Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diane P., Bofinger"'
Autor:
Moheswar Sharma, Barbara P. McGarrigle, Jennifer Lewis, James R. Olson, Minoti Sharma, Diane P. Bofinger, David E. Shubert
Publikováno v:
Chemico-Biological Interactions. 146:237-249
Although long-term tamoxifen therapy is associated with increased risk of endometrial cancer, little is known about the ability of endometrial tissue to biotransform tamoxifen to potentially reactive intermediates, capable of forming DNA adducts. The
Autor:
Minoti Sharma, Chad M. Vezina, James R. Olson, David E. Shubert, Moheswar Sharma, Diane P. Bofinger, Kerry J. Rodabaugh, Barbara P. McGarrigle
Publikováno v:
Biochemical and Biophysical Research Communications. 307:157-164
Fresh human endometrial explants were incubated for 24h at 37 degrees C with either tamoxifen (10-100 micro M) or the vehicle (0.1% ethanol). Three metabolites namely, alpha-hydroxytamoxifen, 4-hydroxytamoxifen, and N-desmethyltamoxifen were identifi
Publikováno v:
Experimental Hematology. 30:634-639
Objective Murine erythroblasts infected with the anemia-inducing strain of Friend virus (FVA cells) terminally differentiate to the reticulocyte stage after 48 hours of culture in vitro in response to erythropoietin (EPO). The objective of this study
Autor:
Thomas R. Sutter, Li Feng, Frank D. Stephen, Kevin G. Osteen, James R. Olson, John Love, Theodore G. Costich, Diane P. Bofinger, Ronald E. Batt, Lai-Har Chi, Stephen T. Koury
Publikováno v:
Toxicological Sciences. 62:299-314
Endometriosis is a debilitating disease estimated to affect 10% of reproductive-age women and characterized by the growth of endometrial tissue outside of the uterus. The present study char- acterizes a human endometrial explant culture model for stu
Publikováno v:
Molecular Endocrinology. 5:42-50
The high mobility group protein HMG 14, which is preferentially associated with nucleosomes containing active gene sequences, is phosphorylated on different sites according to the tissue and stimulus being studied. In the thyroid, HMG 14 displays TSH
Autor:
Li Feng, Theodore G. Costich, Diane P. Bofinger, Ronald E. Batt, Stephen T. Koury, Jeff A. Pitt, Barbara D. Abbott, Judy E. Schmid
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 62(2)
Endometriosis is a debilitating disease found in 10-15% of reproductive-age women and is characterized by the presence of endometrial tissue outside of the uterus. The present study characterizes the expression of AhR and ARNT mRNA in a human endomet
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 927:26-33
Previous studies have indicated that thyrotropin may induce general increases in RNA and protein synthesis in calf thyroid tissue slices. In this report, we show that thyrotropin selectively stimulates [ 35 S]methionine incorporation into small numbe
Publikováno v:
Analytical biochemistry. 170(1)
While clear evidence exists for the regulation of the phosphorylation of the very basic high mobility group (HMG) and histone chromatin proteins, the physiological role of their phosphorylation remains poorly understood. Elucidation of these roles ha
Publikováno v:
In Clinical Biochemistry 1993 26(3):165-171