Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Diane P. Kost"'
1
Patterns of Alpha-1-Adrenergic Receptor Expression in Regenerating and Neoplastic Hepatic Tissue
Autor: Chi-Ru Lee, Marie C. DeFrances, GeorgeK. Michalopoulos, Diane P. Kost
Publikováno v: Pathobiology. 60:303-308
As norepinephrine is a potent hepatocyte comitogen through binding to the alpha 1-adrenergic receptor, we have examined mRNA levels of the alpha 1a- and alpha 1b-adrenergic receptor subtypes in normal and regenerating rat hepatocytes as well as in se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5726342130cd863bee0ecd387a7d366
https://doi.org/10.1159/000163740
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3
Effect of 2% dimethyl sulfoxide on the mitogenic properties of epidermal growth factor and hepatocyte growth factor in primary hepatocyte culture
Autor: George K. Michalopoulos, Diane P. Kost
Publikováno v: Journal of Cellular Physiology. 147:274-280
Two percent dimethyl sulfoxide (DMSO) reversibly inhibited DNA synthesis in primary rat hepatocyte cultures maintained with epidermal growth factor (EGF) or hepatocyte growth factor (HGF). These data suggest that, in vitro, DMSO is a non-specific inh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2792edf0a9a1754b20df904e992bd1
https://doi.org/10.1002/jcp.1041470212
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4
Expression of Hepatocyte Growth Factor mRNA in regenerating rat liver after partial hepatectomy
Autor: Diane P. Kost, Pamela Lindroos, George K. Michalopoulos, Marie C. DeFrances, Reza Zarnegar
Publikováno v: Biochemical and Biophysical Research Communications. 177:559-565
Hepatocyte Growth Factor (HGF) is a potent complete mitogen for primary cultures of hepatocytes in vitro. There is strong evidence that this novel growth factor may mediate hepatocyte regeneration after liver damage. We have shown previously that the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ea03cfbb7b3e75b67aa2d05344f2fe
https://doi.org/10.1016/0006-291x(91)92020-k
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5
Effect of epidermal growth factor on the expression of protooncogenes c-myc and c-Ha-ras in short-term primary hepatocyte culture
Autor: George K. Michalopoulos, Diane P. Kost
Publikováno v: Journal of Cellular Physiology. 144:122-127
We have characterized the effect of the hepatomitogen epidermal growth factor (EGF) on the expression of the cellular protooncogenes c-Ha-ras and c-myc in short-term (48 hours) primary hepatocyte culture. mRNA concentrations of both protooncogenes in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613a4d7f8aa6d467a2e2d5ae119bfd20
https://doi.org/10.1002/jcp.1041440116
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7
Multiple sequential periods of DNA synthesis and quiescence in primary hepatocyte cultures maintained on the DMSO-EGF on/off protocol
Autor: George K. Michalopoulos, Krammie Chan, Diane P. Kost
Publikováno v: Journal of cellular physiology. 141(3)
Repeated periods of DNA synthesis activity (each period consisting of two to three cycles) separated by intervals of quiescence in primary rat hepatocytes can be stimulated by sequential addition and removal of 2% dimethyl sulfoxide (DMSO) in the pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca44ed2c1989423d33b4f4c3859e86
https://pubmed.ncbi.nlm.nih.gov/2592427
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