Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diane M. Lang"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Dengue virus (DENV) infection is the most prevalent arthropod-borne virus disease and is endemic in more than 100 countries. Several DENV proteins have been shown to target crucial human host proteins to evade innate immune responses and establish a
Externí odkaz:
https://doaj.org/article/3e941e44a5074e25b21bc5f328d39f76
Autor:
Mary J. Savage, James D. Hirsch, Stephen P. Trusko, Yin-Guo Lin, Diane M. Lang, Dorothy G. Flood, Richard W. Scott, David Howland
Publikováno v:
Neurobiology of Aging. 30:1078-1090
Many transgenic mouse models of Alzheimer's disease (AD) that deposit amyloid (Abeta) have been produced, but development of an Abeta-depositing rat model has not been successful. Here, we describe a rat model with extracellular fibrillar Abeta depos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b1d35644ade0577ee0c1539bd2fcf1
https://doi.org/10.1016/j.neurobiolaging.2007.10.006
https://doi.org/10.1016/j.neurobiolaging.2007.10.006
Autor:
Stephen P. Trusko, Meyer Sl, James D. Hirsch, Richard W. Scott, Knight E, Diane M. Lang, Forbes Me
Publikováno v:
Journal of Neurochemistry. 62:825-833
Bioactive brain-derived neurotrophic factor (BDNF) and neurotrophin-3 were produced using the baculovirus expression system and purified to homogeneity using ion-exchange and reversed-phase chromatography. Yields of purified neurotrophin-3 (300-500 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4922fda303c236246c1df29550c9ba
https://doi.org/10.1046/j.1471-4159.1994.62030825.x
https://doi.org/10.1046/j.1471-4159.1994.62030825.x
Autor:
Robert Siman, Richard W. Scott, James D. Hirsch, David Howland, Barry D. Greenberg, Mary J. Savage, Andrew G. Reaume, Dorothy G. Flood, Noboyu Maeda, Diane M. Lang, Stephen P. Trusko
Publikováno v:
Journal of Biological Chemistry. 273:16576-16582
The effects of dietary cholesterol on brain amyloid precursor protein (APP) processing were examined using an APP gene-targeted mouse, genetically humanized in the amyloid beta-peptide (Abeta) domain and expressing the Swedish familial Alzheimer's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0560588341578a0a90569fc480690b9
https://doi.org/10.1074/jbc.273.26.16576
https://doi.org/10.1074/jbc.273.26.16576
Autor:
Andrew G. Reaume, Richard W. Scott, Robert Siman, Barry D. Greenberg, Mary J. Savage, David Howland, Diane M. Lang, Stephen P. Trusko
Publikováno v:
Journal of Biological Chemistry. 271:23380-23388
The processing of the beta-amyloid precursor protein (APP) in vivo has been characterized in a novel animal model that recapitulates, in part, the APP genotype of a familial form of Alzheimer's disease (AD). A gene-targeting strategy was used to intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a84540a1893bcaff41bbb5ddc7d8823
https://doi.org/10.1074/jbc.271.38.23380
https://doi.org/10.1074/jbc.271.38.23380
Autor:
Wim Annaert, Dorothy G. Flood, Yin Guo Lin, Diane M. Lang, Richard W. Scott, Andrew G. Reaume, Bart De Strooper, Stephen P. Trusko, Karen S. Dorfman, Mary J. Savage, Robert Siman
Publikováno v:
Neurobiology of aging. 23(3)
To investigate the consequences of mutant presenilin-1 (PS-1) expression under the control of the normal PS-1 gene, a gene-targeted mouse bearing the FAD mutation P264L was made. Gene-targeted models are distinct from transgenic models because the mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802927b85df5648e4410310bbb057fe5
https://pubmed.ncbi.nlm.nih.gov/11959395
https://pubmed.ncbi.nlm.nih.gov/11959395
Autor:
Ron Bihovsky, Richard W. Scott, John K. Kawooya, Robert Siman, Satish Mallya, Donna Bozyczko-Coyne, Sheryl L. Meyer, Chrysanthe Spais, Diane M. Lang
Publikováno v:
The Biochemical journal. 314
Calpain I is a heterodimeric protein that is part of a family of calcium-activated intracellular cysteine proteases presumed to play a role in mediating signals transduced by calcium. Expression of bioactive recombinant human calpain I has been achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0357ab260c4ddbd97af283b5d341e205
https://pubmed.ncbi.nlm.nih.gov/8670065
https://pubmed.ncbi.nlm.nih.gov/8670065
Autor:
Mary J. Savage, Dorothy G. Flood, Yin-Guo Lin, Karen S. Dorfman, Richard W. Scott, Andrew G. Reuame, Stephen P. Trusko, Diane M. Lang
Publikováno v:
Neurobiology of Aging. 21:133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bdffdf972f18a7890c2bab5885cd2de
https://doi.org/10.1016/s0197-4580(00)82398-2
https://doi.org/10.1016/s0197-4580(00)82398-2
Autor:
Andrew G. Reaume, L. Pinsker, Diane M. Lang, David Howland, Barry D. Greenberg, Stephen P. Trusko, Richard W. Scott, Yin-Guo Lin, Robert Siman, Mary J. Savage, Dorothy G. Flood
Publikováno v:
Neurobiology of Aging. 17:S199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40fc882fd31dbb9db3b50c8b852c7f7a
https://doi.org/10.1016/s0197-4580(96)80802-5
https://doi.org/10.1016/s0197-4580(96)80802-5