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Akademický článek

Cervical intervertebral disc disease in 60 Yorkshire terriers

Autor: Viktor Palus, Ladislav Stehlik, Alois Necas, Robert Srnec, Lucie Urbanova, Diane Lu

Publikováno v: Frontiers in Veterinary Science, Vol 10 (2023)

Intervertebral disc extrusion (IVDE) is a common neurological condition in many dog breeds. This study aimed to describe this condition in Yorkshire terriers (YT) and calculate the prevalence of this condition amongst the YTs with neurological diseas

Externí odkaz: https://doaj.org/article/c24b701761f34d3b8ea09057f51832bc

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Health differences by entry stream among Canadian Armed Forces officer cadets

Autor: Serena Chin, Samantha Carlucci, Heather J. McCuaig Edge, Diane Lu

Publikováno v: Journal of Military, Veteran and Family Health. 8:45-57

LAY SUMMARYThis study compared the baseline physical and mental health of officer candidates attending military college and officer training programs (i.e., non-direct-entry officer or non-DEO stream) with those of officers entering through a direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0df05cf3930b8933d01851b7057a0fce
https://doi.org/10.3138/jmvfh-2021-0124

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Myocarditis or Pericarditis Events After BNT162b2 Vaccination in Individuals Aged 12 to 17 Years in Ontario, Canada

Autor: Sarah A. Buchan, Sarah Alley, Chi Yon Seo, Caitlin Johnson, Jeffrey C. Kwong, Sharifa Nasreen, Nisha Thampi, Diane Lu, Tara M. Harris, Andrew Calzavara, Sarah E. Wilson

Publikováno v: JAMA Pediatrics. 177:410

ImportanceThe risk of myocarditis or pericarditis after COVID-19 messenger RNA vaccines varies by age and sex, and there is some evidence to suggest increasing risk with shorter intervals between dose 1 and 2 (ie, interdose interval).ObjectiveTo esti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9617be6f6fd666fd19e8130c9f7921b3
https://doi.org/10.1001/jamapediatrics.2022.6166

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Three sequential outbreaks of Group A Streptococcus over a two-year period at the Canadian Forces Leadership and Recruit School, St. Jean Garrison, Québec

Autor: Kirsten Barnes, Irene Martin, Barbara Strauss, Martine Massé, Diane Lu, François Gagnon, Eric Girard, Martin Tepper, Walter Demczuk

Publikováno v: Can Commun Dis Rep

Background Since December 2016, the basic military training (BMT) facility for the Canadian Armed Forces (CAF) has experienced repeated outbreaks of Group A Streptococcus (GAS). In 2018, a voluntary mass antibiotic prophylaxis (MAP) program was imple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de600992aa43e37d8ccf8ff7678007c2
https://doi.org/10.14745/ccdr.v46i09a02

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Epidemiology of myocarditis and pericarditis following mRNA vaccines in Ontario, Canada: by vaccine product, schedule and interval

Autor: Sarah A. Buchan, Chi Yon Seo, Caitlin Johnson, Sarah Alley, Jeffrey C. Kwong, Sharifa Nasreen, Andrew Calzavara, Diane Lu, Tara M. Harris, Kelly Yu, Sarah E. Wilson

ImportanceIncreased rates of myocarditis/pericarditis following COVID-19 mRNA vaccines have been observed. However, little data are available related to product-specific differences, which have important programmatic impacts.ObjectiveThe objective of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99eb23e9c06289b0d705bf486a94aef3
https://doi.org/10.1101/2021.12.02.21267156

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Akademický článek

Splice modulators target PMS1 to reduce somatic expansion of the Huntington’s disease-associated CAG repeat

Autor: Zachariah L. McLean, Dadi Gao, Kevin Correia, Jennie C. L. Roy, Shota Shibata, Iris N. Farnum, Zoe Valdepenas-Mellor, Marina Kovalenko, Manasa Rapuru, Elisabetta Morini, Jayla Ruliera, Tammy Gillis, Diane Lucente, Benjamin P. Kleinstiver, Jong-Min Lee, Marcy E. MacDonald, Vanessa C. Wheeler, Ricardo Mouro Pinto, James F. Gusella

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Huntington’s disease (HD) is a dominant neurological disorder caused by an expanded HTT exon 1 CAG repeat that lengthens huntingtin’s polyglutamine tract. Lowering mutant huntingtin has been proposed for treating HD, but genetic modifier

Externí odkaz: https://doaj.org/article/04c90e61e38c4922b3fb3425418eb127

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Epidemiology of Myocarditis and Pericarditis Following mRNA Vaccination by Vaccine Product, Schedule, and Interdose Interval Among Adolescents and Adults in Ontario, Canada

Autor: Sarah A, Buchan, Chi Yon, Seo, Caitlin, Johnson, Sarah, Alley, Jeffrey C, Kwong, Sharifa, Nasreen, Andrew, Calzavara, Diane, Lu, Tara M, Harris, Kelly, Yu, Sarah E, Wilson

Publikováno v: JAMA Network Open. 5:e2218505

Increased rates of myocarditis or pericarditis following receipt of COVID-19 mRNA vaccines have been observed. However, few available data are associated with differences in rates of myocarditis or pericarditis specific to vaccine products, which may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426055697a10c97079b43af1d9c89e37
https://doi.org/10.1001/jamanetworkopen.2022.18505

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