Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Diana Zelencova"'
Autor:
Kalvis Brangulis, Inara Akopjana, Laura Drunka, Sofija Matisone, Diana Zelencova-Gopejenko, Shapla Bhattacharya, Janis Bogans, Kaspars Tars
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/87e8a34e17cd43af82b1eba9af0fab1e
Autor:
Diana Zelencova-Gopejenko, Aiga Grandane, Einars Loza, Daina Lola, Anda Sipola, Edgars Liepinsh, Pavel Arsenyan, Kristaps Jaudzems
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1723-1729
ε-Trimethyllysine dioxygenase (TMLD) is a non-heme Fe(II) and α-ketoglutarate dependent oxygenase that catalyzes the stereospecific hydroxylation of ε-trimethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c658d0aca97ae321a2e3fd6997debf
https://doi.org/10.1021/acsmedchemlett.2c00261
https://doi.org/10.1021/acsmedchemlett.2c00261
Autor:
Diana Zelencova-Gopejenko, Melita Videja, Aiga Grandane, Linda Pudnika-Okinčica, Anda Sipola, Karlis Vilks, Maija Dambrova, Kristaps Jaudzems, Edgars Liepinsh
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5528
Heart-type fatty-acid binding protein (FABP3) is an essential cytosolic lipid transport protein found in cardiomyocytes. FABP3 binds fatty acids (FAs) reversibly and with high affinity. Acylcarnitines (ACs) are an esterified form of FAs that play an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e76a363acf49ca4f9bb31e1cc8cf40
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:586-602
Aliphatic alkyl chain-containing 12–14-membered macrocycles have been designed as structural analogs of antimitotic natural product diazonamide A. Macrocycles were synthesized from 5-bromooxazole in 7 to 9 linear steps using Ru-catalyzed ring-closi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf9c073d229c1da3fbf929eb97ae312
https://doi.org/10.1007/s10593-020-02704-6
https://doi.org/10.1007/s10593-020-02704-6
Autor:
Raitis Bobrovs, Emils Edgars Basens, Laura Drunka, Iveta Kanepe, Sofija Matisone, Karlis Kristofers Velins, Victor Andrianov, Gundars Leitis, Diana Zelencova-Gopejenko, Dace Rasina, Aigars Jirgensons, Kristaps Jaudzems
Selectivity is a major issue in the development of drugs targeting pathogen aspartic proteases. Here we explore the selectivity determining factors by studying specifically designed malaria aspartic protease (plasmepsin) open-flap inhibitors. Metadyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f4309810a7ca4e781092097ce37d8e
https://doi.org/10.26434/chemrxiv-2022-hw0sn
https://doi.org/10.26434/chemrxiv-2022-hw0sn
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b222d798789acf5f59c5c5be7b707024
https://doi.org/10.3390/ecmc2021-11480
https://doi.org/10.3390/ecmc2021-11480
Publikováno v:
Proceedings of 6th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3680fa9a70cc611a3b98f746ed3994
https://doi.org/10.3390/ecmc2020-07485
https://doi.org/10.3390/ecmc2020-07485
Autor:
Irena Leite, Victor Andrianov, Diana Zelencova-Gopejenko, Einars Loza, Iveta Kazhoka-Lapsa, Ilona Domracheva, Marta Stojak, Stefan Chlopicki, Ivars Kalvins
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:1235-1235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8e0674d88befbf061f85fa9b43fa3d
https://doi.org/10.1007/s10593-021-03048-5
https://doi.org/10.1007/s10593-021-03048-5
Autor:
Inara Akopjana, Diana Zelencova, Ivars Petrovskis, Andris Kazaks, Kristaps Jaudzems, Atis Jekabsons, Kalvis Brangulis, Kaspars Tars
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1864:129499
Lyme disease is a tick-borne infection caused by Borrelia burgdorferi sensu lato complex spirochetes. The spirochete is located in the gut of the tick; as the infected tick starts the blood meal, the spirochete must travel through the hemolymph to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaa4b876a3e43a231b59d8702c73787
https://doi.org/10.1016/j.bbagen.2019.129499
https://doi.org/10.1016/j.bbagen.2019.129499
Autor:
Anna Czarna, Jinhua Wang, Diana Zelencova, Yao Liu, Xianming Deng, Hwan Geun Choi, Tinghu Zhang, Wenjun Zhou, Jae Won Chang, Hanne Kildalsen, Ole Morten Seternes, Nathanael S. Gray, Richard A. Engh, Ulli Rothweiler
Accepted manuscript version. Published version available at https://doi.org/10.1021/acs.jmedchem.7b01847. DYRK1A is one of five members of the dual-specificity tyrosine (Y) phosphorylation-regulated kinase (DYRK) family. The DYRK1A gene is located in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e522d8199e565018b19c4c440c9d9f1
https://hdl.handle.net/10037/14980
https://hdl.handle.net/10037/14980