (NL) is a complex multifactorial disease affecting up to 10%–20% of the human population and causing a significant burden on public health systems worldwide. It results from a combination of environmental and genetic facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6b64342b58674b35aa84ff0d5dd64
https://doi.org/10.1136/jmedgenet-2021-108256
https://doi.org/10.1136/jmedgenet-2021-108256
Autor:
Diane W. Dynia, Ian Gross, Christine M. Wilson, Clifford W. Bogue, Hemaxi Vasavada, Harris C. Jacobs
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 266:L448-L454
Hox genes are sequence-specific DNA transcription factors, which are important in embryonic development and are expressed in a number of fetal tissues, including the lung. Additionally, retinoic acid (RA) has been shown to modulate Hox gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d1029cb1d945bee743e2ee926f4b29
https://doi.org/10.1152/ajplung.1994.266.4.l448
https://doi.org/10.1152/ajplung.1994.266.4.l448
Publikováno v:
American journal of physiology. Renal physiology. 293(1)
Direct phosphorylation of sodium hydrogen exchanger type 3 (NHE3) is a well-established physiological phenomenon; however, the exact role of NHE3 phosphorylation in its regulation remains unclear. The objective of this study was to evaluate whether N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a752531dcc7f5f4f6fcd56ca420538f1
https://pubmed.ncbi.nlm.nih.gov/17409282
https://pubmed.ncbi.nlm.nih.gov/17409282
Publikováno v:
The American journal of physiology. 271(5 Pt 1)
Retinoic acid has both early or immediate (within hours) and late (after days) effects on gene expression. We studied the early effects of retinoic acid on the surfactant protein (SP) genes. Exposure of fetal rat lung explants to all trans-retinoic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80306acaed49e9fd7757e840eea3baf
https://pubmed.ncbi.nlm.nih.gov/8944731
https://pubmed.ncbi.nlm.nih.gov/8944731
Publikováno v:
The American journal of physiology. 267(1 Pt 1)
We examined the effects of Na butyrate, a known regulator of gene expression, on surfactant protein mRNA concentration, transcription, and degradation. Exposure of explants of 18-day fetal rat lung to Na butyrate resulted in a decrease in surfactant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c817ea06b23422c5ff5b6e4d19eced0f
https://pubmed.ncbi.nlm.nih.gov/8048547
https://pubmed.ncbi.nlm.nih.gov/8048547
Publikováno v:
The American journal of physiology. 259(6 Pt 1)
We have previously shown that dexamethasone, triiodothyronine (T3) and dibutyryl adenosine 3',5'-cyclic monophosphate (cAMP) stimulate phosphatidylcholine (PC) synthesis in fetal rat lung explants in culture. There are also additive interactions betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2731ef5e47af26fedbe6049036290ae0
https://pubmed.ncbi.nlm.nih.gov/2175559
https://pubmed.ncbi.nlm.nih.gov/2175559
Publikováno v:
Pediatric Research. 41:45-45
Homeobox transcription factors influence the expression of multiple genes, thereby regulating patterns of differentiation and cell fate. The Hoxa5, b5 and Hex homeobox genes are actively expressed in fetal rat lung, but little is known of their regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4208ebc328741fad9e22c2cbe02d6368
https://doi.org/10.1203/00006450-199704001-00276
https://doi.org/10.1203/00006450-199704001-00276
Publikováno v:
Pediatric Research. 39:57-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4364ca891b127e0923e3d13256931636
https://doi.org/10.1203/00006450-199604001-00349
https://doi.org/10.1203/00006450-199604001-00349
Publikováno v:
Pediatric Research. 25:239-244
To determine whether the initiation of fetal lung surfactant phospholipid production and the activation of the gene for the 35-kD surfactant-associated protein are dependent on circulating corticosteroids, we cultured dexamethasone-responsive explant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de83f679c2ef8a806a2ca2c3dafb78a0
https://doi.org/10.1203/00006450-198903000-00004
https://doi.org/10.1203/00006450-198903000-00004
Publikováno v:
Biochimica et biophysica acta. 930(1)
We have developed a relatively simple and reproducible method for the isolation and culture of both differentiated and undifferentiated type II cells from fetal rat lung. The technique involves an initial period of explant culture in serum and hormon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a536d90b5918709588c12045e00cf73
https://pubmed.ncbi.nlm.nih.gov/3620509
https://pubmed.ncbi.nlm.nih.gov/3620509