Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Diane Marie Del Valle"'
Autor:
Ishan Paranjpe, Pushkala Jayaraman, Chen-Yang Su, Sirui Zhou, Steven Chen, Ryan Thompson, Diane Marie Del Valle, Ephraim Kenigsberg, Shan Zhao, Suraj Jaladanki, Kumardeep Chaudhary, Steven Ascolillo, Akhil Vaid, Edgar Gonzalez-Kozlova, Justin Kauffman, Arvind Kumar, Manish Paranjpe, Ross O. Hagan, Samir Kamat, Faris F. Gulamali, Hui Xie, Joceyln Harris, Manishkumar Patel, Kimberly Argueta, Craig Batchelor, Kai Nie, Sergio Dellepiane, Leisha Scott, Matthew A. Levin, John Cijiang He, Mayte Suarez-Farinas, Steven G. Coca, Lili Chan, Evren U. Azeloglu, Eric Schadt, Noam Beckmann, Sacha Gnjatic, Miram Merad, Seunghee Kim-Schulze, Brent Richards, Benjamin S. Glicksberg, Alexander W. Charney, Girish N. Nadkarni
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Background Acute kidney injury (AKI) is a known complication of COVID-19 and is associated with an increased risk of in-hospital mortality. Unbiased proteomics using biological specimens can lead to improved risk stratification and discover
Externí odkaz:
https://doaj.org/article/a59378e85e3b46de854114917b9da8cd
Autor:
Chen-Yang Su, Sirui Zhou, Edgar Gonzalez-Kozlova, Guillaume Butler-Laporte, Elsa Brunet-Ratnasingham, Tomoko Nakanishi, Wonseok Jeon, David R. Morrison, Laetitia Laurent, Jonathan Afilalo, Marc Afilalo, Danielle Henry, Yiheng Chen, Julia Carrasco-Zanini, Yossi Farjoun, Maik Pietzner, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Meriem Bouab, Louis Petitjean, Charlotte Guzman, Xiaoqing Xue, Chris Tselios, Branka Vulesevic, Olumide Adeleye, Tala Abdullah, Noor Almamlouk, Yara Moussa, Chantal DeLuca, Naomi Duggan, Erwin Schurr, Nathalie Brassard, Madeleine Durand, Diane Marie Del Valle, Ryan Thompson, Mario A. Cedillo, Eric Schadt, Kai Nie, Nicole W. Simons, Konstantinos Mouskas, Nicolas Zaki, Manishkumar Patel, Hui Xie, Jocelyn Harris, Robert Marvin, Esther Cheng, Kevin Tuballes, Kimberly Argueta, Ieisha Scott, The Mount Sinai COVID-19 Biobank Team, Celia M. T. Greenwood, Clare Paterson, Michael A. Hinterberg, Claudia Langenberg, Vincenzo Forgetta, Joelle Pineau, Vincent Mooser, Thomas Marron, Noam D. Beckmann, Seunghee Kim-schulze, Alexander W. Charney, Sacha Gnjatic, Daniel E. Kaufmann, Miriam Merad, J. Brent Richards
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Predicting COVID-19 severity is difficult, and the biological pathways involved are not fully understood. To approach this problem, we measured 4701 circulating human protein abundances in two independent cohorts totaling 986 individuals. We
Externí odkaz:
https://doaj.org/article/01337ffce78741589c060c556f78383f
Autor:
Weiguang Mao, Clare M Miller, Venugopalan D Nair, Yongchao Ge, Mary Anne S Amper, Antonio Cappuccio, Mary‐Catherine George, Carl W Goforth, Kristy Guevara, Nada Marjanovic, German Nudelman, Hanna Pincas, Irene Ramos, Rachel S G Sealfon, Alessandra Soares‐Schanoski, Sindhu Vangeti, Mital Vasoya, Dawn L Weir, Elena Zaslavsky, Biobank Team, Vanessa Barcessat, Kevin Tuballes, Diane Marie Del Valle, Kai Nie, Hui Xie, Grace Chung, Manishkumar Patel, Jocelyn Harris, Kimberly Argueta, Jacques Fehr, Barr Gruberg, Nicholas Zaki, Seunghee Kim‐Schulze, Sacha Gnjatic, Miriam Merad, Andrew G Letizia, Olga G Troyanskaya, Stuart C Sealfon, Maria Chikina
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-16 (2023)
Abstract DNA methylation comprises a cumulative record of lifetime exposures superimposed on genetically determined markers. Little is known about methylation dynamics in humans following an acute perturbation, such as infection. We characterized the
Externí odkaz:
https://doaj.org/article/4218baf29182454bb07788f37ce0f8e4
Autor:
Noam D. Beckmann, Phillip H. Comella, Esther Cheng, Lauren Lepow, Aviva G. Beckmann, Scott R. Tyler, Konstantinos Mouskas, Nicole W. Simons, Gabriel E. Hoffman, Nancy J. Francoeur, Diane Marie Del Valle, Gurpawan Kang, Anh Do, Emily Moya, Lillian Wilkins, Jessica Le Berichel, Christie Chang, Robert Marvin, Sharlene Calorossi, Alona Lansky, Laura Walker, Nancy Yi, Alex Yu, Jonathan Chung, Matthew Hartnett, Melody Eaton, Sandra Hatem, Hajra Jamal, Alara Akyatan, Alexandra Tabachnikova, Lora E. Liharska, Liam Cotter, Brian Fennessy, Akhil Vaid, Guillermo Barturen, Hardik Shah, Ying-chih Wang, Shwetha Hara Sridhar, Juan Soto, Swaroop Bose, Kent Madrid, Ethan Ellis, Elyze Merzier, Konstantinos Vlachos, Nataly Fishman, Manying Tin, Melissa Smith, Hui Xie, Manishkumar Patel, Kai Nie, Kimberly Argueta, Jocelyn Harris, Neha Karekar, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kevin Tuballes, Ieisha Scott, Arvind Kumar, Suraj Jaladanki, Charuta Agashe, Ryan Thompson, Evan Clark, Bojan Losic, Lauren Peters, The Mount Sinai COVID-19 Biobank Team, Panagiotis Roussos, Jun Zhu, Wenhui Wang, Andrew Kasarskis, Benjamin S. Glicksberg, Girish Nadkarni, Dusan Bogunovic, Cordelia Elaiho, Sandeep Gangadharan, George Ofori-Amanfo, Kasey Alesso-Carra, Kenan Onel, Karen M. Wilson, Carmen Argmann, Supinda Bunyavanich, Marta E. Alarcón-Riquelme, Thomas U. Marron, Adeeb Rahman, Seunghee Kim-Schulze, Sacha Gnjatic, Bruce D. Gelb, Miriam Merad, Robert Sebra, Eric E. Schadt, Alexander W. Charney
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Multisystem inflammatory syndrome in children (MIS-C) onsets in COVID-19 patients with manifestations similar to Kawasaki disease (KD). Here the author probe the peripheral blood transcriptome of MIS-C patients to find signatures related to natural k
Externí odkaz:
https://doaj.org/article/7233a40d610f443eac2e6011b12c9368
Autor:
Guillermo Carbonell, Diane Marie Del Valle, Edgar Gonzalez-Kozlova, Brett Marinelli, Emma Klein, Maria El Homsi, Daniel Stocker, Michael Chung, Adam Bernheim, Nicole W. Simons, Jiani Xiang, Sharon Nirenberg, Patricia Kovatch, Sara Lewis, Miriam Merad, Sacha Gnjatic, Bachir Taouli
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10166- (2022)
Despite extraordinary international efforts to dampen the spread and understand the mechanisms behind SARS-CoV-2 infections, accessible predictive biomarkers directly applicable in the clinic are yet to be discovered. Recent studies have revealed tha
Externí odkaz:
https://doaj.org/article/d38219db71ba4ff3a6109adcf863ca5e
Autor:
Bo Wang, Oliver Van Oekelen, Tarek H. Mouhieddine, Diane Marie Del Valle, Joshua Richter, Hearn Jay Cho, Shambavi Richard, Ajai Chari, Sacha Gnjatic, Miriam Merad, Sundar Jagannath, Samir Parekh, Deepu Madduri
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background The COVID-19 pandemic, caused by SARS-CoV-2 virus, has resulted in over 100,000 deaths in the USA. Our institution has treated over 2000 COVID-19 patients during the pandemic in New York City. The pandemic directly impacted cancer
Externí odkaz:
https://doaj.org/article/2a8a134dee804d76a7bfadb029e72a2b
Autor:
Geoffrey Kelly, Edgar Gonzalez-Kozlova, Manon Herbinet, Diana Handler, Brian T. Lee, Seunghee Kim-Schulze, Bhaskar Upadhyaya, Adeeb Rahman, Sacha Gnjatic, Daniel Geanon, Diane Marie Del Valle, John Leech, Assaf Magen, Miriam Merad, Alexander W. Charney, Ronaldo de Real
Publikováno v:
Cytometry Part A
Cytometry
Cytometry
Mass cytometry (CyTOF) represents one of the most powerful tools in immune phenotyping, allowing high throughput quantification of over 40 parameters at single‐cell resolution. However, wide deployment of CyTOF‐based immune phenotyping studies ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1669fbcc5dca4636485681662a41c5bd
https://doi.org/10.1002/cyto.a.24317
https://doi.org/10.1002/cyto.a.24317
Autor:
Jeffrey S. Jhang, Keith Sigel, Manishkumar Patel, Hsin-Hui Huang, Carlos Cordon-Cardo, Diane Marie Del Valle, Talia H. Swartz, Kevin Tuballes, Judith A. Aberg, David Reich, Adolfo Firpo-Betancourt, Noam D. Beckmann, Sundar Jagannath, Aryeh Stock, Bo Wang, Samir Parekh, Patricia Kovatch, Oliver Van Oekelen, Damodara Rao Mendu, Hui Xie, Adeeb Rahman, Eric E. Schadt, Madhu Mazumdar, Yonit Lavin, Miriam Merad, Marc Feldmann, Alexander W. Charney, Sharon Nirenberg, Thomas U. Marron, Sacha Gnjatic, Deepu Madduri, Seunghee Kim-Schulze
Publikováno v:
Nature Medicine
Nat Med
Nat Med
Several studies have revealed that the hyper-inflammatory response induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease severity and death. However, predictive biomarkers of pathogenic inflammation to he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a321be0bee52eeff424510c812829224
https://doi.org/10.1038/s41591-020-1051-9
https://doi.org/10.1038/s41591-020-1051-9
Autor:
Miriam Merad, Sacha Gnjatic, Patricia Kovatch, Sharon Nirenberg, Jiani Xiang, Diane Marie Del Valle, Edgar Gonzalez-Kozlova, Maria El Homsi, Michael H. Chung, Emma D. Klein, Sara Lewis, Daniel Stocker, B. Marinelli, Adam Bernheim, Guillermo Carbonell, Nicole W. Simons, Bachir Taouli
Despite extraordinary international efforts to dampen the spread and understand the mechanisms behind SARS-CoV-2 infections, accessible predictive biomarkers directly applicable in the clinic are yet to be discovered. Recent studies have revealed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ff426f8187cf11a6ae97d885032676
https://doi.org/10.1101/2021.10.11.21264709
https://doi.org/10.1101/2021.10.11.21264709
Autor:
Laura M. Huckins, Jessica Le Berichel, Brian Fennessy, Edgar Gonzalez-Kozlova, Kai Nie, Seunghee Kim-Schulze, Kevin Tuballes, Lillian Wilkins, Konstantinos Mouskas, Esther Cheng, Aviva G. Beckmann, Mario A. Cedillo, Panagiotis Roussos, Lauren Lepow, Ryan Thompson, Eric E. Schadt, Nancy Francoeur, Nicole W. Simons, Gabriel E. Hoffman, Sacha Gnjatic, Miriam Merad, Noam D. Beckmann, Nicholas Zaki, Thomas U. Marron, Christie Chang, Alexander W. Charney, Vanessa Barcessat, Girish N. Nadkarni, Ying-Chih Wang, Jessica S. Johnson, Diane Marie Del-Valle, Benjamin S. Glicksberg, Robert Sebra
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Summary ParagraphTwo years into the SARS-CoV-2 pandemic, the post-acute sequelae of infection are compounding the global health crisis. Often debilitating, these sequelae are clinically heterogeneous and of unknown molecular etiology. Here, a transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef24eacc298fc90a9761179249ca44c
https://pubmed.ncbi.nlm.nih.gov/34642700
https://pubmed.ncbi.nlm.nih.gov/34642700