Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diane Hawkins-Brown"'
Autor:
John T. Moore, Diane Hawkins-Brown, Bryan Goodwin, Jodi M. Maglich, Steven A. Kliewer, Catherine M. Stoltz
Publikováno v:
Molecular Pharmacology. 62:638-646
The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central roles in protecting the body against environmental chemicals (xenobiotics). PXR and CAR are activated by a wide range of xenobiotics and regulate cytochrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a8eb91b9d562e6f7111762b743fde0
https://doi.org/10.1124/mol.62.3.638
https://doi.org/10.1124/mol.62.3.638
Autor:
Bryan Goodwin, Kathleen K. Brown, Yaping Liu, John F. Reinhard, Diane Hawkins-Brown, Stacey A. Jones, Curtis D. Klaassen, Jeff L. Staudinger, Kathleen I. MacKenzie, Anne M. Latour, Timothy M. Willson, Beverly H. Koller, Steven A. Kliewer
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3369-3374
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which induce cytochrome P450 3A ( CYP3A ) expression and protect the body from harmful chemicals. In this study, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d6b55b46b0d039ba18a61afa3a2146
https://doi.org/10.1073/pnas.051551698
https://doi.org/10.1073/pnas.051551698
Publikováno v:
Reproduction. 86:493-500
Reciprocal embryo transfers amongst two inbred strains (C3HeB/FeJ and SWR/J) and their F1 cross (C3SWF1) were used to examine donor and recipient genotype and heterosis effects on survival and prenatal growth of mouse embryos. Among inbred strains, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161a3e78609396529bb016c5f0919a02
https://doi.org/10.1530/jrf.0.0860493
https://doi.org/10.1530/jrf.0.0860493
Autor:
M, Maglich Jodi, M, Stoltz Catherine, Bryan, Goodwin, Diane, Hawkins-Brown, T, Moore John, A, Kliewer Steven
Publikováno v:
Molecular Pharmacology; September 2002, Vol. 62 Issue: 3 p638-46, 9p
Publikováno v:
Genetics. 122(1)
Embryo transfers were used to demonstrate that the genotype of the mother providing the uterine developmental environment significantly influences postnatal growth and adult body size of her progeny. Irrespective of their own genotype, mouse embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb9e4dd398ac53c644451e759982948
https://pubmed.ncbi.nlm.nih.gov/2731729
https://pubmed.ncbi.nlm.nih.gov/2731729