Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Diane J, Poole"'
Autor:
Jeffrey Schlom, William L. Dahut, Herbert Kotz, Seth M. Steinberg, James W. Hodge, Jack P. Higgins, Mary P. Pazdur, Jacquin L. Jones, Vittore Cereda, Cinzia Remondo, Diane J. Poole, Claudia Palena, Junko Yokokawa, Kwong-Yok Tsang, Philip M. Arlen, James L. Gulley
Supplementary Data from Pilot Study of Vaccination with Recombinant CEA-MUC-1-TRICOM Poxviral-Based Vaccines in Patients with Metastatic Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c8af7ecc80a59b46abf061226ce87d
https://doi.org/10.1158/1078-0432.22439665
https://doi.org/10.1158/1078-0432.22439665
Autor:
James L. Gulley, Jeffrey Schlom, William L. Dahut, Elizabeth C. Jones, Myrna Rauckhorst, Mary Pazdur, Seth M. Steinberg, Philip M. Arlen, Christopher R. Heery, Theresa Ferrara, Jacquin Jones, Caroline Jochems, Diane J. Poole, Ngar-Yee Huen, Ravi A. Madan, Kwong-Yok Tsang, Mahsa Mohebtash
Purpose: PANVAC is a recombinant poxviral vaccine that contains transgenes for MUC-1, CEA, and 3 T-cell costimulatory molecules. This study was conducted to obtain preliminary evidence of clinical response in metastatic breast and ovarian cancer pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fce3deba8bdd7c7796eecf66b09dab2
https://doi.org/10.1158/1078-0432.c.6519708.v1
https://doi.org/10.1158/1078-0432.c.6519708.v1
Autor:
Jeffrey Schlom, William L. Dahut, Herbert Kotz, Seth M. Steinberg, James W. Hodge, Jack P. Higgins, Mary P. Pazdur, Jacquin L. Jones, Vittore Cereda, Cinzia Remondo, Diane J. Poole, Claudia Palena, Junko Yokokawa, Kwong-Yok Tsang, Philip M. Arlen, James L. Gulley
Purpose: Poxviral vectors have a proven safety record and can be used to incorporate multiple transgenes. Prior clinical trials with poxviral vaccines have shown that immunologic tolerance to self-antigens can be broken. Carcinoembryonic antigen (CEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7595bd0013f69f6f354aaba2b0cfaa92
https://doi.org/10.1158/1078-0432.c.6517102
https://doi.org/10.1158/1078-0432.c.6517102
Autor:
James L. Gulley, Jeffrey Schlom, William L. Dahut, Elizabeth C. Jones, Myrna Rauckhorst, Mary Pazdur, Seth M. Steinberg, Philip M. Arlen, Christopher R. Heery, Theresa Ferrara, Jacquin Jones, Caroline Jochems, Diane J. Poole, Ngar-Yee Huen, Ravi A. Madan, Kwong-Yok Tsang, Mahsa Mohebtash
PDF file - 101K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00e37d504dbab49977694d736abf2e6
https://doi.org/10.1158/1078-0432.22443189
https://doi.org/10.1158/1078-0432.22443189
Autor:
Myrna Rauckhorst, Matteo Vergati, Howard L. Parnes, Philip M. Arlen, Seth M. Steinberg, Jeffrey Schlom, Mahsa Mohebtash, Ravi A. Madan, Diane J. Poole, William L. Dahut, James L. Gulley, John J. Wright, Kwong Y. Tsang
Publikováno v:
The Lancet Oncology. 13:501-508
Summary Background Therapeutic cancer vaccines have shown activity in metastatic castration-resistant prostate cancer (mCRPC), and methods are being assessed to enhance their efficacy. Ipilimumab is an antagonistic monoclonal antibody that binds cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410318a0ccd1a7fa454dab3e454919df
https://doi.org/10.1016/s1470-2045(12)70006-2
https://doi.org/10.1016/s1470-2045(12)70006-2
Autor:
Ravi A. Madan, Aradhana Kaushal, M. Kamrava, Diane J. Poole, Theresa A. Ferrara, Kesarwala Ah, William L. Dahut, Seth M. Steinberg, E. Lita, J. Schlom, James L. Gulley, Kwong Y. Tsang
Publikováno v:
Prostate Cancer and Prostatic Diseases. 15:289-295
Vaccine therapy in combination with radiation therapy may improve distant and/or local control in prostate cancer. We present long-term follow-up data on the secondary and exploratory endpoints of safety and biochemical failure, respectively, from pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce121254f4e6b370e5ac70e62530935b
https://doi.org/10.1038/pcan.2012.7
https://doi.org/10.1038/pcan.2012.7
Autor:
Kwong-Yok Tsang, Jeffrey Schlom, Ravi A. Madan, Elizabeth C. Jones, James L. Gulley, Mary Pazdur, Jacquin Jones, Theresa A. Ferrara, Philip M. Arlen, Ngar-Yee Huen, Diane J. Poole, Seth M. Steinberg, William L. Dahut, Caroline Jochems, Christopher R. Heery, Mahsa Mohebtash, Myrna Rauckhorst
Publikováno v:
Clinical Cancer Research. 17:7164-7173
Purpose: PANVAC is a recombinant poxviral vaccine that contains transgenes for MUC-1, CEA, and 3 T-cell costimulatory molecules. This study was conducted to obtain preliminary evidence of clinical response in metastatic breast and ovarian cancer pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c644d9ff6816a678e4afc7f1af8a86f1
https://doi.org/10.1158/1078-0432.ccr-11-0649
https://doi.org/10.1158/1078-0432.ccr-11-0649
New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy
Autor:
Diane J. Poole, Kwong Y. Tsang, Cinzia Remondo, Ira Pastan, Philip M. Arlen, Claudia Palena, James L. Gulley, Vittore Cereda, Jeffrey Schlom, Sudipto Das, Tapan K. Bera, Junko Yokokawa
Publikováno v:
Cancer Immunology, Immunotherapy. 59:63-71
New gene expressed in prostate (NGEP) is a prostate-specific gene encoding either a small cytoplasmic protein (NGEP-S) or a larger polytopic membrane protein (NGEP-L). NGEP-L expression is detectable only in prostate cancer, benign prostatic hyperpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88604ce2a5b05546ff247a4c31569aef
https://doi.org/10.1007/s00262-009-0723-6
https://doi.org/10.1007/s00262-009-0723-6
Autor:
James W. Hodge, Jacquin Jones, Jack P. Higgins, Claudia Palena, Cinzia Remondo, James L. Gulley, Seth M. Steinberg, Herbert L. Kotz, Mary Pazdur, Vittore Cereda, William L. Dahut, Junko Yokokawa, Philip M. Arlen, Kwong-Yok Tsang, Diane J. Poole, Jeffrey Schlom
Publikováno v:
Clinical Cancer Research. 14:3060-3069
Purpose: Poxviral vectors have a proven safety record and can be used to incorporate multiple transgenes. Prior clinical trials with poxviral vaccines have shown that immunologic tolerance to self-antigens can be broken. Carcinoembryonic antigen (CEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ad0f8865056da08f121d3c7e6b03a2
https://doi.org/10.1158/1078-0432.ccr-08-0126
https://doi.org/10.1158/1078-0432.ccr-08-0126
Publikováno v:
Gynecologic Oncology. 88:S97-S104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15154da96b020d5b929a64fdfe963eb8
https://doi.org/10.1006/gyno.2002.6694
https://doi.org/10.1006/gyno.2002.6694