Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diane, Lefley"'
Autor:
Diane Lefley, Faith Howard, Fawaz Arshad, Steven Bradbury, Hannah Brown, Claudia Tulotta, Rachel Eyre, Denis Alférez, J. Mark Wilkinson, Ingunn Holen, Robert B. Clarke, Penelope Ottewell
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-21 (2019)
Abstract Background Late-stage breast cancer preferentially metastasises to bone; despite advances in targeted therapies, this condition remains incurable. The lack of clinically relevant models for studying breast cancer metastasis to a human bone m
Externí odkaz:
https://doaj.org/article/9c41d0f7f3c5497c955ee94df5a3474b
Autor:
Rachel Eyre, Denis G. Alférez, Angélica Santiago-Gómez, Kath Spence, James C. McConnell, Claire Hart, Bruno M. Simões, Diane Lefley, Claudia Tulotta, Joanna Storer, Austin Gurney, Noel Clarke, Mick Brown, Sacha J. Howell, Andrew H. Sims, Gillian Farnie, Penelope D. Ottewell, Robert B. Clarke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In breast cancer, dormant cancer cells may develop into bone metastases. Here, the authors demonstrate that microenvironmental IL1β stimulates metastatic breast cancer cell colonisation in the bone via IL1β-NFKB/CREB-Wnt pathway activation and canc
Externí odkaz:
https://doaj.org/article/c9b7748a363e46eb80d945fea7c4be66
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100899- (2021)
Externí odkaz:
https://doaj.org/article/ca1b6ab10af54442b16f395aa3b870ea
Autor:
Chris George, Diane Lefley, Victor Canuas-Landero, Claudia Tulotta, Hannah Corness, Caroline Wilson, Munitta Muthana, Penelope Ottewell
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101024- (2021)
Externí odkaz:
https://doaj.org/article/bf22d516ae584c6bba244fe08d277c77
Autor:
Simon, Akerman, Matthew, Fisher, Rachel A, Daniel, Diane, Lefley, Constantino C, Reyes-Aldasoro, Sarah Jane, Lunt, Sheila, Harris, Meit, Bjorndahl, Leigh J, Williams, Helen, Evans, Paul R, Barber, Vivien E, Prise, Borivoj, Vojnovic, Chryso, Kanthou, Gillian M, Tozer
Publikováno v:
International journal of cancer. 133(11)
Antiangiogenic therapy based on blocking the actions of vascular endothelial growth factor-A (VEGF) can lead to "normalization" of blood vessels in both animal and human tumors. Differential expression of VEGF isoforms affects tumor vascular maturity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf351737b1ed22a4818a35ca8672c196
https://pubmed.ncbi.nlm.nih.gov/23712501
https://pubmed.ncbi.nlm.nih.gov/23712501