Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Diane D. Petrone"'
Autor:
David M. Knight, Jennifer L. Luongo, Allison Oberholtzer, Diane D. Petrone, Tam Susan H, Omid Vafa, Randall J. Brezski, Robert Jordan, Gordon E. Powers, Mary Ryan
Publikováno v:
Proceedings of the National Academy of Sciences. 106:17864-17869
The successful elimination of pathogenic cells and microorganisms by the humoral immune system relies on effective interactions between host immunoglobulins and Fcγ receptors on effector cells, in addition to the complement system. Essential Ig moti
Autor:
Degang Zhong, Albert Schmidt, Robert Jordan, Susan H. Tam, David M. Knight, Marian Kruszynski, Diane D. Petrone, Mary Ryan, Randall J. Brezski, Brian Whitaker, Jennifer L. Luongo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 181(5)
A number of proteases of potential importance to human physiology possess the ability to selectively degrade and inactivate Igs. Proteolytic cleavage within and near the hinge domain of human IgG1 yielded products including Fab and F(ab′)2 possessi
Publikováno v:
Molecular immunology. 45(7)
A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, infl
Autor:
Brezski RJ; Biologics Research, Centocor R&D Inc., Radnor, PA 19087, USA. rbrezski@its.jnj.com, Vafa O, Petrone D, Tam SH, Powers G, Ryan MH, Luongo JL, Oberholtzer A, Knight DM, Jordan RE
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Oct 20; Vol. 106 (42), pp. 17864-9. Date of Electronic Publication: 2009 Oct 07.
Autor:
Brezski RJ; Discovery Research, Centocor R&D Inc., Radnor, PA 19087, USA. rbrezski@cntus.jnj.com, Luongo JL, Petrone D, Ryan MH, Zhong D, Tam SH, Schmidt AP, Kruszynski M, Whitaker BP, Knight DM, Jordan RE
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2008 Sep 01; Vol. 181 (5), pp. 3183-92.