Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Diane L. Hatchell"'
Publikováno v:
Ophthalmic Research. 35:48-53
The purpose of this study was to determine whether the subretinal space would provide immune privilege for pancreatic islet transplantation. Islets from outbred Sprague Dawley (SD) rats were isolated by collagenase digestion, and about 200 handpicked
Autor:
Daijiro Miki, Kimberly A. Smeds, Anne Pfister-Serres, Terry Kim, Kourosh Dastgheib, Mark W. Grinstaff, Diane L. Hatchell, Makoto Inoue
Publikováno v:
Cornea. 21:393-399
To determine whether a novel photocrosslinkable polymer synthesized from hyaluronic acid would seal experimental full-thickness corneal lacerations in a rabbit model.A solution of hyaluronic acid was modified with methacrylate groups (HA-MA), precipi
Autor:
Kourosh Dastgheib, Makoto Inoue, Mark W. Grinstaff, Kimberly A. Smeds, Anne Pfister-Serres, Daijiro Miki, Diane L. Hatchell
Publikováno v:
Journal of Biomedical Materials Research. 54:115-121
In situ photopolymerization is an exciting new technique for tissue engineering. Two photocrosslinkable polysaccharides composed of alginate and hyaluronan are described that upon photolysis form soft, flexible, and viscoelastic hydrogels. The degree
Publikováno v:
Journal of Macromolecular Science, Part A. 36:981-989
A modified hyaluronic acid (HA) biopolymer was synthesized that can be photocrosslinked to form a stable hydrogel. The chemical and physical properties including the amount of modification of the polymer with methacrylate anhydride, the viscosity of
Publikováno v:
The American Journal of the Medical Sciences. 313:131-137
Adhesion molecule expression on peripheral blood leukocytes from diabetic patients with severe retinopathy and age-matched control subjects was assessed. Expression of CD11b, CD18, and L-selectin was measured on granulocytes and lymphocytes in whole
Publikováno v:
Microcirculation. 3:271-278
Polymorphonuclear leukocytes (PMN) have been found to be less deformable in humans with non-insulin-dependent diabetes. It has therefore been hypothesized that white blood cells (WBC) may affect the development of diabetic microangiopathy. This study
Publikováno v:
Experimental Eye Research. 58:641-647
Recent studies suggest that leukocytes may contribute to capillary occlusion and endothelial cell injury in diabetic retinopathy. The present study is an attempt to determine whether high glucose concentration/hyperosmolar conditions would increase n
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 232:347-354
Bleb fibrosis after glaucoma filtering surgery and proliferative vitreoretinopathy after retinal detachment surgery are complications caused by proliferation of fibroblasts or fibroblastlike cells. The anthracycline daunomycin (DNM) has been used for
Autor:
E.J. Cragoe, A.G. Harris, J. Dörffler-Melly, Karl-E. Arfors, S.E. Eriksson, Antonio Colantuoni, S. Wen, T.C. Skalak, I. Herrig, A. Bollinger, M. Intaglietta, B. Fagrell, Diane L. Hatchell, Michelle C. Mazzoni, M. Schiesser, U.K. Franzeck, Silvia Bertuglia, L. Rosén
Publikováno v:
International Journal of Microcirculation. 14:185-194
Publikováno v:
International Journal of Microcirculation. 14:159-166
Although diabetic retinopathy is a leading cause of blindness, the mechanisms underlying the disorder remain unresolved. Recent studies have reported both an increase in viscosity and a decrease in filterability of blood in diabetes, as well as incre