Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Diane L. Kamen"'
Autor:
Melissa E. Munroe, Kendra A. Young, Joel M. Guthridge, Diane L. Kamen, Gary S. Gilkeson, Michael H. Weisman, Mariko L. Ishimori, Daniel J. Wallace, David R. Karp, John B. Harley, Jill M. Norris, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is propelled by pathogenic autoantibody (AutoAb) and immune pathway dysregulation. Identifying populations at risk of reaching classified SLE is essential to curtail inflammatory damage. Lupus blood relatives (Rel)
Externí odkaz:
https://doaj.org/article/7621afd0bdc04818b856c37f083c1113
Autor:
Nancy J. Olsen, Judith A. James, Cristina Arriens, Mariko L. Ishimori, Daniel J. Wallace, Diane L. Kamen, Benjamin F. Chong, Duanping Liao, Vernon M. Chinchilli, David R. Karp
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Onset of systemic lupus erythematosus (SLE) is preceded by a preclinical phase characterized by expression of autoantibodies and nonspecific clinical symptoms. Hydroxychloroquine is a treatment for lupus that is widely used based
Externí odkaz:
https://doaj.org/article/b0b1169a7a71454b8f329119cff33b8b
Autor:
Zhenwu Luo, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Min Li, Quan-Zhen Li, Lei Huang, Betty P. Tsao, Diane L. Kamen, Jim C. Oates, Zihai Li, Gary S. Gilkeson, Wei Jiang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Blood microbiome is important to investigate microbial-host interactions and the effects on systemic immune perturbations. However, this effort has met with major challenges due to low microbial biomass and background artifacts. In the current study,
Externí odkaz:
https://doaj.org/article/89d071aa6a354071b293ab845a612355
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9
Autor:
Bethany J. Wolf, Paula S. Ramos, J. Madison Hyer, Viswanathan Ramakrishnan, Gary S. Gilkeson, Gary Hardiman, Paul J. Nietert, Diane L. Kamen
Publikováno v:
Genes, Vol 9, Iss 10, p 496 (2018)
Development and progression of many human diseases, such as systemic lupus erythematosus (SLE), are hypothesized to result from interactions between genetic and environmental factors. Current approaches to identify and evaluate interactions are limit
Externí odkaz:
https://doaj.org/article/343cc69cfd3d434e8f84bf4e49283069
Autor:
Ida J. Spruill, Renata Serricchio Leite, Jyotika K. Fernandes, Diane L. Kamen, Marvella E. Ford, Carolyn Jenkins, Kelly J. Hunt, Jeannette O. Andrews
Publikováno v:
Gateways, Vol 6, Iss 1 (2013)
Engaging communities is highly recommended in the conduct of health research among vulnerable populations. The strength of community-engaged research is well documented and is recognised as a useful approach for eliminating health disparities and imp
Externí odkaz:
https://doaj.org/article/3d18d40060f44db09adbe88a0066ecda
Autor:
Rufei Lu, Julie M. Robertson, Benjamin F. Bruner, Joel M. Guthridge, Barbara R. Neas, Swapan K. Nath, Jennifer A. Kelly, Kathy L. Moser Sivils, Eliza F. Chakravarty, Diane L. Kamen, Gary S. Gilkeson, Daniel J. Wallace, Michael H. Weisman, R. Hal Scofield, John B. Harley, Judith A. James
Publikováno v:
Autoimmune Diseases, Vol 2012 (2012)
Purpose. This study evaluates high-throughput autoantibody screening and determines associated systemic lupus erythematosus (SLE) clinical features in a large lupus cohort. Methods. Clinical and demographic information, along with serum samples, were
Externí odkaz:
https://doaj.org/article/04308cbc01d54b4880b3f8fd75e99adc
Autor:
Diane L Kamen, Julie A Birt, Monica A Hadi, Elizabeth Gibbons, Donald M Bushnell, Ren Yu, Laure A Delbecque, Kirstin Griffing, Anca Askanase
Publikováno v:
Lupus. 32:342-351
Background Many people with systemic lupus erythematosus (SLE) experience joint pain, swelling, and stiffness. These joint symptoms are associated with problems in physical functioning and work disability. We used survey data from adults with SLE to
Autor:
Sindhu R. Johnson, Dafna D. Gladman, Hermine I. Brunner, David Isenberg, Ann E. Clarke, Megan R. W. Barber, Laurent Arnaud, Paul R. Fortin, Marta Mosca, Alexandre E. Voskuyl, Susan Manzi, Cynthia Aranow, Anca Askanase, Graciela S. Alarcón, Sang‐Cheol Bae, Nathalie Costedoat‐Chalumeau, Jessica A. English, Guillermo J. Pons‐Estel, Bernardo A. Pons‐Estel, Rebecca Gilman, Ellen M. Ginzler, John G. Hanly, Soren Jacobsen, Kenneth Kalunian, Diane L. Kamen, Chynace Lambalgen, Alexandra Legge, S. Sam Lim, Anselm Mak, Eric F. Morand, Christine A. Peschken, Michelle Petri, Anisur Rahman, Rosalind Ramsey‐Goldman, John A. Reynolds, Juanita Romero‐Diaz, Guillermo Ruiz‐Irastorza, Jorge Sanchez‐Guerrero, Elisabet Svenungsson, Zahi Touma, Murray Urowitz, Evelyne Vinet, Ronald F. van Vollenhoven, Heather Waldhauser, Daniel J. Wallace, Asad Zoma, Ian N. Bruce
Publikováno v:
Johnson, S R, Gladman, D D, Brunner, H I, Isenberg, D, Clarke, A E, Barber, M R W, Arnaud, L, Fortin, P R, Mosca, M, Voskuyl, A E, Manzi, S, Aranow, C, Askanase, A, Alarcón, G S, Bae, S-C, Costedoat-Chalumeau, N, English, J, Pons-Estel, G J, Pons-Estel, B A, Gilman, R, Ginzler, E, Hanly, J G, Jacobsen, S, Kalunian, K, Kamen, D L, Lambalgen, C, Legge, A, Lim, S S, Mak, A, Morand, E F, Peschken, C, Petri, M, Rahman, A, Ramsey-Goldman, R, Reynolds, J A, Romero-Diaz, J, Ruiz-Irastorza, G, Sanchez-Guerrero, J, Svenungsson, E, Touma, Z, Urowitz, M, Vinet, E, van Vollenhoven, R F, Waldhauser, H, Wallace, D J, Zoma, A & Bruce, I N 2023, ' Evaluating the construct of damage in systemic lupus erythematosus ', Arthritis Care & Research, vol. 75, no. 5, pp. 998-1006 . https://doi.org/10.1002/acr.24849
Arthritis Care and Research. John Wiley and Sons Inc.
Johnson, S R, Gladman, D D, Brunner, H I, Isenberg, D, Clarke, A E, Barber, M R W, Arnaud, L, Fortin, P R, Mosca, M, Voskuyl, A, Manzi, S, Aranow, C, Askanase, A, Alarcón, G S, Bae, S-C, Costedoat-Chalumeau, N, English, J, Pons-Estel, G J, Pons-Estel, B A, Gilman, R, Ginzler, E, Hanly, J G, Jacobsen, S, Kalunian, K, Kamen, D L, Lambalgen, C, Legge, A, Lim, S S, Mak, A, Morand, E F, Peschken, C, Petri, M, Rahman, A, Ramsey-Goldman, R, Reynolds, J A, Romero-Diaz, J, Ruiz-Irastorza, G, Sanchez-Guerrero, J, Svenungsson, E, Touma, Z, Urowitz, M, Vinet, E, van Vollenhoven, R F, Waldhauser, H, Wallace, D, Zoma, A & Bruce, I N 2022, ' Evaluating the construct of damage in systemic lupus erythematosus ', Arthritis Care and Research . https://doi.org/10.1002/acr.24849
Arthritis Care and Research. John Wiley and Sons Inc.
Johnson, S R, Gladman, D D, Brunner, H I, Isenberg, D, Clarke, A E, Barber, M R W, Arnaud, L, Fortin, P R, Mosca, M, Voskuyl, A, Manzi, S, Aranow, C, Askanase, A, Alarcón, G S, Bae, S-C, Costedoat-Chalumeau, N, English, J, Pons-Estel, G J, Pons-Estel, B A, Gilman, R, Ginzler, E, Hanly, J G, Jacobsen, S, Kalunian, K, Kamen, D L, Lambalgen, C, Legge, A, Lim, S S, Mak, A, Morand, E F, Peschken, C, Petri, M, Rahman, A, Ramsey-Goldman, R, Reynolds, J A, Romero-Diaz, J, Ruiz-Irastorza, G, Sanchez-Guerrero, J, Svenungsson, E, Touma, Z, Urowitz, M, Vinet, E, van Vollenhoven, R F, Waldhauser, H, Wallace, D, Zoma, A & Bruce, I N 2022, ' Evaluating the construct of damage in systemic lupus erythematosus ', Arthritis Care and Research . https://doi.org/10.1002/acr.24849
The Systemic Lupus International Collaborating Clinics (SLICC), American College of Rheumatology (ACR), and the Lupus Foundation of America are developing a revised systemic lupus erythematosus (SLE) damage index (the SLICC/ACR Damage Index [SDI]). S
Autor:
Lingxiao Xu, Jian Zhao, Qing Sun, Xue Xu, Lei Wang, Ting Liu, Yunjuan Wu, Jingfeng Zhu, Linyu Geng, Yun Deng, Alexander Awgulewitsch, Diane L Kamen, Jim C Oates, Prithvi Raj, Edward K Wakeland, R Hal Scofield, Joel M Guthridge, Judith A James, Bevra H Hahn, Deborah K McCurdy, Fang Wang, Miaojia Zhang, Wenfeng Tan, Gary S Gilkeson, Betty P Tsao
Publikováno v:
Annals of the Rheumatic Diseases. 81:1712-1721
ObjectivesFamilies that contain multiple siblings affected with childhood onset of systemic lupus erythematosus (SLE) likely have strong genetic predispositions. We performed whole exome sequencing (WES) to identify familial rare risk variants and to