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pro vyhledávání: '"Diane Crombie"'
Autor:
Michael G. Johnson, Mark E. Goldman, Diane Crombie, Bender Steven Lee, Dale E. Mais, Luc J. Farmer, Ming-Wei Wang, Todd K. Jones, Lawrence G. Hamann
Publikováno v:
Journal of Medicinal Chemistry. 39:1778-1789
A novel class of nonsteroidal progesterone receptor antagonists has been synthesized and was shown to exhibit moderate binding affinity for hPR-A, the ability to inhibit the transcriptional activity of human progesterone receptor (hPR) in cell-based