Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Diane E Peters"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004470 (2014)
The development of eutherian mammalian embryos is critically dependent on the selective bi-directional transport of molecules across the placenta. Here, we uncover two independent and partially redundant protease signaling pathways that include the m
Externí odkaz:
https://doaj.org/article/d640fb5de5074cefa0ceb6170e674ca5
Autor:
Jeffrey M Schafer, Diane E Peters, Thomas Morley, Shihui Liu, Alfredo A Molinolo, Stephen H Leppla, Thomas H Bugge
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20532 (2011)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Although considerable progress has been made in elucidating the etiology of the disease, the prognosis for individuals diagnosed with HNSCC remains poor, undersc
Externí odkaz:
https://doaj.org/article/f9749c0468314d60b6c37af1e097329d
Autor:
Rana Rais, Kathryn M. Lemberg, Lukáš Tenora, Matthew L. Arwood, Arindom Pal, Jesse Alt, Ying Wu, Jenny Lam, Joanna Marie H. Aguilar, Liang Zhao, Diane E. Peters, Carolyn Tallon, Rajeev Pandey, Ajit G. Thomas, Ranjeet P. Dash, Tanguy Seiwert, Pavel Majer, Robert D. Leone, Jonathan D. Powell, Barbara S. Slusher
Publikováno v:
Science advances. 8(46)
6-Diazo-5-oxo- l -norleucine (DON) is a glutamine antagonist that suppresses cancer cell metabolism but concurrently enhances the metabolic fitness of tumor CD8 + T cells. DON showed promising efficacy in clinical trials; however, its development was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f07fb35c5ea7c8da0c169f4eebf5b9
https://pubmed.ncbi.nlm.nih.gov/36383674
https://pubmed.ncbi.nlm.nih.gov/36383674
A Novel Oral Glutamate Carboxypeptidase II Inhibitor for the Treatment of Inflammatory Bowel Disease
Autor:
Manisha Pradhan, Diane E. Peters, Lauren D. Norris, Ajit G. Thomas, Rana Rais, Barbara S. Slusher
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e02da2f0cd5059bf9deb3146d79dae77
https://doi.org/10.1096/fasebj.2022.36.s1.r3089
https://doi.org/10.1096/fasebj.2022.36.s1.r3089
Autor:
Diane E. Peters, Lauren Norris, Lukáš Tenora, Ivan Šnajdr, Xiaolei Zhu, Shinji Sakamoto, Ajit G. Thomas, Pavel Majer, Rana Rais, Barbara Slusher
Publikováno v:
Gastroenterology. 162:S-404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe3d804031c09d368bfcff4339e16c07
https://doi.org/10.1016/s0016-5085(22)60957-0
https://doi.org/10.1016/s0016-5085(22)60957-0
Autor:
Ashley T. Davis, Diane E. Peters, Manish S. Bharadwaj, Andre C. LeGrand, Kylie Kavanagh, Anthony J.A. Molina
Publikováno v:
Obesity. 25:689-696
Objective Obesity exists with and without accompanying cardiometabolic disease, termed metabolically unhealthy obesity (MUO) and healthy obesity (MHO), respectively. Underlying differences in the ability of subcutaneous (SQ) fat to respond to nutrien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f2c3674f0ce06f30a96f1787aabfcb3
https://doi.org/10.1002/oby.21762
https://doi.org/10.1002/oby.21762
Publikováno v:
Crohn's & Colitis 360. 1
BackgroundDextran sodium sulfate (DSS)-induced colitis is the most commonly used mouse model of inflammatory bowel disease (IBD) due to its acute nature, reproducibility, and phenotypic overlap with human disease. Following an unexpected and sharp de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9234c34651de9290f2ea7518cbf259ac
https://doi.org/10.1093/crocol/otz030
https://doi.org/10.1093/crocol/otz030
Autor:
Kylie, Kavanagh, Ashley T, Davis, Diane E, Peters, Andre C, LeGrand, Manish S, Bharadwaj, Anthony J A, Molina
Publikováno v:
Obesity (Silver Spring, Md.). 25(4)
Obesity exists with and without accompanying cardiometabolic disease, termed metabolically unhealthy obesity (MUO) and healthy obesity (MHO), respectively. Underlying differences in the ability of subcutaneous (SQ) fat to respond to nutrient excess a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ff01c1a9057d3e25daeee8121f90210
https://pubmed.ncbi.nlm.nih.gov/28349666
https://pubmed.ncbi.nlm.nih.gov/28349666
Publikováno v:
Development.
The membrane-anchored serine proteases prostasin (PRSS8) and matriptase (ST14) initiate a cell surface proteolytic pathway essential for epithelial function. Mice expressing only catalytically inactive prostasin are viable, unlike prostasin null mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a52ec07bf80bf12262f74e051c861ab
https://doi.org/10.1242/dev.137968
https://doi.org/10.1242/dev.137968
Autor:
James L. Sudmeier, William W. Bachovchin, Youhua Li, Sarah E. Healey, Wengen Wu, Diane E. Peters, Amrita K. Chiluwal, Jack H. Lai, Yuhong Zhou, Yuxin Liu, Beth A. Connolly, Zhiping Jin, Matthew T. Dimare, Hlaing Hlaing Maw, David G. Sanford
Publikováno v:
Journal of Medicinal Chemistry. 51:6005-6013
Dipeptidyl peptidase IV (DPP-IV; E.C. 3.4.14.5), a serine protease that degrades the incretin hormones GLP-1 and GIP, is now a validated target for the treatment of type 2 diabetes. Dipeptide boronic acids, among the first, and still among the most p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba21303579948c1d60127e4e86a641fb
https://doi.org/10.1021/jm800390n
https://doi.org/10.1021/jm800390n