Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Diane Hardej"'
Publikováno v:
Environmental Toxicology and Pharmacology. 99:104116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068c800798355ce3c167ec147c3e88a4
https://doi.org/10.1016/j.etap.2023.104116
https://doi.org/10.1016/j.etap.2023.104116
Autor:
Benjamin R, Kistinger, Diane, Hardej
Publikováno v:
Environmental Toxicology and Pharmacology. 92:103849
Mancozeb is a fungicide of the ethylene bisdithiocarbamate (EBDC) class complexed to the metals manganese and zinc. Nabam is the sodium salt of the EBDC backbone. The purpose of this study was to determine if these EBDC compounds alter essential meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3827575698be867dba2168e3e4a9469e
https://doi.org/10.1016/j.etap.2022.103849
https://doi.org/10.1016/j.etap.2022.103849
Autor:
Diane Hardej, Amanda Dhaneshwar
Publikováno v:
Environmental toxicology and pharmacology. 84
Ethylene bisdithiocarbamate pesticides, including Mancozeb (MZ), are used as fungicides. Effects of MZ on apoptosis induction and mitochondrial activity of HT-29 colon cells were investigated. MZ exposed cells exhibited blebbing and cellular membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baf75786d91ddef61dd96fc6d0db569
https://pubmed.ncbi.nlm.nih.gov/33592315
https://pubmed.ncbi.nlm.nih.gov/33592315
Autor:
Diane Hardej, Saif A. Alharthy
Publikováno v:
Environmental Toxicology and Pharmacology. 86:103652
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are members of perfluoroalkyl substances (PFAS). This study aimed to determine the protective role of Nrf2 against the toxicity of these agents. Nrf2-/- and wild-type astrocytes were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38240d1502d173dc080648e496b0dfe5
https://doi.org/10.1016/j.etap.2021.103652
https://doi.org/10.1016/j.etap.2021.103652
Publikováno v:
Environmental Toxicology and Pharmacology. 41:78-88
Previous studies in our laboratory have shown that ethylene bisdithiocarbamate (EBDC) fungicides Maneb and Mancozeb are equipotent gastrointestinal toxicants that produce cell loss and metal accumulation within HT-29 and Caco2 colon cells. Nabam, MnC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841299f221d83ec14b71e68abd389470
https://doi.org/10.1016/j.etap.2015.11.002
https://doi.org/10.1016/j.etap.2015.11.002
Autor:
Diane Hardej, Satyakam Singh, Shridhar S. Kulkarni, Tanaji T. Talele, Nikhil Khadtare, Charles R. Ashby
Publikováno v:
European Journal of Medicinal Chemistry. 45:5827-5832
A series of rhodanine compounds containing various substituents at the N3- and C5-positions were synthesized and their in vitro activity against a panel of clinically relevant MRSA strains was determined. The anti-MRSA activity of compounds 21 (MIC =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7be1b2f33f3ef010faed22ec3307b3
https://doi.org/10.1016/j.ejmech.2010.09.045
https://doi.org/10.1016/j.ejmech.2010.09.045
Publikováno v:
Experimental Lung Research. 36:94-100
As an alternative to conventional antibiotics, aerosolized recombinant human lysozyme (rhLZ) was used to treat experimentally induced pneumonia. Syrian hamsters were inoculated intratracheally with a nonmucoid strain of Pseudomonas aeruginosa (PA), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367cfcd708ee0c35016dfd49cc74ae4b
https://doi.org/10.3109/01902140903154608
https://doi.org/10.3109/01902140903154608
Publikováno v:
Food and Chemical Toxicology. 46:3664-3670
The present work has evaluated the role of lipopolysaccharide (LPS) stimulation and of TLR4 receptors on the cytotoxicity of resveratrol (RES), a polyphenolic stilbene component of red wine, in TLR4-bearing (i.e., RAW 264.7) and TLR4-deficient (i.e.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc5c364dc796c59704fbbfeae4754e1
https://doi.org/10.1016/j.fct.2008.09.043
https://doi.org/10.1016/j.fct.2008.09.043
Autor:
Blase Billack, Diane Hardej
Publikováno v:
Toxicology and Industrial Health. 23:209-221
Nitrogen mustards are vesicants capable of burning the skin, eyes and respiratory tract of exposed individuals. While generally less toxic than sulfur mustards, these compounds have the potential for use as chemical warfare agents. Presently, no anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3061b0068218a8944f459bdbbc5f69d
https://doi.org/10.1177/0748233707083541
https://doi.org/10.1177/0748233707083541
Autor:
Diane Hardej, Puneet Vij
Publikováno v:
Environmental toxicology and pharmacology. 43
The current study evaluated the potential of TeCl4 and DPDT to accumulate within cells and cause oxidative stress. HO-1, antioxidant gene expression and protein alterations were studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb52b36aaae65db86014ee673fb507d
https://pubmed.ncbi.nlm.nih.gov/27017383
https://pubmed.ncbi.nlm.nih.gov/27017383