Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diane L. Redmond"'
Autor:
Raja Yaga, J. B. Matthews, Mintu Nath, John T. Jones, David P. Knox, Diane L. Redmond, Craig A Watkins, Alasdair J. Nisbet
Publikováno v:
International Journal for Parasitology. 38:829-838
Suppression subtractive hybridisation was used to enrich genes expressed in a stage-specific manner in infective, exsheathed L3s (xL3) versus early L4s of the ovine nematode, Teladorsagia circumcincta prior to gene expression profiling by microarray.
Autor:
A. M. Halliday, W. D. Smith, Frank Jackson, J. B. Matthews, David P. Knox, S. K. Smith, Diane L. Redmond
Publikováno v:
International Journal for Parasitology. 36:277-286
Teladorsagia circumcincta is a common, pathogenic abomasal nematode of sheep. In order to improve disease control in parasite isolates resistant to several anthelmintics, alternative methods must be sought. Sheep develop acquired immunity to T. circu
Publikováno v:
International Journal for Parasitology. 34:1347-1353
High levels of protection can be attained against Haemonchus contortus challenge infection in sheep using native antigens isolated from the gut of the adult parasite. However, vaccination with recombinant forms of these antigens, or components thereo
Autor:
David P. Knox, Diane L. Redmond, Philip Skuce, Dan Pettit, W. David Smith, George F.J. Newlands
Publikováno v:
International Journal for Parasitology. 33:1129-1137
Substantial progress has been made in the last decade in identifying several antigens from Haemonchus contortus which, in their native form, stimulate useful levels of protective immunity (70-95% reductions in faecal egg output) in the ovine host. Mu
Publikováno v:
Veterinary Parasitology. 101:311-335
Rapid developments in molecular biology have had an enormous impact on the prospects for the development of vaccines to control the major nematode and trematode infestations of livestock. Vaccine candidates are purified using conventional protein che
Autor:
Diane L. Redmond, David P. Knox
Publikováno v:
Molecular and Biochemical Parasitology. 117:107-110
Publikováno v:
Molecular and Biochemical Parasitology. 85:77-87
Antisera from lambs immunised with the Haemonchus contortus integral membrane protein complex, Haemonchus galactose-containing glycoprotein (H-gal-GP), the lambs being refractory to subsequent challenge, were used to identify several clones from an a
Autor:
S. K. Smith, Philip Skuce, W. D. Smith, George F.J. Newlands, D. Pettit, Alasdair J. Nisbet, Diane L. Redmond
Publikováno v:
Parasitology. 133(Pt 3)
Substantial protection against the economically important parasitic nematode Haemonchus contortus has been achieved by immunizing sheep with a glycoprotein fraction isolated from the intestinal membranes of the worm (H-gal-GP). Previous studies showe
Publikováno v:
Parasite immunology. 27(4)
SUMMARY Previous work has shown that a protein extract enriched for cysteine protease activity (TSBP) prepared from adult Haemonchus contortus using thiol sepharose affinity chromatography confers substantial protection against a single challenge inf
Autor:
David P. Knox, Diane L. Redmond
Publikováno v:
Vaccine. 22(31-32)
Vaccination with a membrane-bound thiol Sepharose-binding fraction (TSBP) of adult Haemonchus contortus has been shown to confer significant levels of protection against homologous challenge in sheep. This fraction is greatly enriched for cysteine pr