Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Diane C Cockrell"'
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 133-150 (2019)
Coxiella burnetii is an intracellular, gram-negative bacterium that causes the zoonosis Q fever. This disease typically presents as an acute flu-like illness with persistent, focalized infections occurring less frequently. Clinical outcomes of Q feve
Externí odkaz:
https://doaj.org/article/0b63355c05944c1da3202ca0fb4cdd54
Autor:
Diane C Cockrell, Carrie M Long, Shelly J Robertson, Jeffrey G Shannon, Heather E Miller, Lara Myers, Charles L Larson, Tregei Starr, Paul A Beare, Robert A Heinzen
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173528 (2017)
Published data show that murine bone marrow-derived macrophages (BMDM) restrict growth of avirulent phase II, but not virulent phase I, Coxiella burnetii. Growth restriction of phase II bacteria is thought to result from potentiated recognition of pa
Externí odkaz:
https://doaj.org/article/ae0a7409829b413bafafc49520a18c85
Autor:
Stacey D Gilk, Diane C Cockrell, Courtney Luterbach, Bryan Hansen, Leigh A Knodler, J Antonio Ibarra, Olivia Steele-Mortimer, Robert A Heinzen
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003107 (2013)
Reports implicating important roles for cholesterol and cholesterol-rich lipid rafts in host-pathogen interactions have largely employed sterol sequestering agents and biosynthesis inhibitors. Because the pleiotropic effects of these compounds can co
Externí odkaz:
https://doaj.org/article/58d2e455e4dc4a53adb01f82ccccfb9c
Autor:
Shaun Wachter, Diane C. Cockrell, Heather E. Miller, Kimmo Virtaneva, Kishore Kanakabandi, Benjamin Darwitz, Robert A. Heinzen, Paul A. Beare
Publikováno v:
Molecular microbiologyREFERENCES. 118(6)
Coxiella burnetii is the causative agent of Q fever. All C. burnetii isolates encode either an autonomously replicating plasmid (QpH1, QpDG, QpRS, or QpDV) or QpRS-like chromosomally integrated plasmid sequences. The role of the ORFs present in these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20436b59248c70f16f0b6e6e1ffb963a
https://pubmed.ncbi.nlm.nih.gov/36385554
https://pubmed.ncbi.nlm.nih.gov/36385554
Autor:
Shaun Wachter, Diane C Cockrell, Heather E Miller, Kimmo Virtaneva, Kishore Kanakabandi, Benjamin Darwitz, Robert A Heinzen, Paul A Beare
SummaryCoxiella burnetii is the causative agent of Q fever. All C. burnetii isolates encode either an autonomous replicating plasmid (QpH1, QpDG, QpRS, or QpDV) or QpRS-like chromosomally integrated plasmid sequences. The role of the ORFs present on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17d9b86fc30a0dec31e7146b52ad55a
https://doi.org/10.1101/2022.09.15.508156
https://doi.org/10.1101/2022.09.15.508156
Autor:
Carrie M. Long, Diane C. Cockrell, Mahelat Tesfamariam, Paul A. Beare, Jonathan Fintzi, Carl Shaia, Robert A. Heinzen
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C. burnetii WCV administration is associated with a der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28a078b7d9d93deb076600b066d2106
https://doi.org/10.1038/s41541-021-00296-6
https://doi.org/10.1038/s41541-021-00296-6
Autor:
Robert A. Heinzen, Daniel E. Sturdevant, Heather Miller, Diane C. Cockrell, Vinod Nair, Derek E. Moormeier, Paul A. Beare, Kelsi M. Sandoz
Publikováno v:
Journal of Bacteriology. 201
Coxiella burnetii, the etiological agent of Q fever, undergoes a unique biphasic developmental cycle where bacteria transition from a replicating (exponential-phase) large cell variant (LCV) form to a nonreplicating (stationary-phase) small cell vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc44bb2fec08ccabd2ec7ba7e341cee
https://doi.org/10.1128/jb.00009-19
https://doi.org/10.1128/jb.00009-19
Publikováno v:
mBio
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02816-18 (2019)
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02816-18 (2019)
Coxiella burnetii is an intracellular pathogenic bacterium that replicates within a lysosomal vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires effector proteins delivered into the host cell cytosol by the type 4B secretion system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc78939b64c886d918c7cddd69659207
https://pubmed.ncbi.nlm.nih.gov/30723133
https://pubmed.ncbi.nlm.nih.gov/30723133
Publikováno v:
Applied and Environmental Microbiology. 82:3042-3051
Host cell-free (axenic) culture of Coxiella burnetii in acidified citrate cysteine medium-2 (ACCM-2) has provided important opportunities for investigating the biology of this naturally obligate intracellular pathogen and enabled the development of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d727b24be1f2663cba969d7a23e9f5
https://doi.org/10.1128/aem.00261-16
https://doi.org/10.1128/aem.00261-16
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Microbiology
BMC Microbiology
Background Many gram-negative bacteria produce an outer membrane phospholipase A (PldA) that plays an important role in outer membrane function and is associated with virulence. Results In the current study, we characterized a pldA mutant of Coxiella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629240b4bde1245fa919dbdb8dcf56ac
https://doi.org/10.1186/s12866-018-1181-0
https://doi.org/10.1186/s12866-018-1181-0