Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Diane L Carlisle"'
Autor:
Tanisha Singh, Yuanyuan Jiao, Lisa M. Ferrando, Svitlana Yablonska, Fang Li, Emily C. Horoszko, David Lacomis, Robert M. Friedlander, Diane L. Carlisle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Amyotrophic lateral sclerosis is an adult-onset neurodegenerative disorder characterized by loss of motor neurons. Mitochondria are essential for neuronal survival but the developmental timing and mechanistic importance of mitochondrial dysf
Externí odkaz:
https://doaj.org/article/efa6a5cddeaf4ebbbd10ba1ac152d691
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105451- (2021)
In healthy neurons, a mitochondrial membrane potential gradient exists whereby membrane potential is highest in the soma and decreases with distance from the nucleus. Correspondingly, distal mitochondria have more oxidative damage and slower protein
Externí odkaz:
https://doaj.org/article/ad62b5d65e2647b5a0cc1d4de8339582
Autor:
Xiaomin Wang, Yalikun Suofu, Berkcan Akpinar, Sergei V. Baranov, Jinho Kim, Diane L. Carlisle, Yu Zhang, Robert M. Friedlander
Publikováno v:
Neurobiology of Disease, Vol 105, Iss , Pp 156-163 (2017)
Modulation of miRNA expression has been shown to be beneficial in the context of multiple diseases. The purpose of this study was to determine if an inhibitor of miR-337-3p is neuroprotective for hypoxic injury after tail vein injection. We evaluated
Externí odkaz:
https://doaj.org/article/d006a4077c2344ea9e3abf7979ae052d
Autor:
Robert M. Friedlander, Lisa M. Ferrando, Diane L. Carlisle, Yuanyuan Jiao, Fang Li, Emily C Horoszko, Svitlana Yablonska, Tanisha Singh, David Lacomis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Amyotrophic lateral sclerosis is an adult-onset neurodegenerative disorder characterized by loss of motor neurons. Mitochondria are essential for neuronal survival but the developmental timing and mechanistic importance of mitochondrial dysfunction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd838b19f2fbca5317d60c24d3bb961f
https://doaj.org/article/efa6a5cddeaf4ebbbd10ba1ac152d691
https://doaj.org/article/efa6a5cddeaf4ebbbd10ba1ac152d691
Autor:
Robert M Friedlander, Valentina Di Caro, Diane L Carlisle, Noel R Monks, Dani M Stoltzfus, Natasha L Bennett, Yalikun Suofu, Jinho Kim, Fang Li, Xiaomin Wang, Stacy M Yeh, Oxana V Baranov, Sergei V Baranov, Barry A Badeau, Jeremy W Gleaton, Gabriel A Cintrón-Rosado, Ryan R Dyer, Dietrich A Stephan, William R Mann, Sandra E Rojas-Caro
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc23b4cea503d97ccdec42e9e3f4535
https://doi.org/10.1136/jnnp-2022-ehdn.232
https://doi.org/10.1136/jnnp-2022-ehdn.232
Autor:
Yalikun Suofu, Abhishek Jauhari, Emilia S. Nirmala, William A. Mullins, Xiaomin Wang, Fang Li, Diane L. Carlisle, Robert M. Friedlander
Publikováno v:
Neuroscience letters. 795
Microglial activation is readily detected following cerebral ischemia/reperfusion-induced injury. Activated microglia polarize into either classic pro-inflammatory M1 or protective M2 microglia following ischemia/reperfusion-induced injury. Melatonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1885ccb5e2b43ea888ac24ebb8dfd5b
https://pubmed.ncbi.nlm.nih.gov/36586530
https://pubmed.ncbi.nlm.nih.gov/36586530
Autor:
Yi Zhang, Anna Cook, Jinho Kim, Sergei V. Baranov, Jiying Jiang, Karen Smith, Kerry Cormier, Erik Bennett, Robert P. Browser, Arthur L. Day, Diane L. Carlisle, Robert J. Ferrante, Xin Wang, Robert M. Friedlander
Publikováno v:
Neurobiology of Disease, Vol 55, Iss , Pp 26-35 (2013)
Caspase-mediated cell death contributes to the pathogenesis of motor neuron degeneration in the mutant SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS), along with other factors such as inflammation and oxidative damage. By scre
Externí odkaz:
https://doaj.org/article/7f0bbe0c7e0a4f158387a2cbcf9c8a86
Autor:
Diane L. Carlisle, Timothy M. Larkin, Svitlana Yablonska, Sergei V. Baranov, Donté A Stevens, Robert M. Friedlander, Jonathan S. Minden, Yuefang Chang, Mark E. Schurdak, Lisa M. Ferrando, Colleen E Strohlein, Xiaomin Wang, Nicolas K Khattar, Jinho Kim, Oxana V. Baranova, Anna Pyzel, Vinitha Ganesan, Ning Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 116:16593-16602
Mutant huntingtin (mHTT), the causative protein in Huntington’s disease (HD), associates with the translocase of mitochondrial inner membrane 23 (TIM23) complex, resulting in inhibition of synaptic mitochondrial protein import first detected in pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44da5ea30cbd61284e5f7973175e1f5a
https://doi.org/10.1073/pnas.1904101116
https://doi.org/10.1073/pnas.1904101116
Autor:
Samuel M. Poloyac, Svitlana Yablonska, Tanisha Singh, Xiaomin Wang, M. Beth Minnigh, Abhishek Jauhari, Fang Li, Robert M. Friedlander, Jinho Kim, Yalikun Suofu, Patrick J. Oberly, Diane L. Carlisle, Sergei V. Baranov
Publikováno v:
J Clin Invest
Chronic inflammation is a pathologic feature of neurodegeneration and aging; however, the mechanism regulating this process is not understood. Melatonin, an endogenous free radical scavenger synthesized by neuronal mitochondria, decreases with aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431577cf3c3f4cdc7b398bdb2745429a
https://europepmc.org/articles/PMC7260019/
https://europepmc.org/articles/PMC7260019/
Autor:
Yuefang Chang, Andrew J. Sedgewick, Panayiotis V. Benos, William R. Lariviere, Yin Zhao, Diane L. Carlisle, Brian T. Jankowitz, Lucia Stefaneanu, Robert M. Friedlander, Georgios A. Zenonos, Paul A. Gardner, William A. LaFramboise, Ellen M. Caparosa
Publikováno v:
Neurosurgery. 85:E284-E293
Background Many studies have explored molecular markers of carotid plaque development and vulnerability to rupture, usually having examined whole carotid plaques. However, there are regional differences in plaque morphology and known shear-related me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a826b7c32b881a6b83980782c65b15e
https://doi.org/10.1093/neuros/nyy470
https://doi.org/10.1093/neuros/nyy470