Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Diane, Damotte"'
Autor:
Luca Simula, Mattia Fumagalli, Lene Vimeux, Irena Rajnpreht, Philippe Icard, Gary Birsen, Dongjie An, Frédéric Pendino, Adrien Rouault, Nadège Bercovici, Diane Damotte, Audrey Lupo-Mansuet, Marco Alifano, Marie-Clotilde Alves-Guerra, Emmanuel Donnadieu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The ability of CD8+ T cells to infiltrate solid tumors and reach cancer cells is associated with improved patient survival and responses to immunotherapy. Thus, identifying the factors controlling T cell migration in tumors is critical, so t
Externí odkaz:
https://doaj.org/article/643fa17256824db689f9eb5d26b03503
Autor:
Lucia Parlati, Mehdi Sakka, Aurelia Retbi, Samir Bouam, Lamia Hassani, Jean-François Meritet, Pierre Rufat, Dominique Bonnefont-Rousselot, Rui Batista, Benoit Terris, Agnès Bellanger, Dominique Thabut, Aurore Vozy, Jean-Philippe Spano, Romain Coriat, François Goldwasser, Selim Aractingi, Philippe Sogni, Stanislas Pol, Vincent Mallet, Jérôme Alexandre, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Sixtine De Percin, Nora Kramkimel, Olivier Huillard, Jeanne Chapron, Benedicte Deau-Fischer, Marie-Laure Brandely-Piat, Diane Damotte, Audrey Lupo, Marco Alifano, Marion Corouge, Clémence Hollande, Hélène Fontaine, Lorianne Lair Mehiri, Anaïs Vallet Pichard, Patrick Tilleul
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100880- (2023)
Background & Aims: There is concern about the burden of liver injury in patients with cancer exposed to immune checkpoints inhibitors (ICIs). Methods: In a retrospective cohort study, we evaluated the likelihood of grade 3/4 liver injury, of grade 3/
Externí odkaz:
https://doaj.org/article/788878b251bf4c95a2f7143042e64143
Autor:
Priyanka Devi-Marulkar, Solène Fastenackels, Pierre Karapentiantz, Jérémy Goc, Claire Germain, Hélène Kaplon, Samantha Knockaert, Daniel Olive, Marylou Panouillot, Pierre Validire, Diane Damotte, Marco Alifano, Juliette Murris, Sandrine Katsahian, Myriam Lawand, Marie-Caroline Dieu-Nosjean
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.
Externí odkaz:
https://doaj.org/article/6843b8158e4442199fa24d4eee02cf0d
Autor:
Julien Mazières, Diane Damotte, Virginie Westeel, Gérard Zalcman, Franck Morin, Marie-Ange Massiani, Jalal Assouad, Marie Wislez, Martine Antoine, Armelle Lavole, Olivier Carre, Thomas Egenod, Raffaele Caliandro, Catherine Dubos-Arvis, Gaelle Jeannin, Olivier Molinier, Alexandra Langlais, Francoise Le Pimpec Barthes, Laurent Brouchet, Bernard Milleron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background The IONESCO (IFCT-1601) trial assessed the feasibility of neoadjuvant durvalumab, for early-stage resectable non-small-cell lung cancer (NSCLC).Methods In a multicenter, single-arm, phase II trial, patients with IB (≥4 cm)-IIIA, non-N2,
Externí odkaz:
https://doaj.org/article/b39e97c95b144070ae7476897fa401e3
Autor:
Diane Damotte, Sarah Warren, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Audrey Mansuet-Lupo, Jérôme Biton, Hanane Ouakrim, Marco Alifano, Claire Gervais, Audrey Bellesoeur, Nora Kramkimel, Camille Tlemsani, Barbara Burroni, Angéline Duche, Franck Letourneur, Han Si, Rebecca Halpin, Todd Creasy, Ronald Herbst, Xing Ren, Pascale Morel, Alessandra Cesano, François Goldwasser, Karen Leroy
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients
Externí odkaz:
https://doaj.org/article/b75c5fd83d2d4639a48bed140c36dd2f
Autor:
Pascaline Boudou-Rouquette, Jennifer Arrondeau, Claire Gervais, Jean-Philippe Durand, Elizabeth Fabre, Sixtine De Percin, Clémentine Vaquin Villeminey, Anne-Catherine Piketty, Nathalie Rassy, Guillaume Ulmann, Diane Damotte, Audrey Mansuet-Lupo, Frédérique Giraud, Marco Alifano, Marie Wislez, Jérôme Alexandre, Anne Jouinot, François Goldwasser
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103630- (2021)
Background: Immune checkpoint inhibitors (ICI) are dramatically active in a minority of non-small cell lung cancer (NSCLC) patients. We studied here the relationship between patients's metabolism and outcome under ICI. Methods: Metastatic NSCLC patie
Externí odkaz:
https://doaj.org/article/c752ad522f9e41baab6f8929446462cf
Autor:
Elisabeth Ashton, Jennifer Arrondeau, Anne Jouinot, Pascaline Boudou-Rouquette, Laure Hirsch, Olivier Huillard, Guillaume Ulmann, Audrey Lupo-Mansuet, Diane Damotte, Marie Wislez, Marco Alifano, Jérôme Alexandre, François Goldwasser
Publikováno v:
Clinical Nutrition. 42:944-953
Autor:
Christophe Klein, Diane Damotte, Adrien Joseph, Sebastien Gouy, Marco Alifano, Marie-Caroline Dieu-Nosjean, Guido Kroemer, Eric Deutsch, Antoine Lafarge, Philippe Morice, Julien Adam, Patricia Pautier, Cyrus Chargari, Isabelle Cremer, Catherine Genestie, Pan Juncheng, Michele Mondini, Nizar Labaied, Mauro Loi, Valentina Astesana, Florine Obrist, Norma Bloy, Gautier Stoll, Nicolas Signolle, Judith Michels, Maria Castedo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Tumors rewire their metabolism to achieve robust anabolism and resistance against therapeutic interventions like cisplatin treatment. For example, a prolonged exposure to cisplatin causes downregulation of pyridoxal kinase (PDXK), the enzy
Externí odkaz:
https://doaj.org/article/23e58e9d7ee549c68bea1e307cd90c73
Autor:
Nicolas Alcala, Lise Mangiante, Nolwenn Le-Stang, Corinne E. Gustafson, Sandrine Boyault, Francesca Damiola, Karine Alcala, Marie Brevet, Françoise Thivolet-Bejui, Cécile Blanc-Fournier, Jean-Philippe Le Rochais, Gaëtane Planchard, Nathalie Rousseau, Diane Damotte, Jean Claude Pairon, Marie Christine Copin, Arnaud Scherpereel, Eric Wasielewski, Laurence Wicquart, Stéphanie Lacomme, Jean-Michel Vignaud, Gaspard Ancelin, Cécile Girard, Christine Sagan, Christelle Bonnetaud, Véronique Hofman, Paul Hofman, Jérôme Mouroux, Vincent Thomas de Montpreville, Estelle Clermont-Taranchon, Julien Mazieres, Isabelle Rouquette, Hugues Begueret, Jean-Yves Blay, Sylvie Lantuejoul, Raphael Bueno, Christophe Caux, Nicolas Girard, James D. McKay, Matthieu Foll, Françoise Galateau-Salle, Lynnette Fernandez-Cuesta
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 191-202 (2019)
Background: Malignant Pleural Mesothelioma (MPM) is an aggressive disease related to asbestos exposure, with no effective therapeutic options. Methods: We undertook unsupervised analyses of RNA-sequencing data of 284 MPMs, with no assumption of discr
Externí odkaz:
https://doaj.org/article/2c7c70f40fc542e08e13ea5e57802c71
Autor:
Alexandra Yannoutsos, Manon Fontaine, Alexandre Galloula, Diane Damotte, Gilles Chatellier, Patrizia Paterlini-Bréchot, Guy Meyer, Jean Pastre, Véronique Duchatelle, Valéria Marini, Karl-Léo Schwering, Isabelle Lazareth, Parinaz Ghaffari, Audrey Stansal, Hélène Sanson, Cécile Labrousse, Hélène Beaussier, Nesrine Ben Nasr, Marc Zins, Sergio Salmeron, Emmanuel Messas, Jean-Patrick Lajonchère, Joseph Emmerich, Pascal Priollet, Jean Trédaniel
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Smoking is a strong risk factor for cancer and atherosclerosis. Cancer mortality, especially from lung cancer, overtakes cardiovascular (CV) death rate in patients with peripheral arterial disease (PAD). Only a few patients with l
Externí odkaz:
https://doaj.org/article/60ccb455fccd4122946da8168a478308