Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Diane J Ordway"'
Autor:
Mark Schiebler, Karen Brown, Krisztina Hegyi, Sandra M Newton, Maurizio Renna, Lucy Hepburn, Catherine Klapholz, Sarah Coulter, Andres Obregón‐Henao, Marcela Henao Tamayo, Randall Basaraba, Beate Kampmann, Katherine M Henry, Joseph Burgon, Stephen A Renshaw, Angeleen Fleming, Robert R Kay, Karen E Anderson, Phillip T Hawkins, Diane J Ordway, David C Rubinsztein, Rodrigo Andres Floto
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 2, Pp 127-139 (2014)
Abstract Mycobacterium tuberculosis (MTB) remains a major challenge to global health made worse by the spread of multidrug resistance. We therefore examined whether stimulating intracellular killing of mycobacteria through pharmacological enhancement
Externí odkaz:
https://doaj.org/article/ada27d1f952241569b2948040684763a
Autor:
Xiyuan Bai, Nicole E Feldman, Kathryn Chmura, Alida R Ovrutsky, Wen-Lin Su, Laura Griffin, Dohun Pyeon, Mischa T McGibney, Matthew J Strand, Mari Numata, Seiji Murakami, Loretta Gaido, Jennifer R Honda, William H Kinney, Rebecca E Oberley-Deegan, Dennis R Voelker, Diane J Ordway, Edward D Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61925 (2013)
Nuclear factor-kappa B (NFκB) is a ubiquitous transcription factor that mediates pro-inflammatory responses required for host control of many microbial pathogens; on the other hand, NFκB has been implicated in the pathogenesis of other inflammatory
Externí odkaz:
https://doaj.org/article/50238e2d9ed1437aa6d2bdabacfc99d7
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80669 (2013)
Tuberculosis is one of the world's leading killers, stealing 1.4 million lives and causing 8.7 million new and relapsed infections in 2011. The only vaccine against tuberculosis is BCG which demonstrates variable efficacy in adults worldwide. Human i
Externí odkaz:
https://doaj.org/article/f0082fa4173a45f5939507a6c84e36ce
Autor:
Shaobin Shang, Sara Gibbs, Marcela Henao-Tamayo, Crystal A Shanley, Gerald McDonnell, Rafael Silva Duarte, Diane J Ordway, Mary Jackson
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24726 (2011)
Chronic pulmonary disease and skin/soft tissue infections due to non-tuberculous mycobacteria (NTM) of the Mycobacterium chelonae-abscessus-massiliense group is an emerging health problem worldwide. Moreover, the cure rate for the infections this gro
Externí odkaz:
https://doaj.org/article/40c39f63745c451aab09858e226f13e5
Autor:
Diane J Ordway, Marta S Martins, Leonor M Costa, Mónica S Freire, Maria J Arroz, Hazel M Dockrell, Fernando A Ventura
Publikováno v:
Acta Médica Portuguesa, Vol 18, Iss 1 (2005)
The study was designed to compare immune responses to Mycobacterium tuberculosis bacilli and antigens in healthy Portuguese subjects and pulmonary tuberculosis patients (TB), and to correlate immune status with clinical severity of tuberculosis disea
Externí odkaz:
https://doaj.org/article/107c1abedd7d42718139969583d61e2f
Autor:
Vinicius C. N. de Moura, Deepshikha Verma, Isobel Everall, Karen P. Brown, Juan M. Belardinelli, Crystal Shanley, Megan Stapleton, Julian Parkhill, R. Andres Floto, Diane J. Ordway, Mary Jackson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Chronic pulmonary infections caused by non-tuberculous mycobacteria of the Mycobacterium abscessus complex (MABSC) are emerging as a global health problem and pose a threat to susceptible individuals with structural lung disease such as cystic fibros
Externí odkaz:
https://doaj.org/article/4c82328718ca4ed19fb60efd80305910
Publikováno v:
Immunol Rev
Immunity against different Mycobacteria species targeting the lung requires distinctly different pulmonary immune responses for bacterial clearance. Many parameters of acquired and regulatory immune responses differ quantitatively and qualitatively f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81dcac7444ab820b04f9fbea1abba18
https://doi.org/10.1111/imr.12959
https://doi.org/10.1111/imr.12959
Autor:
Juan Manuel, Belardinelli, Deepshikha, Verma, Wei, Li, Charlotte, Avanzi, Crystal J, Wiersma, John T, Williams, Benjamin K, Johnson, Matthew, Zimmerman, Nicholas, Whittel, Bhanupriya, Angala, Han, Wang, Victoria, Jones, Véronique, Dartois, Vinicius C N, de Moura, Mercedes, Gonzalez-Juarrero, Camron, Pearce, Alan R, Schenkel, Kenneth C, Malcolm, Jerry A, Nick, Susan A, Charman, Timothy N C, Wells, Brendan K, Podell, Jonathan L, Vennerstrom, Diane J, Ordway, Robert B, Abramovitch, Mary, Jackson
Publikováno v:
Sci Transl Med
A search for alternative Mycobacterium abscessus treatments led to our interest in the two-component regulator DosRS which, in Mycobacterium tuberculosis, is required for the bacterium to establish a state of non-replicating, drug-tolerant persistenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72e6645796bf653c693bf6c1a571ce52
https://pubmed.ncbi.nlm.nih.gov/35196022
https://pubmed.ncbi.nlm.nih.gov/35196022
Autor:
Petra Selchow, Diane J. Ordway, Deepshikha Verma, Nicholas Whittel, Aline Petrig, Sven N. Hobbie, Erik C. Böttger, Peter Sander
Publikováno v:
Antimicrob Agents Chemother
Antibiotic therapy of infections caused by the emerging pathogen Mycobacterium abscessus is challenging due to the organism's inherent resistance to clinically available antimicrobials. The low bactericidal potency of currently available treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166aa7602af33389f2f20cfe9cc99abb
https://europepmc.org/articles/PMC8846310/
https://europepmc.org/articles/PMC8846310/
Autor:
R. Andres Floto, Julian Parkhill, Crystal A. Shanley, Karen Brown, Juan Manuel Belardinelli, Isobel Everall, Mary Jackson, Diane J. Ordway, Deepshikha Verma, Megan Stapleton, Vinicius Calado Nogueira de Moura
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Chronic pulmonary infections caused by non-tuberculous mycobacteria of the Mycobacterium abscessus complex (MABSC) are emerging as a global health problem and pose a threat to susceptible individuals with structural lung disease such as cystic fibros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed245db1e507772f1c5cdcc95d3218b5