Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diana Wider"'
Autor:
Samarpan Maiti, Kaushik Bhattacharya, Diana Wider, Dina Hany, Olesya Panasenko, Lilia Bernasconi, Nicolas Hulo, Didier Picard
Publikováno v:
eLife, Vol 12 (2023)
Cells are exposed to a wide variety of internal and external stresses. Although many studies have focused on cellular responses to acute and severe stresses, little is known about how cellular systems adapt to sublethal chronic stresses. Using mammal
Externí odkaz:
https://doaj.org/article/8dccfe64e7dd4eff8c8191177c079f57
Autor:
Kaushik Bhattacharya, Samarpan Maiti, Szabolcs Zahoran, Lorenz Weidenauer, Dina Hany, Diana Wider, Lilia Bernasconi, Manfredo Quadroni, Martine Collart, Didier Picard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The molecular chaperone Hsp90 decreases with age but whether organisms can physiologically tune expression is unclear. Here, the authors show that mammalian cells can adjust Hsp90 levels to accumulating cellular stress by translational reprogramming.
Externí odkaz:
https://doaj.org/article/98445de100014006b4ae943b041a9674
Autor:
Kaushik Bhattacharya, Lorenz Weidenauer, Tania Morán Luengo, Ellis C. Pieters, Pablo C. Echeverría, Lilia Bernasconi, Diana Wider, Yashar Sadian, Margreet B. Koopman, Matthieu Villemin, Christoph Bauer, Stefan G. D. Rüdiger, Manfredo Quadroni, Didier Picard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Hop, also known as Stip1 or Sti1, facilitates substrate transfer between the Hsp70 and Hsp90 molecular chaperones. Characterization of proteostasis-related pathways in STIP1 knock-out cell lines reveals that in eukaryotes Stip1 modulates the balance
Externí odkaz:
https://doaj.org/article/82875625c72b4d9c8c7eaaf0131c13bc
Autor:
Diana Wider, Didier Picard
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189403 (2017)
The availability of a wide range of reporter proteins, which can easily be quantitated, has had a major impact on many fields of biomedical research. In some experiments with tissue culture cells, it is necessary to control for differences in transfe
Externí odkaz:
https://doaj.org/article/6443458ba63c457a8d5d09c673a935c7
Autor:
Didier Picard, S. G. D. Rüdiger, Lorenz Weidenauer, Kaushik Bhattacharya, Diana Wider, Christoph Ruediger Bauer, Lilia Bernasconi, Pablo Christian Echeverria, Manfredo Quadroni, M. Villemin, T. Moran Luengo
SUMMARYHop/Stip1/Sti1 is thought to be essential as a co-chaperone to facilitate substrate transfer between the Hsp70 and Hsp90 molecular chaperones. Despite this proposed key function for protein folding and maturation, it is not essential in a numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c20ca7fec2711578ee7976a6564f6
Autor:
Didier Picard, Diana Wider
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189403 (2017)
PLOS ONE, Vol. 12, No 12 (2017) P. e0189403
PLoS ONE, Vol 12, Iss 12, p e0189403 (2017)
PLOS ONE, Vol. 12, No 12 (2017) P. e0189403
The availability of a wide range of reporter proteins, which can easily be quantitated, has had a major impact on many fields of biomedical research. In some experiments with tissue culture cells, it is necessary to control for differences in transfe
Autor:
Diana Wider, Didier Picard
This is a novel dual reporter assay for transfected tissue culture cells. It is based onthe naturally secreted luciferase from Gaussia princeps as the main reporter protein and a secreted version of the red fluorescent protein mCherry as internal sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f85ba379653787ed6c41ce113780b7
https://doi.org/10.17504/protocols.io.kbwcspe
https://doi.org/10.17504/protocols.io.kbwcspe