Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Diane M McKeone"'
Autor:
Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Dallas R English, Michael D Walsh, Mark Clendenning, Diane M McKeone, Rhiannon J Walters, Aedan Roberts, Sally-Ann Pearson, Erika Pavluk, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, Julie Arnold, Kathy Tucker, Amanda Muir, Michael Field, Sian Greening, Steven Gallinger, Renee Perrier, John A Baron, John D Potter, Robert Haile, Wendy Frankel, Albert de la Chapelle, Finlay Macrae, Christophe Rosty, Neal I Walker, Susan Parry, Joanne P Young
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11636 (2010)
Patients with multiple serrated polyps are at an increased risk for developing colorectal cancer (CRC). Recent reports have linked cigarette smoking with the subset of CRC that develops from serrated polyps. The aim of this work therefore was to inve
Externí odkaz:
https://doaj.org/article/17b278d16068450e836620fc118aeb7e
Autor:
Catherine E. Bond, Cheng Liu, Futoshi Kawamata, Diane M. McKeone, Winnie Fernando, Saara Jamieson, Sally-Ann Pearson, Alexandra Kane, Susan L. Woods, Tamsin R. M. Lannagan, Roshini Somashekar, Young Lee, Troy Dumenil, Gunter Hartel, Kevin J. Spring, Jennifer Borowsky, Lochlan Fennell, Mark Bettington, Jason Lee, Daniel L. Worthley, Barbara A. Leggett, Vicki L. J. Whitehall
Publikováno v:
Epigenetics, Vol 13, Iss 1, Pp 40-48 (2018)
Colorectal cancer is a major cause of cancer death and approximately 20% arises within serrated polyps, which are under-recognized and poorly understood. Human serrated colorectal polyps frequently exhibit both oncogenic BRAF mutation and widespread
Externí odkaz:
https://doaj.org/article/a0eb35f1f5c1498b9b8dd60644c1c526
Autor:
Joanne P. Young, Michael A. McGuckin, Noralane M. Lindor, Stephen N. Thibodeau, Bharati Bapat, Loic Le Marchand, John D. Potter, John A. Baron, Robert W. Haile, Finlay A. Macrae, Susan Parry, Sonja Woodall, Michael R. Gattas, Elise Pelzer, Kathy Tucker, Amanda Muir, Jack Goldblatt, Jill George, Graeme K. Suthers, Kerry D. Phillips, Mark A. Jenkins, John L. Hopper, Amanda B. Spurdle, Diane M. McKeone, Rhiannon Walters, Mark Clendenning, Sven T. Arnold, Sally-Ann Pearson, Margaret C. Cummings, Daniel D. Buchanan, Michael D. Walsh
Supplementary Data from Lynch Syndrome–Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf60a94d58ca430f1ec2a41acc1a07aa
https://doi.org/10.1158/1078-0432.22442241.v1
https://doi.org/10.1158/1078-0432.22442241.v1
Autor:
Joanne P. Young, Michael A. McGuckin, Noralane M. Lindor, Stephen N. Thibodeau, Bharati Bapat, Loic Le Marchand, John D. Potter, John A. Baron, Robert W. Haile, Finlay A. Macrae, Susan Parry, Sonja Woodall, Michael R. Gattas, Elise Pelzer, Kathy Tucker, Amanda Muir, Jack Goldblatt, Jill George, Graeme K. Suthers, Kerry D. Phillips, Mark A. Jenkins, John L. Hopper, Amanda B. Spurdle, Diane M. McKeone, Rhiannon Walters, Mark Clendenning, Sven T. Arnold, Sally-Ann Pearson, Margaret C. Cummings, Daniel D. Buchanan, Michael D. Walsh
Purpose: The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers arising in Lynch syndrome families.Experimental Design: This observational study in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bf8927b319a3e1c6bfb1f76b69a428
https://doi.org/10.1158/1078-0432.c.6519033
https://doi.org/10.1158/1078-0432.c.6519033
Autor:
Lochlan J Fennell, Gunter Hartel, Diane M McKeone, Catherine E Bond, Alexandra Kane, Barbara A Leggett, Ann-Marie Patch, Vicki LJ Whitehall
BackgroundResearching the murine epigenome in disease models has been hampered by the lack of an appropriate and cost-effective DNA methylation array. Until recently, investigators have been limited to the relatively expensive and analysis intensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::785888697d50cbdccb97e80abd13d0e7
https://doi.org/10.1101/2022.03.07.483250
https://doi.org/10.1101/2022.03.07.483250
Autor:
Chang Su, Lochlan J Fennell, Catherine E Bond, Alexandra M Kane, Genevieve Kerr, Thierry Jardé, Diana Micati, Rebekah M Engel, Wing Hei Chan, Sara Hlavca, Stuart Archer, Paul J McMurrick, Heinz Hammerlindl, Fayth Lim, Basit Salik, Diane M McKeone, Gunter Hartel, Jennifer Borowsky, Rahul Ladwa, Barbara A Leggett, Helmut Schaider, Helen E Abud, Glen M Boyle, Matthew E Burge, Vicki LJ Whitehall
PurposeRegorafenib is a multi-kinase inhibitor approved for refractory metastatic colorectal cancer. Previous studies have suggested that combining kinase inhibitors with aspirin may improve patient outcomes. We aimed to determine the effects of aspi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08e038486c64e20f79f3d5071b95732
https://doi.org/10.1101/2022.02.11.480021
https://doi.org/10.1101/2022.02.11.480021
Autor:
Lochlan J. Fennell, Gunter Hartel, Diane M. McKeone, Catherine E. Bond, Alexandra Kane, Barbara A. Leggett, Ann-Marie Patch, Vicki L.J. Whitehall
Publikováno v:
Cell Reports Methods. 2:100323
Researching the murine epigenome in disease models has been hampered by the lack of appropriate and cost-effective DNA methylation arrays. Here we perform a comprehensive, comparative analysis between the Mouse Methylation BeadChip (MMB) and reduced-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6845d804a44673b38c294fb13988305d
https://doi.org/10.1016/j.crmeth.2022.100323
https://doi.org/10.1016/j.crmeth.2022.100323
Autor:
Alexandra M, Kane, Cheng, Liu, Dewan T, Akhter, Diane M, McKeone, Craig A, Bell, Kristofer J, Thurecht, Barbara A, Leggett, Vicki L J, Whitehall
Publikováno v:
Digestive diseases and sciences. 66(12)
Colorectal cancer is a leading cause of cancer-related death worldwide and approximately 20% of cases can be attributed to a mutation in the BRAF oncogene. Curcumin is a promising chemopreventive agent with various anti-cancer benefits. Although curc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc28f7cbaf8a8778ff75595afd3735a4
https://pubmed.ncbi.nlm.nih.gov/33387125
https://pubmed.ncbi.nlm.nih.gov/33387125
Autor:
Troy D, Dumenil, Leesa F, Wockner, Mark, Bettington, Diane M, McKeone, Kerenaftali, Klein, Lisa M, Bowdler, Grant W, Montgomery, Barbara A, Leggett, Vicki L J, Whitehall
Publikováno v:
Genes, chromosomescancer. 53(7)
Formalin fixation and embedding of clinical tissue samples in paraffin is a common method for archiving biological material. These samples are often well annotated and provide an invaluable resource for research. However, this process of fixation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5cebcbe96eaa5a65c9cedf903cb259e
https://pubmed.ncbi.nlm.nih.gov/24677610
https://pubmed.ncbi.nlm.nih.gov/24677610
Autor:
Alexandra M. Kane, Lochlan J. Fennell, Cheng Liu, Jennifer Borowsky, Diane M. McKeone, Catherine E. Bond, Stephen Kazakoff, Ann-Marie Patch, Lambros T. Koufariotis, John Pearson, Nicola Waddell, Barbara A. Leggett, Vicki L.J. Whitehall
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 120-128 (2020)
The serrated neoplasia pathway gives rise to a distinct subgroup of colorectal cancers distinguished by the presence of mutant BRAFV600E and the CpG Island Methylator Phenotype (CIMP). BRAF mutant CRC are commonly associated with microsatellite insta
Externí odkaz:
https://doaj.org/article/54cf7836ff7a4539bd24d079728bf56e