Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Diane J Nugent"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55094 (2013)
We have engineered a transgenic mouse on a C57BL/6 background that bears a floxed Itga2 gene. The crossing of this mouse strain to transgenic mice expressing Cre recombinase driven by the megakaryocyte (MK)-specific Pf4 promoter permits the condition
Externí odkaz:
https://doaj.org/article/c9f4b98311de41c1aafd3b468cb9b9ed
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8743 (2010)
We have identified a cytosine-adenosine (CA) repeat length polymorphism in the 5'-regulatory region of the human integrin alpha2 gene ITGA2 that begins at -605. Our objective was to establish the contribution of this polymorphism to the regulation of
Externí odkaz:
https://doaj.org/article/3877c385d80d462b9c801a5c78f333fc
Autor:
Erna C. vanBalen, Brian O'Mahony, Marjon H. Cnossen, Gerard Dolan, Victor S. Blanchette, Kathelijn Fischer, Deborah Gue, Jamie O'Hara, Alfonso Iorio, Shannon Jackson, Barbara A. Konkle, Diane J. Nugent, Donna Coffin, Mark W. Skinner, Cees Smit, Alok Srivastava, Fred vanEenennaam, Johanna G. van derBom, Samantha C. Gouw
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 4, Pp n/a-n/a (2021)
Abstract Background Patient‐relevant health outcomes for persons with hemophilia should be identified and prioritized to optimize and individualize care for persons with hemophilia. Therefore, an international group of persons with hemophilia and m
Externí odkaz:
https://doaj.org/article/3175fb31b542464498c124912c75e4c5
Autor:
Kellie Bacon, Aprille Tongol, Bryan Lara, Chloe Knudsen-Robbins, Terence D. Sanger, Diane J. Nugent, Theodore W Heyming, John Schomberg, Janet Hoang
Publikováno v:
International Journal of Infectious Diseases, Vol 113, Iss, Pp 1-6 (2021)
International Journal of Infectious Diseases
International Journal of Infectious Diseases
Background: The durability of the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination remains unknown. The objective of this study was to evaluate a rapid SARS-CoV-2 IgM/IgG antibody detection kit as a qualitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f93c98d0a0a9eb1ec3a99733a5269c
http://www.sciencedirect.com/science/article/pii/S1201971221007724
http://www.sciencedirect.com/science/article/pii/S1201971221007724
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2302
Li-Fraumeni Syndrome (LFS) is an autosomal dominant disorder where an oncogenic TP53 germline mutation is inherited by offspring of a carrier parent. p53 is a key tumor suppressor regulating cell cycle arrest in response to DNA damage. Unexpectedly,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bc9b66de70f5d53efad9a9c9e0ac13
Autor:
Mark T. Reding, Judith Baker, Michael Recht, Miguel A. Escobar, Leonard A. Valentino, Joseph N Pugliese, Constance B Thibodeaux, Mark W. Skinner, Diane J. Nugent, Susan Karp, Michelle Rice, Regina Butler, Neil Frick, Kollet Koulianos, Susan Lattimore
Publikováno v:
Journal of Blood Medicine
Rare, chronic diseases such as hemophilia and other congenital coagulation disorders require coordinated delivery of services for optimal outcomes. Hemophilia Treatment Centers (HTCs) are specialized, multidisciplinary health-care centers providing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e773707621f0189473d59b8b1becb5a1
http://europepmc.org/articles/PMC8544265
http://europepmc.org/articles/PMC8544265
Autor:
Susanne Holzhauer, Diane J. Nugent, Thomas Kühne, Paul Imbach, Markus G. Seidel, Marc Michel, Andrea Heiri, Alexandra Schifferli
Publikováno v:
Blood Adv
Primary immune thrombocytopenia (ITP) in children is a diagnosis of exclusion, but cases of secondary ITP and nonimmune thrombocytopenia (non-IT) are generally difficult to recognize in a timely fashion. We describe a pediatric population with a revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acb66f7d770903b73addcef10b7ff24
https://doi.org/10.1182/bloodadvances.2020003004
https://doi.org/10.1182/bloodadvances.2020003004
Autor:
Maria Chitty Lopez, Victoria R. Dimitriades, Cathleen A. Collins, David Buchbinder, Diane J. Nugent, Morna J. Dorsey, Jolan E. Walter, Wan Yin Chan, Jennifer M. Puck, Jasjit Singh, Manish J. Butte
Publikováno v:
J Clin Immunol
Journal of clinical immunology, vol 41, iss 2
Journal of clinical immunology, vol 41, iss 2
Newborn screening efforts focusing on the quantification of T cell receptor excision circles (TRECs), as a biomarker for abnormal thymic production of T cells, have allowed for the identification and definitive treatment of severe combined immunodefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753ad3b50e6d465024f8ebf41084c4c5
https://doi.org/10.1007/s10875-020-00931-2
https://doi.org/10.1007/s10875-020-00931-2
Autor:
Diane J. Nugent, Kristin T Ansteatt, Michael D. Tarantino, Chanel J Unzicker, Marsha L Hurn, Oluwaseun Olaiya
Publikováno v:
Journal of Blood Medicine. 11:457-463
Chronic platelet disorders (CPD), including chronic immune thrombocytopenic purpura (cITP), thrombotic thrombocytopenic purpura (TTP) and platelet function disorders are among the most common bleeding disorders and are associated with morbidity and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4430014e7ac78064173e71106a252e7
https://doi.org/10.2147/jbm.s289390
https://doi.org/10.2147/jbm.s289390
Autor:
Robert B. Kelly, Michele Domico, Juliette L. Hunt, Negar Ashouri, Diane J. Nugent, Anthony C. McCanta
Publikováno v:
HeartRhythm Case Reports
HeartRhythm case reports, vol 6, iss 11
HeartRhythm case reports, vol 6, iss 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a4ee176622d94659a60f6bbf2e2e56
https://doi.org/10.1016/j.hrcr.2020.08.015
https://doi.org/10.1016/j.hrcr.2020.08.015