Výsledky vyhledávání - "Diane Dunham"

Akademický článek

A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells

Autor: Kathrin Balz, Magali Grange, Uta Pegel, Zain A. Karamya, Marielle Mello, Xiaoying Zhou, Thilo Berger, Konstantin Bloch, Diane Dunham, Sharon Chinthrajah, Kari Nadeau, Hervé Luche, Chrysanthi Skevaki

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)

Understanding antigen-specific T-cell responses, for example, following virus infections or allergen exposure, is of high relevance for the development of vaccines and therapeutics. We aimed on optimizing immunophenotyping of T cells after antigen st

Externí odkaz: https://doaj.org/article/cd666241a2b54fa2b38d3d9aa950af30

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Akademický článek

Mass cytometry analysis of blood from peanut-sensitized tolerant and clinically allergic infants

Autor: Amanda R. Tursi, Nicholas K. Saba, Diane Dunham, Monali Manohar, Rachel L. Peters, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau, Melanie R. Neeland, Sandra Andorf

Publikováno v: Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)

Measurement(s) expression profiling Technology Type(s) cytometry time of flight assay Sample Characteristic - Organism Homo sapiens Sample Characteristic - Location Australia

Externí odkaz: https://doaj.org/article/597c792267ea43529751aaebfe2bdae3

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Akademický článek

CD8+ T cell differentiation status correlates with the feasibility of sustained unresponsiveness following oral immunotherapy

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Oral immunotherapy (OIT) clinical trials have helped a subset of participants achieve sustained unresponsiveness (SU) to the cognate allergen. Here the authors analyse immune cells from participants from one peanut OIT trial and show that CD8+ T cell

Externí odkaz: https://doaj.org/article/f3d3643e782c428e859a1f49273bc85c

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Akademický článek

Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life

Autor: Melanie R. Neeland, Sandra Andorf, Monali Manohar, Diane Dunham, Shu-Chen Lyu, Thanh D. Dang, Rachel L. Peters, Kirsten P. Perrett, Mimi L. K. Tang, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and

Externí odkaz: https://doaj.org/article/966c4c38a8dd4e93886f0419ac4fec6a

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