Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diane, Wengerodt"'
Publikováno v:
Cells, Vol 8, Iss 11, p 1446 (2019)
In contrast to the programmed nature of development, it is still a matter of debate whether aging is an adaptive and regulated process, or merely a consequence arising from a stochastic accumulation of harmful events that culminate in a global state
Externí odkaz:
https://doaj.org/article/2dd2afabe03e4ea7b920a2b2f05ab5d0
Autor:
Quratul, Ain, Christian W, Schmeer, Diane, Wengerodt, Yvonne, Hofmann, Otto W, Witte, Alexandra, Kretz
Publikováno v:
International journal of molecular sciences. 23(6)
Efficient purification of viable neural cells from the mature CNS has been historically challenging due to the heterogeneity of the inherent cell populations. Moreover, changes in cellular interconnections, membrane lipid and cholesterol compositions
Autor:
Emanuel, Barth, Akash, Srivastava, Diane, Wengerodt, Milan, Stojiljkovic, Hubertus, Axer, Otto W, Witte, Alexandra, Kretz, Manja, Marz
Publikováno v:
Aging (Albany NY)
The circadian clock system influences the biology of life by establishing circadian rhythms in organisms, tissues, and cells, thus regulating essential biological processes based on the day/night cycle. Circadian rhythms change over a lifetime due to
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2477, p 2477 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Still unresolved is the question of how a lifetime accumulation of somatic gene copy number alterations impact organ functionality and aging and age-related pathologies. Such an issue appears particularly relevant in the broadly post-mitotic central
Publikováno v:
Cells
Replicative senescence has initially been defined as a stress reaction of replication-competent cultured cells in vitro, resulting in an ultimate cell cycle arrest at preserved growth and viability. Classically, it has been linked to critical telomer