Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Diane Ly"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 24, Iss , Pp 100-106 (2022)
Introduction: Clobazam is a benzodiazepine drug, used to treat Lennox-Gastaut syndrome in patients aged 2 years and older. Objective: To support patient care, our laboratory developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) method
Externí odkaz:
https://doaj.org/article/cf818b34d7e34d798f6d5c3b3b659649
Autor:
Jeremy S. Lum, Mikayla L. Brown, Natalie E. Farrawell, Luke McAlary, Diane Ly, Christen G. Chisholm, Josh Snow, Kara L. Vine, Tim Karl, Fabian Kreilaus, Lachlan E. McInnes, Sara Nikseresht, Paul S. Donnelly, Peter J. Crouch, Justin J. Yerbury
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The synthetic copper-containing compound, CuATSM, has emerged as one of the most promising drug candidates developed for the treatment of amyotrophic lateral sclerosis (ALS). Multiple studies have reported CuATSM treatment provides therapeut
Externí odkaz:
https://doaj.org/article/c146cd7fdab24b4d90091d3aa58e739c
Autor:
Stephan Brouwer, Timothy C. Barnett, Diane Ly, Katherine J. Kasper, David M. P. De Oliveira, Tania Rivera-Hernandez, Amanda J. Cork, Liam McIntyre, Magnus G. Jespersen, Johanna Richter, Benjamin L. Schulz, Gordon Dougan, Victor Nizet, Kwok-Yung Yuen, Yuanhai You, John K. McCormick, Martina L. Sanderson-Smith, Mark R. Davies, Mark J. Walker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The pathogenesis of Streptococcus pyogenes (GAS) causing scarlet fever has been associated with the presence of prophages, such as ΦHKU.vir, and their products. Here, the authors characterize the exotoxins SpeC and Spd1 of ΦHKU.vir and show these t
Externí odkaz:
https://doaj.org/article/6e79b1f03e764489835c1a7815d1f404
Autor:
Jonathan G. Williams, Diane Ly, Nicholas J. Geraghty, Jason D. McArthur, Heema K. N. Vyas, Jody Gorman, James A. Tsatsaronis, Ronald Sluyter, Martina L. Sanderson-Smith
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Invasive infections due to group A Streptococcus (GAS) advance rapidly causing tissue degradation and unregulated inflammation. Neutrophils are the primary immune cells that respond to GAS. The neutrophil response to GAS was characterised in response
Externí odkaz:
https://doaj.org/article/e5846be346c848a7b48a5bbc78c40423
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 5, Pp 749-750 (2017)
Externí odkaz:
https://doaj.org/article/f2dd4e6ad8ea4a16ab721e8461e4d186
Autor:
Martina L Sanderson-Smith, Yueling Zhang, Diane Ly, Deborah Donahue, Andrew Hollands, Victor Nizet, Marie Ranson, Victoria A Ploplis, Mark J Walker, Francis J Castellino
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003469 (2013)
Recruitment of the serine protease plasmin is central to the pathogenesis of many bacterial species, including Group A streptococcus (GAS), a leading cause of morbidity and mortality globally. A key process in invasive GAS disease is the ability to a
Externí odkaz:
https://doaj.org/article/fca5dc76a6ce464cbcffb989cb933e88
Publikováno v:
Purinergic Signalling. 18:451-467
Mutant superoxide dismutase 1 (SOD1) can be constitutively released from motor neurons and transmitted to naïve motor neurons to promote the progression of amyotrophic lateral sclerosis (ALS). However, the biological impacts of this process and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22a4d70f99171c893e381b7f5acb3ac
https://doi.org/10.1007/s11302-022-09863-5
https://doi.org/10.1007/s11302-022-09863-5
Autor:
Justin J. Yerbury, Nicholas J. Geraghty, Thomas V. Guy, Lucia Sin, Diane Ly, Debbie Watson, Peter Cuthbertson, Ronald Sluyter, Anjila Dongol, Bradley J. Turner, Reece A. Sophocleous
Publikováno v:
Purinergic Signalling. 16:109-122
The ATP-gated P2X7 ion channel has emerging roles in amyotrophic lateral sclerosis (ALS) progression. Pharmacological blockade of P2X7 with Brilliant Blue G can ameliorate disease in SOD1G93A mice, but recent data suggests that this antagonist displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4b4c55ee6bf0086f995795159d301f9
https://doi.org/10.1007/s11302-020-09692-4
https://doi.org/10.1007/s11302-020-09692-4
Autor:
Nicholas J. Geraghty, Amirazin Hadjiashrafi, Debbie Watson, Peter Cuthbertson, Sam R. Adhikary, Diane Ly, Thomas V. Guy, Stephen J. Fuller, Ronald Sluyter
Publikováno v:
Clinical Science. 134:207-223
Background: Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for blood cancers; but results in the development of graft-versus-host disease (GVHD) in up to 70% of recipients. During GVHD, tissue damage results in ATP r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bd0eb181bef001011aec7324462a5c
https://doi.org/10.1042/cs20191086
https://doi.org/10.1042/cs20191086
Autor:
Lachlan E. McInnes, Sara Nikseresht, Kara L. Vine, Fabian Kreilaus, Paul S. Donnelly, Josh Snow, Tim Karl, Luke McAlary, Natalie E. Farrawell, Mikayla L. Brown, Jeremy S. Lum, Diane Ly, Justin J. Yerbury, Peter J. Crouch, Christen G. Chisholm
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The synthetic copper-containing compound, CuATSM, has emerged as one of the most promising drug candidates developed for the treatment of amyotrophic lateral sclerosis (ALS). Multiple studies have reported CuATSM treatment provides therapeutic effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f43f985c2a6fbc6cc4ccd1e17d749a
http://europepmc.org/articles/PMC8481268
http://europepmc.org/articles/PMC8481268