Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Diane C Saunders"'
Autor:
Yicheng Tao, Fan Feng, Xin Luo, Conrad V Reihsmann, Alexander L Hopkirk, Jean-Philippe Cartailler, Marcela Brissova, Stephen C J Parker, Diane C Saunders, Jie Liu
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012344 (2024)
Recent studies show that cellular neighborhoods play an important role in evolving biological events such as cancer and diabetes. Therefore, it is critical to accurately and efficiently identify cellular neighborhoods from spatially-resolved single-c
Externí odkaz:
https://doaj.org/article/fa5d8a4580c940c98d6914fa30f9c20e
Autor:
Diane C. Saunders, Kristie I. Aamodt, Tiffany M. Richardson, Alexander J. Hopkirk, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, David K. Flaherty, Nripesh Prasad, Shawn E. Levy, Alvin C. Powers, Marcela Brissova
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Endogenous β cell regeneration could alleviate diabetes, but proliferative stimuli within the islet microenvironment are incompletely understood. We previously found that β cell recovery following hypervascularization-induced β cell loss
Externí odkaz:
https://doaj.org/article/9fc6488438814df2a6871457cb867bcb
Autor:
John S. Kaddis, Layla Rouse, Audrey V. Parent, Diane C. Saunders, Anath Shalev, Cherie L. Stabler, Doris A. Stoffers, Bridget K. Wagner, Joyce C. Niland
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101283- (2021)
Externí odkaz:
https://doaj.org/article/4b11df8c757349c58bcb1ec2250baff0
Autor:
Shristi Shrestha, Diane C. Saunders, John T. Walker, Joan Camunas-Soler, Xiao-Qing Dai, Rachana Haliyur, Radhika Aramandla, Greg Poffenberger, Nripesh Prasad, Rita Bottino, Roland Stein, Jean-Philippe Cartailler, Stephen C.J. Parker, Patrick E. MacDonald, Shawn E. Levy, Alvin C. Powers, Marcela Brissova
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Islet-enriched transcription factors (TFs) exert broad control over cellular processes in pancreatic α and β cells, and changes in their expression are associated with developmental state and diabetes. However, the implications of heterogeneity in
Externí odkaz:
https://doaj.org/article/a176612b370447eeb2aad97352fda235
Autor:
Diane C. Saunders, James Messmer, Irina Kusmartseva, Maria L. Beery, Mingder Yang, Mark A. Atkinson, Alvin C. Powers, Jean-Philippe Cartailler, Marcela Brissova
Publikováno v:
Patterns, Vol 1, Iss 8, Pp 100120- (2020)
Summary: Human tissue phenotyping generates complex spatial information from numerous imaging modalities, yet images typically become static figures for publication, and original data and metadata are rarely available. While comprehensive image maps
Externí odkaz:
https://doaj.org/article/e6c31d07b3cc4675ac3573e41496852b
Publikováno v:
Journal of Endocrinology.
In commemoration of 100 years since the discovery of glucagon, we review current knowledge about the human α cell. Alpha cells make up 30-40% of human islet endocrine cells and play a major role in regulating whole-body glucose homeostasis, largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57579cbd54ffa0eacbff5818675bad56
https://doi.org/10.1530/joe-22-0298
https://doi.org/10.1530/joe-22-0298
Autor:
Aanchal Mongia, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi
Cellular composition and anatomical organization influence normal and aberrant organ functions. Emerging spatial single-cell proteomic assays such as Image Mass Cytometry (IMC) and Co-Detection by Indexing (CODEX) have facilitated the study of cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e220f1154cf7270c3af5c7c5e4887abc
https://doi.org/10.1101/2023.01.15.524135
https://doi.org/10.1101/2023.01.15.524135
Publikováno v:
Diabetes care. 45(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad190b1e01fb46d4c19b4d1ec322625
https://pubmed.ncbi.nlm.nih.gov/36239401
https://pubmed.ncbi.nlm.nih.gov/36239401
Autor:
Andrew G. Cox, Diane C. Saunders, Peter B. Kelsey Jr., Allie A. Conway, Yevgenia Tesmenitsky, Julio F. Marchini, Kristin K. Brown, Jonathan S. Stamler, Dorothy B. Colagiovanni, Gary J. Rosenthal, Kevin J. Croce, Trista E. North, Wolfram Goessling
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 56-69 (2014)
Toxic liver injury is a leading cause of liver failure and death because of the organ’s inability to regenerate amidst massive cell death, and few therapeutic options exist. The mechanisms coordinating damage protection and repair are poorly unders
Externí odkaz:
https://doaj.org/article/b0dbc49cf4944575a2e417e636885493
Autor:
Han Zhu, Gaowei Wang, Kim-Vy Nguyen-Ngoc, Dongsu Kim, Michael Miller, Georgina Goss, Jenna Kovsky, Austin R. Harrington, Diane C. Saunders, Alexander L. Hopkirk, Rebecca Melton, Alvin C. Powers, Sebastian Preissl, Francesca M. Spagnoli, Kyle J. Gaulton, Maike Sander
Publikováno v:
Developmental Cell. 58:727-743.e11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc4f64272a5c56d3540c022c4a2f0bd
https://doi.org/10.1016/j.devcel.2023.03.011
https://doi.org/10.1016/j.devcel.2023.03.011