Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Diane V Lefley"'
Autor:
Chryso Kanthou, Gabi U Dachs, Diane V Lefley, Andrew J Steele, Claudia Coralli-Foxon, Sheila Harris, Olga Greco, Sofia A Dos Santos, Constantino C Reyes-Aldasoro, William R English, Gillian M Tozer
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104015 (2014)
Vascular endothelial growth factor-A (VEGF) is produced by most cancer cells as multiple isoforms, which display distinct biological activities. VEGF plays an undisputed role in tumour growth, vascularisation and metastasis; nevertheless the function
Externí odkaz:
https://doaj.org/article/2f15655a60294b4ea0c0503622288433
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Summary of the effects of IL-1B on breast cancer progression to metastasis and growth in the bone microenvironment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c966886aa3515add73124f35ba96fdd4
https://doi.org/10.1158/1078-0432.22472744.v1
https://doi.org/10.1158/1078-0432.22472744.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Suppression of IL-1 signalling affects bone integrity and vasculature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c325261461851db8ab242f40b164f0c7
https://doi.org/10.1158/1078-0432.22472750.v1
https://doi.org/10.1158/1078-0432.22472750.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44d71f01e6bbe78530a36fc9eede0dc
https://doi.org/10.1158/1078-0432.22472741.v1
https://doi.org/10.1158/1078-0432.22472741.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Effects of IL-1B on osteoclast and osteoblast activity in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b007b54acb30669ee466909235f57
https://doi.org/10.1158/1078-0432.22472747.v1
https://doi.org/10.1158/1078-0432.22472747.v1
Autor:
Gillian M. Tozer, Chryso Kanthou, Scott K. Lyons, Jack E. Hurrell, Karina Bingham, Yu-Chin Lee, Mohit Dhingra, Diane V. Lefley, Matthew Fisher, Sarah Jane Lunt, William R. English
Elevated plasma concentrations of soluble VEGFA isoforms are associated with poor prognosis in parallel with improved response to treatment with the anti-VEGFA antibody bevacizumab. To uncover the underlying mechanism to these observations, we admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aaba787cfa8fbaa921a7be20ca3fdb1
https://doi.org/10.1158/0008-5472.c.6508532.v1
https://doi.org/10.1158/0008-5472.c.6508532.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Incubation with high concentrations of exogenous IL-1B modestly increases tumour cell migration and invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba561472369534842ef8e89064113d
https://doi.org/10.1158/1078-0432.22472756.v1
https://doi.org/10.1158/1078-0432.22472756.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
In vivo model of spontaneous human breast cancer metastasis to human bone implants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e4ee90c1febd67029eac311f790e5
https://doi.org/10.1158/1078-0432.22472765.v1
https://doi.org/10.1158/1078-0432.22472765.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Purpose:Breast cancer bone metastases are incurable, highlighting the need for new therapeutic targets. After colonizing bone, breast cancer cells remain dormant, until signals from the microenvironment stimulate outgrowth into overt metastases. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129d3ad9037fd9bc83853742bf10c0d
https://doi.org/10.1158/1078-0432.c.6528317.v1
https://doi.org/10.1158/1078-0432.c.6528317.v1
Autor:
Gillian M. Tozer, Chryso Kanthou, Scott K. Lyons, Jack E. Hurrell, Karina Bingham, Yu-Chin Lee, Mohit Dhingra, Diane V. Lefley, Matthew Fisher, Sarah Jane Lunt, William R. English
The supplementary methods file contains additional detailed information regarding: 1. The production of cell lines stably expressing luciferase. 2. Mouse strains and pre-clinical models of tumor growth and metastasis. 3. Acquisition and analysis of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709da946d9d38146143bb30503defe37
https://doi.org/10.1158/0008-5472.22412831
https://doi.org/10.1158/0008-5472.22412831