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pro vyhledávání: '"Diane Ecklund"'
Autor:
Rosalind Ramsey-Goldman, Hee Kap Kang, Syamal K. Datta, Li Zhang, Ming Yi Chiang, Diane Ecklund
Publikováno v:
The Journal of Immunology. 188:5970-5980
In search of autoantigen-presenting cells that prime the pathogenic autoantibody-inducing Th cells of lupus, we found that CD41+CD151+ cells among Lineage– (Lin–) CD117+ (c-Kit+) CX3CR1– splenocytes depleted of known APCs were most proficient i
Publikováno v:
Journal of Clinical Immunology. 31:379-394
Tolerance therapy with nucleosomal histone peptides H4(71-94), H4(16-39), or H1'(22-42) controls disease in lupus-prone SNF1 mice. It would be clinically important to determine whether a cocktail of the above epitopes would be superior. Herein, we fo
Publikováno v:
Arthritis Research & Therapy
Introduction Lupus patients need alternatives to steroids and cytotoxic drugs. We recently found that apigenin, a non-mutagenic dietary flavonoid, can sensitize recurrently activated, normal human T cells to apoptosis by inhibiting nuclear factor-kap