Výsledky vyhledávání - "Diane E. Gunson"

Acute Toxicity of Vildagliptin

Autor: Diane E. Gunson, Phil Bentley, Michael Hayes, Elizabeth Skuba, Peter Hoffmann, Dan Lapadula, Steve Busch, Lori Martin, Michael Keselica

Publikováno v: Toxicologic Pathology. 45:76-83

This article describes acute toxicity data in cynomolgus monkeys following oral treatment with vildagliptin, a dipeptidyl peptidase-4 inhibitor. Acute toxicity symptoms in cynomolgus monkeys include edema formation of the extremities, tails, and face

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::369189ef5e13c009b695870c8fc1b07e
https://doi.org/10.1177/0192623316672944

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Bone and Joints

Autor: Diane E. Gunson, Aurore Varela, Kathryn E. Gropp

The skeleton fulfills several needs in an animal. It serves as a scaffold on which muscles can act to produce locomotion, provides protection for vital structures, supplies an internal source for minerals, and harbors an environment that supports hem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a343b9463a32a3a351ecf67f9e5dc1d7
https://doi.org/10.1016/b978-0-12-809841-7.00024-1

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No Bones About It: The Challenges and Rewards of Osteopathology

Autor: Diane E. Gunson, Kathryn E. Gropp, Cathy S. Carlson

Publikováno v: Veterinary pathology. 52(5)

When examining bones and joints, toxicologic pathologists and those working on experimental models have the advantage of being able to examine sections from an equal number of agematched control animals that are sectioned in the same plane as treated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96830c39080c9e9282e9f9e1c999afa0
https://pubmed.ncbi.nlm.nih.gov/26290180

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Strong poison revisited

Autor: Ingrid J. Pickering, Roger C. Prince, Raymond J. Turner, Jürgen Gailer, Diane E. Gunson, Graham N. George

Publikováno v: Journal of Inorganic Biochemistry. 101:1891-1893

Selenium in the form of selenocysteine plays an essential role in a number of proteins, but its role in non-enzymatic biochemistry is also important. In this short review we discuss the interactions between inorganic selenium, arsenic and mercury und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e486bbcc62e25f2bf7dca1e277335e5
https://doi.org/10.1016/j.jinorgbio.2007.06.008

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Functional and morphological characterization of neuropathy induced with 5-Lipoxygenase inhibitor CGS 21595

Autor: W. O. Iverson, V. M. Traina, Georg Krinke, M.H. Vonau, W. Classen, Diane E. Gunson

Publikováno v: Experimental and Toxicologic Pathology. 46:119-125

Summary Peripheral toxic neuropathy induced in rats with a 5-lipoxygenase inhibitor CGS 21 595 was characterized using special functional tests and pathological procedures. Functional tests included measurement of grip strength, landing foot splay, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84cd11c5ac8469b96c4794654cbb0d2
https://doi.org/10.1016/s0940-2993(11)80038-2

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