Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Diane Delaroche"'
1
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes
Autor: Diane Delaroche, E C Vanzela, Fernanda Ortis, Henrik B. Mortensen, Lotte B Nielsen, Alessandra K Cardozo, Joachim Størling, Geert van Loo, Leen Catrysse, Makiko Fukaya, Rudi Beyaert, Flemming Pociot, Marie Louise Max M.L. Andersen, Caroline Brorsson, Kira Meyerovich
Publikováno v: Molecular Endocrinology. 30:48-61
Activation of the transcription factor nuclear factor kappa B (NFkB) contributes to β-cell death in type 1 diabetes (T1D). Genome-wide association studies have identified the gene TNF-induced protein 3 (TNFAIP3), encoding for the zinc finger protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debff7b766cdfe4ae3f3b9d6495bfcb8
https://doi.org/10.1210/me.2015-1176
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2
The Two NK-1 Binding Sites Correspond to Distinct, Independent, and Non-Interconvertible Receptor Conformational States As Confirmed by Plasmon-Waveguide Resonance Spectroscopy
Autor: Bernard Mouillac, Sandrine Sagan, Victor J. Hruby, Diane Delaroche, Isabel D. Alves, Solange Lavielle, Gordon Tollin, Zdzislaw Salamon
Publikováno v: Biochemistry
Biochemistry, 2006, 45, pp.5309-5318
Biochemistry, American Chemical Society, 2006, 45, pp.5309-5318
HAL
Two nonstoichiometric ligand binding sites have been previously reported for the NK-1 receptor, with the use of classical methods (radioligand binding and second messenger assays). The most populated (major, NK-1M) binding site binds substance P (SP)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882512498d1b343895811021654ae95
https://doi.org/10.1021/bi052586d
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3
Further Studies of the Norditerpene (+)-Harringtonolide Isolated fromCephalotaxus harringtoniavar.drupacea: Absolute Configuration, Cytotoxic and Antifungal Activities
Autor: Bastien Nay, Akino Jossang, Julie Nguyen-Pouplin, Bernard Bodo, Diane Delaroche, Laurent Evanno, Patrick Herson, Mannan Seuleiman
Publikováno v: Planta Medica. 74:870-872
Harringtonolide (= hainanolide) is a complex polycyclic fused norditerpene isolated from CEPHALOTAXUS HARRINGTONIA var. DRUPACEA. In spite of its appealing biological properties - we measured an IC (50) of 43 nM on KB cells and a significant antifung
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0be2ccb11e4cdbaf48f51cf2bff28f
https://doi.org/10.1055/s-2008-1074546
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4
Cardiac ATP-sensitive K+ channel associates with the glycolytic enzyme complex
Autor: Brian Malester, Miyoun Hong, Eirini Kefaloyianni, Li Bao, Thomas A. Neubert, Diane Delaroche, William A. Coetzee
Being gated by high-energy nucleotides, cardiac ATP-sensitive potassium (KATP) channels are exquisitely sensitive to changes in cellular energy metabolism. An emerging view is that proteins associated with the KATP channel provide an additional layer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bede2d462fc543b81db41d21839f33
https://europepmc.org/articles/PMC3114533/
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6
Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts
Autor: Gérard Chassaing, François-Xavier Cantrelle, Laurent Blanchoin, Sandrine Sagan, Diane Delaroche, Solange Lavielle, Carine van Heijenoort, Eric Guittet, Christian Auclair, Chen-Yu Jiao, Frederic Subra
Publikováno v: Journal of Biological Chemistry 10 (285), 7712-21. (2010)
Journal of Biological Chemistry
Journal of Biological Chemistry, 2010, 285 (10), pp.7712-21. ⟨10.1074/jbc.M109.045872⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (10), pp.7712-21. ⟨10.1074/jbc.M109.045872⟩
2010025; International audience; Cell-penetrating peptides can cross cell membranes and are commonly seen as biologically inert molecules. However, we found that some cell-penetrating peptides could remodel actin cytoskeleton in oncogene-transformed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c410889f319cd546c93bf768303a59
https://pubmed.ncbi.nlm.nih.gov/20037163
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7
Translocation and endocytosis for cell-penetrating peptide internalization
Autor: Gérard Chassaing, Diane Delaroche, Isabel D. Alves, Sandrine Sagan, Chen-Yu Jiao, Fabienne Burlina
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 ((49):), pp.33957-65. ⟨10.1074/jbc.M109.056309⟩
Journal of Biological Chemistry, 2009, 284 ((49):), pp.33957-65. ⟨10.1074/jbc.M109.056309⟩
International audience; Cell-penetrating peptides (CPPs) share the property of cellular internalization. The question of how these peptides reach the cytoplasm of cells is still widely debated. Herein, we have used a mass spectrometry-based method th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2048a2887c42937608bfac097b635cc
https://hal.archives-ouvertes.fr/hal-00627026
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8
Cell-surface thiols affect cell entry of disulfide-conjugated peptides
Autor: Alain Joliot, Diane Delaroche, Solange Lavielle, Fabienne Burlina, Edmond Dupont, Sandrine Sagan, Gérard Chassaing, Soline Aubry
Publikováno v: FASEB Journal
FASEB Journal, 2009, 23 ((9)), pp.2956-67. ⟨10.1096/fj.08-127563⟩
International audience; Cell-penetrating peptides (CPPs) can cross the cell membrane and are widely used to deliver bioactive cargoes inside cells. The cargo and the CPP are often conjugated through a disulfide bridge with the common acceptation that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c82a7c4eb8673b802dfa0897ba5d489
https://hal.science/hal-00627354
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9
[Tracking Trojan peptides in cells]
Autor: Sandrine, Sagan, Fabienne, Burlina, Diane, Delaroche, Baptiste, Aussedat, Soline, Aubry, Gérard, Bolbach, Solange, Lavielle, Gérard, Chassaing
Publikováno v: Journal de la Societe de biologie. 200(3)
Trojan peptides or cell-penetrating peptides (CPP) are natural or designed peptides identified as cellular membrane-crossing molecules, in particular through their potency to vehiculate various kinds of compounds to the cytoplasm and nucleus of livin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c19a535ebc42290b03b2f765b1c5b83d
https://pubmed.ncbi.nlm.nih.gov/17417135
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