Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Diane Soeffker"'
Autor:
Mary Harvey, Michael C. Blanco, Suzanne Greiner, Mark J. Federspiel, James Krempski, Corey Raffel, Diane Soeffker, Paula J. Zollman, Rae Myers, Steven E. Shelton, Evanthia Galanis, Timothy J. Kaufmann
Publikováno v:
Human Gene Therapy. 19:690-698
Gliomas have a dismal prognosis, with the median survival of patients with the most common histology, glioblastoma multiforme, being only 12-15 months. Development of novel therapeutic agents is urgently needed. We have previously demonstrated that o
Autor:
Mary Harvey, Mark J. Federspiel, Rae Myers, Kah-Whye Peng, Diane Soeffker, Suzanne Greiner, Elizabeth M. Hadac, Anderson Bd, Stephen J. Russell
Publikováno v:
Cancer gene therapy. 13(8)
Because of their ability to replicate, the dose-response relationships of oncolytic viruses cannot easily be predicted. To better understand the pharmacokinetics of virotherapy in relation to viral dose and schedule, we administered MV-CEA intraperit
Autor:
Mark J. Federspiel, Katalin G. Abraham, Kah Whye Peng, Rae Myers, Shmuel Rozenblatt, Stephen J. Russell, Marie Frenzke, Alan Shaw, Suzanne Greiner, Diane Soeffker, Mary Harvey
Publikováno v:
Cancer gene therapy. 12(7)
Oncolytic viruses are promising cytoreductive agents for cancer treatment but extensive human testing will be required before they are made commercially available. Here, we investigated the oncolytic potential of two commercially available live atten
Autor:
Kah Whye Peng, Mark J. Federspiel, Mary Harvey, Rae Myers, Roberto Cattaneo, Evanthia Galanis, Suzanne Greiner, Stephen J. Russell, Marie Frenzke, Diane Soeffker
Publikováno v:
Human gene therapy. 14(16)
In support of a proposed phase I clinical trial, we studied the biodistribution of virus-infected cells after intraperitoneal administration of oncolytic measles viruses to alpha/beta interferon-defective mice expressing human CD46 with human-like ti
Autor:
Peng Kah-Whye, Galanis Evanthia, Diane Soeffker, Suzanne Greiner, Rae Myers, Steven E. Shelton, Goerss J. Stephan, Mary Harvey, Paula J. Zollman, Russell J. Stephen, James Krempski, Raffel Corey, Kaufmann J. Timothy, Federspiel J. Mark
Publikováno v:
Molecular Therapy. 13:S113
Novel therapies for patients with recurrent gliomas are urgently needed, given their dismal prognosis,. Oncolytic measles virus strains derived from the Edmonston vaccine lineage are an attractive option for glioma therapy, because of their significa
Publikováno v:
Molecular Therapy. 9:S108
Attenuated measles viruses are promising oncolytic agents that will soon be tested in phase I clinical trials. However, we predict that their therapeutic potential will be limited by the antiviral immune response of the host. Initial delivery of the
Autor:
Rae Myers, Mary Harvey, Timothy J. Kaufmann, Suzanne M. Greiner, James W. Krempski, Corey Raffel, Steven E. Shelton, Diane Soeffker, Paula Zollman, Mark J. Federspiel, Michael Blanco, Evanthia Galanis
Publikováno v:
Human Gene Therapy; Jul2008, Vol. 19 Issue 7, p690-698, 9p
Autor:
Koning, Ludi1,2, Charlton, Michael R.3, Pas, Suzan D.4, Heimbach, Julie K.2, Osterhaus, Albert D. M. E.4, Watt, Kymberly D.2, Janssen, Harry L. A.5, de Knegt, Robert J.1, van der Eijk, Annemiek A.4 a.vandereijk@erasmusmc.nl
Publikováno v:
BMC Infectious Diseases. 9/2/2015, Vol. 15 Issue 1, p1-6. 6p. 1 Diagram, 2 Charts.
Autor:
Myers, R. M., Greiner, S. M., Harvey, M. E., Griesmann, G., Kuffel, M. J., Buhrow, S. A., Reid, J. M., Federspiel, M., Ames, M. M., Dingli, D., Schweikart, K., Welch, A., Dispenzieri, A., Peng, K.-W., Russell, S. J.
Publikováno v:
Clinical Pharmacology & Therapeutics; Dec2007, Vol. 82 Issue 6, p700-710, 11p, 3 Diagrams, 3 Charts, 2 Graphs
Autor:
Vernino, Steven, Lennon, Vanda A.
Publikováno v:
Annals of Neurology; 2000, Vol. 47 Issue 3, p297-305, 9p