Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diane P. Swanlund"'
Autor:
Gurnit Kaur, Elaine M Leslie, Holly Tillman, William M Lee, Diane P Swanlund, Constantine J Karvellas, US Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139299 (2015)
Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH). Ophthalmic acid (OA) is an analogue of GSH in which cysteine is replaced
Externí odkaz:
https://doaj.org/article/b3eb308a2ca34edcbfa0766ac36c8a32
Autor:
Olga Antipova, Kelly L. Summers, Natalia V. Dolgova, Olena Ponomarenko, Ingrid J. Pickering, Janet R. Zhou, Graham N. George, Elaine M. Leslie, Diane P. Swanlund, Gurnit Kaur
Publikováno v:
Chemico-biological interactions. 327
Hundreds of millions of people worldwide are exposed to unacceptable levels of carcinogenic inorganic arsenic. Animal models have shown that selenium and arsenic are mutually protective through the formation and elimination of the seleno-bis(S-glutat
Autor:
Graham N. George, Angela Casini, Diane P. Swanlund, Kelly L. Summers, Joseph R. Casey, Emmanuelle Cordat, Kamran Shekh, Warda Javed, Ingrid J. Pickering, Margot N. Wenzel, Gurnit Kaur, Elaine M. Leslie, Olena Ponomarenko, Janet R. Zhou
Publikováno v:
Biochemical Pharmacology. 180:114141
Over 200 million people worldwide are exposed to the human carcinogen, arsenic, in contaminated drinking water. In laboratory animals, arsenic and the essential trace element, selenium, can undergo mutual detoxification through the formation of the s
Autor:
Kelly L. Summers, Diane P. Swanlund, Angela Casini, Emmanuelle Cordat, Ingrid J. Pickering, Graham N. George, Michael Hu, Olena Ponomarenko, Elaine M. Leslie, Warda Javed, Joseph R. Casey, Margot N. Wenzel, Gurnit Kaur
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Kevin E. Weigl, Elaine M. Leslie, Caley B. Shukalek, Rodney K. Rousseau, Diane P. Swanlund, Vanessa Marensi, Susan P.C. Cole
Publikováno v:
Molecular pharmacology. 90(2)
The ATP-binding cassette (ABC) transporter multidrug resistance protein 1 (MRP1/ ABCC1 ) is responsible for the cellular export of a chemically diverse array of xenobiotics and endogenous compounds. Arsenic, a human carcinogen, is a high-affinity MRP