Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Diana Teti"'
Autor:
Germana Lentini, Diana Teti, Isabella Venza, Francesco Stagno d'Alcontres, Mario Venza, Maria Visalli
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
In this review, we examine the multiple roles of ROS in the pathogenesis of melanoma, focusing on signal transduction and regulation of gene expression. In recent years, different studies have analyzed the dual role of ROS in regulating the redox sys
Autor:
Maria Visalli, Concetta Beninati, Mario Venza, Teresa Catalano, Isabella Venza, Diana Teti, Carmelo Biondo
Publikováno v:
Oncology Reports. 35:2451-2460
E-cadherin, a calcium-dependent cell-cell adhesion molecule, has an important role in epithelial cell function, maintenance of tissue architecture and cancer suppression. Loss of E-cadherin promotes tumor metastatic dissemination and predicts poor pr
Genistein, a natural isoflavone found in soybean products, is considered as a powerful anti-cancer agent, although the involved mechanisms are not fully understood. There is a growing body of evidence that, among the genes inhibited by genistein and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf3533e2aeedaeee577880969b06527
http://hdl.handle.net/11570/3128439
http://hdl.handle.net/11570/3128439
Autor:
Teresa Catalano, Carmelo Biondo, Diana Teti, Isabella Venza, Mario Venza, Concetta Beninati, Maria Visalli
Publikováno v:
Brain Tumor Pathology. 32:163-168
Epimutations are heritable and reversible cell markers, which can influence cell function going beyond the effects of DNA mutations. They result from multiple and coordinated mechanisms able to modulate gene expression. Regarding the significance of
Autor:
Maria Lentini, Carmelo Biondo, Maria Visalli, Teresa Catalano, Mario Venza, Diana Teti, Isabella Venza
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1849:247-256
Inactivation of p14ARF and p16INK4A by epigenetic changes in cutaneous and uveal melanoma has been here investigated. Compared with melanocytes, p14ARF mRNA reduction and p16INK4A inactivation were frequently noticed. No association between p14ARF pr
Autor:
Federica Agliano, Isabella Venza, Diana Teti, Maria Visalli, Rosaria Oteri, Mario Venza, Silvia Morabito, Carmelo Biondo
Publikováno v:
Toxicology in Vitro. 29:242-250
Cadmium (Cd) is a human carcinogen that likely acts via epigenetic mechanisms. However, the precise role of Cd in melanoma remains to be defined. The goals of this study are to: (i) examine the effect of Cd on the proliferation rate of cutaneous and
Autor:
Maria Visalli, Mario Venza, Federica Agliano, Carmelo Biondo, Silvia Morabito, Diana Teti, Rosaria Oteri, Gerardo Caruso, Maria Caffo, Isabella Venza
Publikováno v:
Current Genomics
Cadmium is a highly toxic heavy metal, which has a destroying impact on organs. Exposure to cadmium causes severe health problems to human beings due to its ubiquitous environmental presence and features of the pathologies associated with pro-longed
Epigenetic modifications can affect numerous mechanisms used by neoplastic cells to evade immune control. In melanoma epigenetic defects, caused by dysregulations in the expression of genome writers, erasers, or readers, play a significant role in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3c7b25512fe6a7af38a0c4aaa99a9a
http://hdl.handle.net/11570/3094560
http://hdl.handle.net/11570/3094560
Publikováno v:
Biochemical and Biophysical Research Communications. 440:551-557
We previously showed that Staphylococcus aureus and Pseudomonas aeruginosa stimulate IL-8 expression in human conjunctival epithelial cells through different signal transduction pathways. As in some cell types both the bacteria may induce the release
Publikováno v:
Pigment Cell & Melanoma Research. 26:193-204
Here, we explored the effects of the novel class II-specific histone deacetylase inhibitors (HDACis) MC1568 and MC1575 on interleukin-8 (IL-8) expression and cell proliferation in cutaneous melanoma cell line GR-M and uveal melanoma cell line OCM-3 u