Výsledky vyhledávání - "Diane L. Church"

Akademický článek

CATP-6, a C. elegans ortholog of ATP13A2 PARK9, positively regulates GEM-1, an SLC16A transporter.

Autor: Eric J Lambie, Pamela J Tieu, Nadja Lebedeva, Diane L Church, Barbara Conradt

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77202 (2013)

In previous work, we found that gain-of-function mutations that hyperactivate GEM-1 (an SLC16A transporter protein) can bypass the requirement for GON-2 (a TRPM channel protein) during the initiation of gonadogenesis in C. elegans. Consequently, we p

Externí odkaz: https://doaj.org/article/b9a7bb67620847c799bdf88ed7f26b85

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The Promotion of Gonadal Cell Divisions by the Caenorhabditis elegans TRPM Cation Channel GON-2 Is Antagonized by GEM-4 Copine

Autor: Diane L. Church, Eric J. Lambie

Publikováno v: Genetics. 165:563-574

The initiation of postembryonic cell divisions by the gonadal precursors of C. elegans requires the activity of gon-2. gon-2 encodes a predicted cation channel (GON-2) of the TRPM subfamily of TRP proteins and is likely to mediate the influx of Ca2+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33782c9f318f0b9603083c215c610d95
https://doi.org/10.1093/genetics/165.2.563

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The C. elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression

Autor: Rachel J. West, Eric J. Lambie, Andrew Y. Sun, Diane L. Church

Publikováno v: Gene. 266:103-110

The C. elegans gon-2 gene is required for the post-embryonic mitotic cell divisions of the gonadal precursor cells. A single major transcript of approximately 6.7 kb is derived from the gon-2 locus. This mRNA encodes a protein related to the TRP fami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7a5474cc880a549c35c82d260c5b0d
https://doi.org/10.1016/s0378-1119(01)00373-0

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CATP-6, a C. elegans ortholog of ATP13A2 PARK9, positively regulates GEM-1, an SLC16A transporter

Autor: Pamela J. Tieu, Eric J. Lambie, Barbara Conradt, Nadja Lebedeva, Diane L. Church

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77202 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a389c696de20052acdd0a4bb37475a
http://europepmc.org/articles/PMC3793975?pdf=render

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Tracheary element differentiation in Zinnia mesophyll cell cultures

Autor: Diane L. Church

Publikováno v: Plant Growth Regulation. 12:179-188

Mechanically isolated mesophyll cells of Zinnia elegans differentiate into tracheary elements (TEs) when cultured in a medium containing adequate auxin and cytokinin. Differentiation in this culture system is relatively synchronous, rapid (occuring w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e20ccb07b78721bfb18fe541145cad87
https://doi.org/10.1007/bf00027197

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Gem-1 encodes an SLC16 monocarboxylate transporter-related protein that functions in parallel to the gon-2 TRPM channel during gonad development in Caenorhabditis elegans

Autor: Diane L. Church, Benedict J. Kemp, Julia Hatzold, Eric J. Lambie, Barbara Conradt

Publikováno v: Genetics. 181(2)

The gon-2 gene of Caenorhabditis elegans encodes a TRPM cation channel required for gonadal cell divisions. In this article, we demonstrate that the gonadogenesis defects of gon-2 loss-of-function mutants (including a null allele) can be suppressed b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081b3187023d493310ab35b26d09506e
https://pubmed.ncbi.nlm.nih.gov/19087963

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Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development

Autor: Tim Schedl, Sudhir Nayak, Mitsue Ohmachi, Diane L. Church, Swathi Arur, Ross Francis, Min-Ho Lee, Eric J. Lambie

Publikováno v: Genetics. 177(4)

The raison d'etre of the germline is to produce oocytes and sperm that pass genetic material and cytoplasmic constituents to the next generation. To achieve this goal, many developmental processes must be executed and coordinated. ERK, the terminal M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d612b46f246ee28b27ae7fca132c706a
https://pubmed.ncbi.nlm.nih.gov/18073423

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C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation

Autor: Meera V. Sundaram, Diane L. Church, Tim Schedl, Eric J. Lambie, Mitsue Ohmachi, Christian E. Rocheleau

Publikováno v: Current biology : CB. 12(5)

Kinase Suppressor of Ras (KSR) is a conserved protein that positively regulates Ras signaling and may function as a scaffold for Raf, MEK, and ERK [1]. However, the precise role of KSR is not well understood, and some observations have suggested that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e92e9563f238b3182929fca5cadd5a
https://pubmed.ncbi.nlm.nih.gov/11882296

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Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans

Autor: Diane L. Church, Eric J. Lambie, Kun-Liang Guan

Publikováno v: Development (Cambridge, England). 121(8)

In the germline of Caenorhabditis elegans hermaphrodites, meiotic cell cycle progression occurs in spatially restricted regions. Immediately after leaving the distal mitotic region, germ cells enter meiosis and thereafter remain in the pachytene stag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b69bccc1dc3e95da1a2691676d8b21
https://pubmed.ncbi.nlm.nih.gov/7671816

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