Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Diane N. Ignacio"'
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Akademický článek
Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40
Autor: Diane N. Ignacio, Kimberly D. Mason, Ezra C. Hackett-Morton, Christopher Albanese, Lymor Ringer, William D. Wagner, Paul C. Wang, Michael A. Carducci, Sushant K. Kachhap, Channing J. Paller, Janet Mendonca, Leo Li-Ying Chan, Bo Lin, Diane K. Hartle, Jeffrey E. Green, Collis A. Brown, Tamaro S. Hudson
Publikováno v: Heliyon, Vol 5, Iss 1, Pp e01128- (2019)
Previously we demonstrated that muscadine grape skin extract (MSKE), a natural product, significantly inhibited androgen-responsive prostate cancer cell growth by inducing apoptosis through the targeting of survival pathways. However, the therapeutic
Externí odkaz: https://doaj.org/article/0ec72566e263420685711b900634964a
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2
A literature review of drugs for the treatment of COVID-19
Autor: Shalini Pooransingh, Y Clement, Diane N. Ignacio, Avril Reid, Shurla Sampson-Francis, Satish Jankie, Stanley Giddings, Harold Watson
Publikováno v: Caribbean Medical Journal.
Objectives: To review the published evidence of repurposed drugs, antivirals and biologics for the treatment of COVID-19. Materials and Methods: A literature review was conducted in several databases and research portals. Search terms included COVID-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5899c3e06f25202f0a163372e8111a4
https://doi.org/10.48107/cmj.2020.05.006
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3
Simulating the slow to fast switch in cytochrome c oxidase catalysis by introducing a loop flip near the enzyme's cytochrome c (substrate) binding site
Autor: Trevor Alleyne, Diane N. Ignacio, Michael T. Wilson, Valerie B. Sampson, Damian Ashe
Publikováno v: Biotechnology and Applied Biochemistry. 64:677-685
The mitochondrial enzyme cytochrome c oxidase catalyzes the reduction of molecular oxygen in the critical step of oxidative phosphorylation that links the oxidation of food consumed to ATP production in cells. The enzyme catalyzes the reduction of ox
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e53743a601f9f5fbfa73f0c3418c965
https://doi.org/10.1002/bab.1526
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5
An Evaluation of Treatment Strategies for Head and Neck Cancer in an African American Population
Autor: Fredric A. Lombardo, MG Daniel, MT Serlemitsos-Day, Diane N. Ignacio, T Alleyne, JJ Griffin
Publikováno v: West Indian Medical Journal.
OBJECTIVE This study evaluated treatment strategies for head and neck cancers in a predominantly African American population. METHODS Data were collected utilizing medical records and the tumour registry at the Howard University Hospital. Kaplan-Meie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45f87f4ca35d865dc666f9fc0a4474f
https://doi.org/10.7727/wimj.2013.046
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6
Simulating the slow to fast switch in cytochrome c oxidase catalysis by introducing a loop flip near the enzyme's cytochrome c (substrate) binding site
Autor: Trevor, Alleyne, Diane N, Ignacio, Valerie B, Sampson, Damian, Ashe, Michael, Wilson
Publikováno v: Biotechnology and applied biochemistry. 64(5)
The mitochondrial enzyme cytochrome c oxidase catalyzes the reduction of molecular oxygen in the critical step of oxidative phosphorylation that links the oxidation of food consumed to ATP production in cells. The enzyme catalyzes the reduction of ox
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27786a912046bbc91ca46e1011297b86
https://pubmed.ncbi.nlm.nih.gov/27489224
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8
Confidence in Prescription Writing among Junior Physicians in Trinidad and Tobago
Autor: Y Clement, Patricia Sealy, Diane N. Ignacio
Publikováno v: West Indian Medical Journal.
BACKGROUND A fundamental skill in the practice of medicine is the ability to safely and rationally prescribe drugs. This research aims to estimate the percentage of newly registered medical officers who reported confidence in writing prescriptions. M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc5c4167da08421d7e7cb0ec83784c4
https://doi.org/10.7727/wimj.2014.087
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9
A Bio-computing Analysis of the Resting-to-pulsed Conformational Changes in Cytochrome c Oxidase
Autor: Diane N. Ignacio, Valerie B. Sampson, D Ashe, T Alleyne
Publikováno v: WIMJ Open, Vol 2, Iss 3, Pp 109-114 (2015)
Cytochrome c oxidase (Cox) accepts electrons from its substrate, cytochrome c and passes these to oxygen, which is reduced to water. Kinetic studies show that an active form of the enzyme (pulsed) and a slower form (resting) exists. More efficient in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987f41be4bbdbc17b683af03ea080aab
https://doi.org/10.7727/wimjopen.2015.090
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10
Short Term Effects of Cocoa Consumption on Blood Pressure
Autor: R. Holder, C. Humphrey, K. Rampersad, D. Cozier, L. Pran, R. Haywood, D. Reyes, Diane N. Ignacio, N. Balleram, D Arrindell, S. Bahall, A. Alleyne, T Alleyne
Publikováno v: West Indian Medical Journal.
Hypertension, defined as diastolic pressure ≥ 90 mmHg and systolic pressure ≥ 140 mmHg, is a major cause of morbidity and mortality among black populations globally. Several studies have shown that prolonged consumption of cocoa or cocoa containi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd173b41f63d7f676145491094b6b64
https://doi.org/10.7727/wimj.2013.273
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