Výsledky vyhledávání - "Diane L. Cope"

Altered Structure and Anion Transport Properties of Band 3 (AE1, SLC4A1) in Human Red Cells Lacking Glycophorin A

Autor: Makoto Uchikawa, Diane L. Cope, Rui-jun Pan, Robert B. Gunn, Lesley J. Bruce, Michael J. A. Tanner, Richard J. Cherry

Publikováno v: Journal of Biological Chemistry. 279:2414-2420

We have studied the properties of band 3 in different glycophorin A (GPA)-deficient red cells. These red cells lack either both GPA and glycophorin B (GPB) (M(k)M(k) cells) or GPA (En(a-) cells) or contain a hybrid of GPA and GPB (MiV cells). Sulfate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c516e9aa344037604ac300bae718e023
https://doi.org/10.1074/jbc.m309826200

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Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

Autor: Kathy H. Surinya, K. Siddle, Diane L. Cope, L. Molina, Maria A. Soos, C. A. Niesler, Birgitte Ursø

Publikováno v: Biochemical Society Transactions. 29:513-525

The physiological roles of insulin and insulin-like growth factors (IGFs) are distinct, with insulin acting to regulate cellular uptake and metabolism of fuels, whereas IGFs promote cell growth, survival and differentiation. The only components of si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfa409775af659fbfc92b0a2ef6f5ea
https://doi.org/10.1042/bst0290513

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Identification of further important residues within the Glut4 carboxy-terminal tail which regulate subcellular trafficking

Autor: Shu-Hua Lee, Gwyn W. Gould, Derek R. Melvin, Diane L Cope

Publikováno v: FEBS Letters. 481:261-265

The insulin-responsive glucose transporter, Glut4, exhibits a unique subcellular distribution such that in the absence of insulin >95% of the protein is stored within intracellular membranes. In response to insulin, Glut4 exhibits a large mobilisatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1904db9ca9ba6799e6eaa4b6fab784e3
https://doi.org/10.1016/s0014-5793(00)02021-4

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Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes

Autor: Stephen O'Rahilly, Jon P. Whitehead, Diane L. Cope, Amanda C. Hayward, Birgitte Ursø, Kenneth Siddle, H. E. Kalloo-Hosein

Publikováno v: The Journal of biological chemistry. 274(43)

Insulin and insulin-like growth factors (IGFs) elicit distinct but overlapping biological effects in vivo. To investigate whether differences in intrinsic signaling capacity of receptors contribute to biological specificity, we constructed chimeric r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1367c03190e325ebb466394ef8ce6693
https://pubmed.ncbi.nlm.nih.gov/10521479

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Specificity in ligand binding and intracellular signalling by insulin and IGF receptors

Autor: C. A. Niesler, Katharina Helen Surinya, Birgitte Ursø, Maria A. Soos, L. Molina, Diane L. Cope, K. Siddle

Publikováno v: Biochemical Society Transactions. 29:A57-A57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::840c0c27bcc708c4688385e55df64740
https://doi.org/10.1042/bst029a057b

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