Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Diane McMahon-Pratt"'
Autor:
Olivia C. Ihedioha, Haley Q. Marcarian, Anutr Sivakoses, Stephen M. Beverley, Diane McMahon-Pratt, Alfred L. M. Bothwell
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHost-related factors highly regulate the increased circulation of neutrophils during Leishmania infection. Platelet-derived Dickkopf-1 (DKK1) is established as a high-affinity ligand to LRP6. Recently, we demonstrated that DKK1 upregulates
Externí odkaz:
https://doaj.org/article/55f928ce26a24a75b624a2873a7d0b5d
Autor:
Olivia C. Ihedioha, Anutr Sivakoses, Stephen M. Beverley, Diane McMahon-Pratt, Alfred L. M. Bothwell
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPlatelets are rapidly deployed to infection sites and respond to pathogenic molecules via pattern recognition receptors (TLR, NLRP). Dickkopf1 (DKK1) is a quintessential Wnt antagonist produced by a variety of cell types including platelets
Externí odkaz:
https://doaj.org/article/bba3b1ba911e48cc9971cbc868bd1b68
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003820 (2015)
BACKGROUND:Therapeutic response in infectious disease involves host as well as microbial determinants. Because the immune and inflammatory response to Leishmania (Viannia) species defines the outcome of infection and efficacy of treatment, immunomodu
Externí odkaz:
https://doaj.org/article/bb35606e8fcb408fa68356678a3d3bbc
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 91, Iss 1, Pp 37-42 (1996)
Monoclonal antibodies specific for selected species complexes of Leishmania have been employed for the characterization of several representative strains of Leishmania isolated from different hosts and localities in the Americas. In the past 15 years
Externí odkaz:
https://doaj.org/article/d640bf2217824defa0060f04700c25c7
Autor:
Carolina Ramírez, Yira Díaz-Toro, Jair Tellez, Tiago M Castilho, Ricardo Rojas, Nicholas A Ettinger, Irina Tikhonova, Neal D Alexander, Liliana Valderrama, Janet Hager, Mary E Wilson, Aiping Lin, Hongyu Zhao, Nancy G Saravia, Diane McMahon-Pratt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 10, p e1866 (2012)
BACKGROUND:Previous findings indicate that susceptibility to Leishmania (Viannia) panamensis infection of monocyte-derived macrophages from patients and asymptomatically infected individuals were associated with the adaptive immune response and clini
Externí odkaz:
https://doaj.org/article/951668c0529b41399ac320c230d58958
Autor:
Asha Jayakumar, Tiago M Castilho, Esther Park, Karen Goldsmith-Pestana, Jenefer M Blackwell, Diane McMahon-Pratt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1204 (2011)
Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species, indicating a unique interaction with the host. Further, vaccination studies utilizing small an
Externí odkaz:
https://doaj.org/article/6463a2698a0f4010b46fe38f4dca06a9
Autor:
Adriana Navas, Carolina Gallego-Marin, Mariana Rosales-Chilama, Alexandra Cossio, Olga Lucía Fernández, Nancy Gore Saravia, María del Mar Castro, Julieth Murillo, Diane McMahon-Pratt, Maria Adelaida Gomez
Publikováno v:
Infection and Immunity. 88
The immune mechanisms that contribute to the efficacy of treatment of cutaneous leishmaniasis (CL) are not fully understood. The aim of this study was to define immune correlates of the outcome of treatment of CL caused by Leishmania (Viannia) specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac15e9ae2fe8f6dae95a2e4804595326
https://doi.org/10.1128/iai.00764-19
https://doi.org/10.1128/iai.00764-19
Autor:
Adriana, Navas, Olga, Fernández, Carolina, Gallego-Marín, María Del Mar, Castro, Mariana, Rosales-Chilama, Julieth, Murillo, Alexandra, Cossio, Diane, McMahon-Pratt, Nancy Gore, Saravia, María Adelaida, Gómez
Publikováno v:
Infect Immun
The immune mechanisms that contribute to the efficacy of treatment of cutaneous leishmaniasis (CL) are not fully understood. The aim of this study was to define immune correlates of the outcome of treatment of CL caused by Leishmania (Viannia) specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aff88fdc2dfd856aa043838cd2091df3
https://pubmed.ncbi.nlm.nih.gov/31818959
https://pubmed.ncbi.nlm.nih.gov/31818959
Autor:
Diane McMahon-Pratt
Publikováno v:
Immunoepidemiology ISBN: 9783030255527
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e76d1a965304f4f99766be40651fc01
https://doi.org/10.1007/978-3-030-25553-4_15
https://doi.org/10.1007/978-3-030-25553-4_15
Autor:
Eli Chapman, Diane McMahon-Pratt, Arthur L. Horwich, Steven M. Johnson, Nilshad Salim, Najiba Mammadova, Peter G. Schultz, Sanofar Abdeen, Karen Goldsmith-Pestana, Corey M. Summers
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:5247-5253
Trypanosoma brucei are protozoan parasites that cause African sleeping sickness in humans (also known as Human African Trypanosomiasis-HAT). Without treatment, T. brucei infections are fatal. There is an urgent need for new therapeutic strategies as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8af709ab66a4d1b21d4be34ebeab81
https://doi.org/10.1016/j.bmcl.2016.09.051
https://doi.org/10.1016/j.bmcl.2016.09.051