Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Diane Abou"'
Autor:
Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E. Rodgers, Diane Abou, Valery Radchenko, Daniel L. J. Thorek
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Background 44Sc/47Sc is an attractive theranostic pair for targeted in vivo positron emission tomographic (PET) imaging and beta-particle treatment of cancer. The 44Ti/44Sc generator allows daily onsite production of this diagnostic isotope,
Externí odkaz:
https://doaj.org/article/0b81433194ff4a17b78c6f359d2e1aa6
Autor:
Hanwen Zhang, Diane Abou, Peng Lu, Abbie Meghan Hasson, Alexandria Villmer, Nadia Benabdallah, Wen Jiang, David Ulmert, Sean Carlin, Buck E. Rogers, Norman F. Turtle, Michael R. McDevitt, Brian Baumann, Brian W. Simons, Farrokh Dehdashti, Dong Zhou, Daniel L. J. Thorek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The growing interest and clinical translation of alpha particle (α) therapies brings with it new challenges to assess target cell engagement and to monitor therapeutic effect. Noninvasive imaging has great potential to guide α-treatment an
Externí odkaz:
https://doaj.org/article/9b792b047c414428bbbdfc607f1aa8a7
Autor:
Diane Abou, Nadia Benabdallah, Wen Jiang, Lu Peng, Hanwen Zhang, Alexandria Villmer, Mark S. Longtine, Daniel L. J. Thorek
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metastatic prostate cancer is incurable, and novel methods to detect the disease earlier and to direct definitive treatment are needed. Molecularly specific tools to localize diagnostic and cytotoxic radionuclide payloads to cancer cells and the surr
Externí odkaz:
https://doaj.org/article/8e08460ed5554000a202be14611b4501
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
S1. Hierarchical clustering based on Euclidean distance of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and untreated (C1-3) samples.S2. Multi-dimensional scaling plot of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1377f5f545ae64255126d352d870e4e0
https://doi.org/10.1158/1541-7786.22551840
https://doi.org/10.1158/1541-7786.22551840
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0445efa2285bf786789e370019ca125b
https://doi.org/10.1158/1541-7786.c.6534810
https://doi.org/10.1158/1541-7786.c.6534810
Autor:
Claire M. Storey, Mohamed Altai, Mesude Bicak, Darren R. Veach, Katharina Lückerath, Gabriel Adrian, Michael R. McDevitt, Teja Kalidindi, Julie E. Park, Ken Herrmann, Diane Abou, Wahed Zedan, Norbert Peekhaus, Robert J. Klein, Robert Damoiseaux, Steven M. Larson, Hans Lilja, Daniel Thorek, David Ulmert
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6220d4c184d7986fdc440382cf0a767f
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151575199
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151575199
Autor:
Nadia Benabdallah, William Scheve, Nicholas Dunn, Delynn Silvestros, Paul Schelker, Diane Abou, Uday Jammalamadaka, Richard Laforest, Zekun Li, Jonathan Liu, David H. Ballard, Nichole M. Maughan, Hiram Gay, Brian C. Baumann, Robert F. Hobbs, Buck Rogers, Amir Iravani, Abhinav K. Jha, Farrokh Dehdashti, Daniel L. J. Thorek
Publikováno v:
Theranostics
Rationale: Alpha particle emitting radiopharmaceuticals are generating considerable interest for the treatment of disseminated metastatic disease. Molecular imaging of the distribution of these agents is critical to safely and effectively maximize th
Autor:
Claire M Storey, Mohamed Altai, Mesude Bicak, Darren R Veach, Katharina Lückerath, Gabriel Adrian, Michael R McDevitt, Teja Kalidindi, Julie E Park, Ken Herrmann, Diane Abou, Wahed Zedan, Norbert Peekhaus, Robert J Klein, Robert Damoiseaux, Steven M Larson, Hans Lilja, Daniel Thorek, David Ulmert
External beam radiotherapy (EBRT) remains a common treatment for all stages of PCa, but DNA damage induced by EBRT upregulates androgen receptor (AR) pathway activity to promote therapeutic resistance. [89Zr]11B6-PET is a novel modality targeting pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b44b4f410b2a34affb530841fa9dac6f
https://doi.org/10.1101/2022.06.23.497290
https://doi.org/10.1101/2022.06.23.497290
Autor:
Mark S. Longtine, Ryan C. Riddle, David Ulmert, Lucy Summer, Jeff M. Michalski, Brian W. Simons, Amanda Fears, Nadia Benabdallah, Nicholas C. Zachos, Denise Chesner, Diane Abou, Michele Doucet, Daniel L.J. Thorek, Richard L. Wahl
Publikováno v:
Journal of Nuclear Medicine. 62:1751-1758
Background: Radium-223 dichloride ([223Ra]RaCl2) is the first approved alpha particle-emitting therapy and is indicated for treatment of bone metastatic castrate resistant prostate cancer. Approximately half of the dose is absorbed into the gastroint
Autor:
Diane Abou, Daniel L.J. Thorek, Andrew Rittenbach, Paige Finley, Benjamin M. W. Tsui, Ryan C. Riddle, David Ulmert, Ryan E. Tomlinson, Brian W. Simons, Abhinav K. Jha
Publikováno v:
Cancer Biother Radiopharm
Objective: Dose optimization and pharmacokinetic evaluation of α-particle emitting radium-223 dichloride ((223)RaCl(2)) by planar γ-camera or single photon emission computed tomography (SPECT) imaging are hampered by the low photon abundance and in