Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diane C. Waters"'
Publikováno v:
Journal of Neuroimmunology. 51:101-108
Functional NK-1 (substance P) receptors have been demonstrated previously on astrocytes from primary newborn rat brain cultures and human astrocytoma cells lines by specific [125I]-Bolton Hunter substance P (SP) binding and by SP-induced phosphoinosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557314ed2bd5006ec5b957f32b4a4294
https://doi.org/10.1016/0165-5728(94)90134-1
https://doi.org/10.1016/0165-5728(94)90134-1
Autor:
Bruce D. Gitter, Steven S. Y. Cho, Diane C. Waters, Donald R. Gehlert, Thomas Alan Crowell, Brian Stephen Muehl, Penny G. Threlkeld, Kirk W. Johnson, J. H. Krushinski, Karen Lynn Lobb, Robert F. Bruns, Philip Arthur Hipskind, Domenico Regoli, Lee A. Phebus, Nixon James Arthur, Smriti Iyengar, J. Jeffry Howbert, Dominic L. Li, Foreman Mark Mortensen, Norman R. Mason, Rosa Maria A. Simmons
Publikováno v:
ChemInform. 27
Early structure−activity studies on racemic tryptophan ester and amide NK-1 antagonists 5−7 led to the discovery that the potency of the series could be markedly increased by moving the carbonyl function in these molecules to an off-chain positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d4b6978086b543b61febe41890ebd9
https://doi.org/10.1002/chin.199621130
https://doi.org/10.1002/chin.199621130
Autor:
N. Rouissi, J. Jeffry Howbert, Diane C. Waters, Bruce D. Gitter, Domenico Regoli, Nixon James Arthur
Publikováno v:
Biochemical and Biophysical Research Communications. 176:894-901
Two members of a new class of non-peptide antagonists of substance P, (+-)-cis-3-(2-methoxybenzylamino)-2-benzhydrylquinuclidine [(+/-)-CP-96,345; I] and (+-)-cis-3-(2-chlorobenzylamino)-2-benzhydrylquinuclidine [II], were tested for their ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896cc0b87e86347aadf04522c5788ede
https://doi.org/10.1016/s0006-291x(05)80270-0
https://doi.org/10.1016/s0006-291x(05)80270-0
Autor:
Patrick C. May, Paula M. Robison, Gerald W. Becker, Diane C. Waters, Jennifer S. Small, Bruce D. Gitter, Linda K. Simmons
Publikováno v:
Neurobiology of Aging. 13:605-607
beta A4 peptide (beta AP) accumulates in amyloid plaques of Alzheimer's disease and may contribute to neuronal degeneration. Conflicting observations have been reported regarding the direct in vitro and in vivo neurotoxicity of beta AP. We have asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e210cfe2fc0da2389ce2f58bb2fcca
https://doi.org/10.1016/0197-4580(92)90064-5
https://doi.org/10.1016/0197-4580(92)90064-5
Autor:
Steven S. Y. Cho, Penny G. Threlkeld, Nixon James Arthur, Robert F. Bruns, Lee A. Phebus, Thomas Alan Crowell, Karen Lynn Lobb, Kirk W. Johnson, Donald R. Gehlert, Diane C. Waters, Bruce D. Gitter, Brian Stephen Muehl, J. H. Krushinski, Norman R. Mason, Rosa Maria A. Simmons, Domenico Regoli, J. Jeffry Howbert, Dominic L. Li, Foreman Mark Mortensen, Smriti Iyengar, Philip Arthur Hipskind
Publikováno v:
Journal of medicinal chemistry. 39(3)
Early structure-activity studies on racemic tryptophan ester and amide NK-1 antagonists 5-7 led to the discovery that the potency of the series could be markedly increased by moving the carbonyl function in these molecules to an off-chain position as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e905dd4cdd9b11a6c3ff4b2cc709422
https://pubmed.ncbi.nlm.nih.gov/8576917
https://pubmed.ncbi.nlm.nih.gov/8576917
Autor:
Bruce D. Gitter, Penny G. Threlkeld, Diane C. Waters, Robert F. Bruns, Anne M. Lovelace, Ken Matsumoto
Publikováno v:
European journal of pharmacology. 289(3)
The immunosuppressive cyclic undecapeptide, cyclosporin A, inhibited the binding of [125I]substance P to tachykinin NK1 receptors expressed by human IM-9 lymphoblastoid cells, U-373 MG human astrocytoma cells and guinea pig lung parenchyma with IC50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3838cc5f08b2fb4eac066e8b90e9a51
https://pubmed.ncbi.nlm.nih.gov/7556412
https://pubmed.ncbi.nlm.nih.gov/7556412
Autor:
Nixon James Arthur, J. Jeffry Howbert, Bruce D. Gitter, Robert F. Bruns, Diane C. Waters, Norman R. Mason
Publikováno v:
European journal of pharmacology. 197(2-3)
In the present study, affinities of (±)-CP-96,345 and analogs in [ 125 I]SP binding were determined in various tissues derived from several species. The resulting IC 50 values segregate into discrete groups according to species rather than tissue, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84d7e919337b434028fb5960a28fd9d
https://pubmed.ncbi.nlm.nih.gov/1717291
https://pubmed.ncbi.nlm.nih.gov/1717291
Autor:
Beverly Ketel, Marcia A. Miller, J. Thomas Hjelle, Barbara T. Golinska, Veronika Burmeister, Robert C. Caughey, Diane C. Waters, Phillip J. Olsson, Kevin R. Steidley, McCarroll Dr, Richard B. Prior
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 15(2)
Renal cystic epithelia and peritoneal mesothelia from two humans with autosomal recessive polycystic kidney disease (ARPKD) were grown in culture. Cystic epithelial and mesothelial cells formed continuous monolayers in vitro. By electron microscopy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4783c036cf4ceec622c6fd7e239ef6
https://pubmed.ncbi.nlm.nih.gov/2154094
https://pubmed.ncbi.nlm.nih.gov/2154094
Publikováno v:
Regulatory Peptides. 37:S62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1deac64fdd9af22fbd57c211d30e6a3e
https://doi.org/10.1016/0167-0115(92)90917-j
https://doi.org/10.1016/0167-0115(92)90917-j