Výsledky vyhledávání - "Diana Whitaker"

Akademický článek

MiR-200c reprograms fibroblasts to recapitulate the phenotype of CAFs in breast cancer progression

Autor: Zhao Lin, Megan E. Roche, Víctor Díaz-Barros, Marina Domingo-Vidal, Diana Whitaker-Menezes, Madalina Tuluc, Guldeep Uppal, Jaime Caro, Joseph M. Curry, Ubaldo Martinez-Outschoorn

Publikováno v: Cell Stress, Vol 8, Pp 1-20 (2024)

Mesenchymal-epithelial plasticity driving cancer progression in cancer-associated fibroblasts (CAFs) is undetermined. This work identifies a subgroup of CAFs in human breast cancer exhibiting mesenchymal-to-epithelial transition (MET) or epithelial-l

Externí odkaz: https://doaj.org/article/0f8bc32797514971a5f36ac7b5b03a52

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Akademický článek

Macrophage and adipocyte interaction as a source of inflammation in kidney disease

Autor: Cristina Martos-Rus, Goni Katz-Greenberg, Zhao Lin, Eurico Serrano, Diana Whitaker-Menezes, Marina Domingo-Vidal, Megan Roche, Kavitha Ramaswamy, Douglas C. Hooper, Bonita Falkner, Maria P. Martinez Cantarin

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Abstract In obesity, adipose tissue derived inflammation is associated with unfavorable metabolic consequences. Uremic inflammation is prevalent and contributes to detrimental outcomes. However, the contribution of adipose tissue inflammation in urem

Externí odkaz: https://doaj.org/article/bc495e9753f94b0790517583f240a4d3

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Akademický článek

Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers

Autor: Marina Domingo-Vidal, Diana Whitaker-Menezes, Mehri Mollaee, Zhao Lin, Madalina Tuluc, Nancy Philp, Jennifer M. Johnson, Tingting Zhan, Joseph Curry, Ubaldo Martinez-Outschoorn

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

The most common cancers of the aerodigestive tract (ADT) are non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC). The tumor stroma plays an important role in ADT cancer development and progression, and contributes to

Externí odkaz: https://doaj.org/article/1a27894c72f64f59ae35937ec8c95bed

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Akademický článek

Metformin Clinical Trial in HPV+ and HPV– Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate

Autor: Joseph M. Curry, Jennifer Johnson, Mehri Mollaee, Patrick Tassone, Dev Amin, Alexander Knops, Diana Whitaker-Menezes, My G. Mahoney, Andrew South, Ulrich Rodeck, Tingting Zhan, Larry Harshyne, Nancy Philp, Adam Luginbuhl, David Cognetti, Madalina Tuluc, Ubaldo Martinez-Outschoorn

Publikováno v: Frontiers in Oncology, Vol 8 (2018)

Background: Metformin, an oral anti-hyperglycemic drug which inhibits mitochondrial complex I and oxidative phosphorylation has been reported to correlate with improved outcomes in head and neck squamous cell carcinoma (HNSCC) and other cancers. This

Externí odkaz: https://doaj.org/article/c9c4b795175a4c32b103ba961cafc5b2

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Akademický článek

Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer

Autor: Sara Bisetto, Diana Whitaker-Menezes, Nicole A. Wilski, Madalina Tuluc, Joseph Curry, Tingting Zhan, Christopher M. Snyder, Ubaldo E. Martinez-Outschoorn, Nancy J. Philp

Publikováno v: Frontiers in Oncology, Vol 8 (2018)

Head and neck squamous cell carcinoma (HNSCC) is the 6th most common human cancer and affects approximately 50,000 new patients every year in the US. The major risk factors for HNSCC are tobacco and alcohol consumption as well as oncogenic HPV infect

Externí odkaz: https://doaj.org/article/93e6d695bfd342e4b0f4ff53809ec104

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