Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Diane J. Cousens"'
1
Increased Mitogenic and Decreased Contractile P2 Receptors in Smooth Muscle Cells by Shear Stress in Human Vessels With Intact Endothelium
Autor: Diane J. Cousens, Marie-Ange Watson, Lena Karlsson, Lingwei Wang, Sverker Jern, Maria Andersson, David Erlinge
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 23:1370-1376
Objective— We investigated the role of shear stress in regulating P2 receptors in human umbilical vein. Methods and Results— Using a novel, computerized, biomechanical perfusion model, parallel vessel segments were randomized to simultaneous perf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1dba9563195823f365a822f0e687bf
https://doi.org/10.1161/01.atv.0000080350.37408.5a
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2
Adenosine Nucleotides Acting at the Human P2Y1Receptor Stimulate Mitogen-activated Protein Kinases and Induce Apoptosis
Autor: Tina S. Lundahl, Lynda A. Sellers, Patrick P.A. Humphrey, Diane J. Cousens, Eric A. Barnard, Joseph Simon
Publikováno v: Journal of Biological Chemistry. 276:16379-16390
For the widely distributed P2Y receptors for nucleotides, the transductional and functional responses downstream of their coupling to G proteins are poorly characterized. Here we describe apoptotic induction and the associated differential stimulatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888206e55a244d9256fd02b920253276
https://doi.org/10.1074/jbc.m006617200
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3
Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein ?-subunit chimeras
Autor: Simon J. Dowell, Martina Marzioch, Malcolm S. Whiteway, Jeffrey J. Clare, Julia H. White, Andrew J. Brown, Marie-Ange Watson, Diane J. Cousens, Chris Paddon, Susan L. Dyos, M A Romanos, Chris Plumpton
Publikováno v: Yeast. 16:11-22
The expression of mammalian G protein coupled receptors (GPCRs) in S. cerevisiae provides a powerful assay system for functional analysis, ligand identification and pharmaceutical screening. However, relatively few receptors have been coupled to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775c4cc88a8131b9e1381ffa6b86f520
https://doi.org/10.1002/(sici)1097-0061(20000115)16:1<11::aid-yea502>3.0.co
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4
Modeling and solution structure probing of the HIV-1 TAR stem-loop
Autor: Andrew D. Critchley, Diane J. Cousens, I. Haneef, Peter G. Stockley
Publikováno v: Journal of molecular graphics. 11(2)
We present a model for the three-dimensional structure of the HIV TAR stem-loop,1 based on a modeling algorithm2 which makes use of the known X-ray coordinates of tRNAs to generate a model structure, which has then been tested experimentally in solut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d5c8d0a2dfd0419b26caa5b0534dca
https://pubmed.ncbi.nlm.nih.gov/8347568
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5
The Amidase Regulatory Gene (amiR) of Pseudomonas aeruginosa
Autor: Diane J. Cousens, Patricia H. Clarke, Robert Drew
Publikováno v: Microbiology. 133:2041-2052
SUMMARY: Recombinant plasmids carrying the amidase genes of Pseudomonas aeruginosa were used to study the genetic control of amidase synthesis in Escherichia coli and Pseudomonas aeruginosa. The amidase regulator gene, amiR, was found to lie about 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d624fc2b21a4274070efd31d922ea8cb
https://doi.org/10.1099/00221287-133-8-2041
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