Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diane K. Gerken"'
Publikováno v:
Toxicologic Pathology. 35:657-664
Ma Huang (equivalent to 0, 12.5, 25, or 50 mg/kg ephedrine) or ephedrine (0, 6.25, 12.5, 25 mg/kg) were administered as one bolus oral dose to male F344 rats with and without caffeine. The herbal medicine Ma Huang (ephedra) in combination with caffei
Autor:
Molly Vallant, Gary A. Boorman, Edward K. Lobenhofer, Richard D. Irwin, David E. Malarkey, Pamela E. Blackshear, Joel S. Parker, Diane K. Gerken
Publikováno v:
Toxicological Sciences. 86:185-193
There is increasing use of transcriptional profiling in hepatotoxicity studies in the rat. Understanding hepatic gene expression changes over time is critical, since tissue collection may occur throughout the day. Furthermore, when comparing results
Autor:
Christopher J. Portier, Milton R. Hejtmancik, Patrick Hurban, Molly Vallant, Gary A. Boorman, Greg Travlos, Richard D. Irwin, April M. Brys, Diane K. Gerken, Edward K. Lobenhofer, Joel S. Parker
Publikováno v:
Toxicologic Pathology. 33:102-110
A new tool beginning to have wider application in toxicology studies is transcript profiling using microarrays. Microarrays provide an opportunity to directly compare transcript populations in the tissues of chemical-exposed and unexposed animals. Wh
Autor:
Mamta Behl, Susan A. Elmore, Milton R. Hejtmancik, David E. Malarkey, Rajendra S. Chhabra, Diane K. Gerken
Publikováno v:
Toxicology. 314(1)
Styrene Acrylonitrile (SAN) Trimer is a by-product in the production of acrylonitrile styrene plastics. Following a report of a childhood cancer cluster in the Toms River section of Dover Township, New Jersey, SAN Trimer was identified as one of the
Autor:
Diane K. Gerken, Ronald A. Herbert, Michael E. Wyde, Michelle J. Hooth, Minerva Mercado-Feliciano, Milton R. Hejtmancik
Publikováno v:
Cutaneous and ocular toxicology. 32(3)
Pyrogallol (CAS No. 87-66-1), a benzenetriol used historically as a hair dye and currently in a number of industrial applications, was nominated to the National Toxicology Program (NTP) for testing based on the lack of toxicity and carcinogenicity da