Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diana Tabbaa"'
Autor:
Eliseo Papa, Michael Docktor, Christopher Smillie, Sarah Weber, Sarah P Preheim, Dirk Gevers, Georgia Giannoukos, Dawn Ciulla, Diana Tabbaa, Jay Ingram, David B Schauer, Doyle V Ward, Joshua R Korzenik, Ramnik J Xavier, Athos Bousvaros, Eric J Alm
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39242 (2012)
BACKGROUND:Pediatric inflammatory bowel disease (IBD) is challenging to diagnose because of the non-specificity of symptoms; an unequivocal diagnosis can only be made using colonoscopy, which clinicians are reluctant to recommend for children. Diagno
Externí odkaz:
https://doaj.org/article/dbee976b36a54737ac2c5bf0d90ea952
Autor:
Bei Hopkins, Steven J. Samuelsson, Terence Ta, Haiyan Jiang, Dawn Ciulla, Morgan L. Maeder, Joy E. Horng, Ari E. Friedland, Hoson Chao, Timothy Fennell, Georgia Giannoukos, Maxwell N. Skor, Sebastian Gloskowski, Christine D. Wilson, Rina Mepani, Diana Tabbaa, Gregory Gotta, Vic E. Myer, Jennifer A. DaSilva, Reshica Baral, Eugenio Marco, Alexandra Glucksmann, Deepak Reyon, Vidya Dhanapal, David Bumcrot, Luis A. Barrera, Shivangi Joshi, Tongyao Wang, Michael Stefanidakis, Abhishek Dass, Charles F Albright, Clifford Yudkoff, George S. Bounoutas, Scott Haskett, Shen Shen, Pam Stetkiewicz, Hariharan Jayaram
Publikováno v:
Nature Medicine. 25:229-233
Leber congenital amaurosis type 10 is a severe retinal dystrophy caused by mutations in the CEP290 gene1,2. We developed EDIT-101, a candidate genome-editing therapeutic, to remove the aberrant splice donor created by the IVS26 mutation in the CEP290
Autor:
Jason Cheng, Kevin Wasko, Nicholas Perry, Diana Tabbaa, Eugenio Marco, Georgia Giannoukos, Christopher Borges, Charles F. Albright
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 206(2)
Human regulatory T cells (Tregs) have been implicated in cancer immunotherapy and are also an emerging cellular therapeutic for the treatment of multiple indications. Although Treg stability during ex vivo culture has improved, methods to assess Treg
Autor:
Donna E. Leet, Atsushi Muraguchi, Donna Neuberg, Edward F. Fritsch, Ute E. Burkhardt, Christina Chen, Annabelle J. Anandappa, Wandi Zhang, Louise Williams, Oriol Olive, Diana Tabbaa, Zhuting Hu, Derin B. Keskin, Scott Steelman, Jintaek Kim, Kenneth J. Livak, Patrick A. Ott, Catherine J. Wu, Hiroyuki Kishi, Sachet A. Shukla, Jonathan Stevens, Indira Guleria, Jing Sun, Nir Hacohen, William J. Lane, David J. Bozym
Publikováno v:
Blood. 132(18)
Recent studies have highlighted the promise of targeting tumor neoantigens to generate potent antitumor immune responses and provide strong motivation for improving our understanding of antigen-T-cell receptor (TCR) interactions. Advances in single-c
Autor:
Mariko Forconi, Tereza Manousaki, Peter F. Stadler, Anna Maria Fausto, Simon D. M. White, Shigehiro Kuraku, Sumir Panji, Marcia Lara, Andreas Gnirke, Hervé Philippe, Shaohua Fan, Axel Meyer, Jean Nicolas Volff, Tsutomu Miyake, Sante Gnerre, Thorsten Burmester, Anne Nitsche, Igor Schneider, John J. Stegeman, Alison P. Lee, Kerstin Lindblad-Toh, Peter van Heusden, Chris T. Amemiya, Michael S. Campbell, Ettore Olmo, Vydianathan Ravi, Jason Turner-Maier, Denis Baurain, Gary W. Litman, Federica Di Palma, Nicolas Rohner, Manfred Schartl, Giuseppe Scapigliati, Oleg Simakov, Aaron M. Berlin, Barbara Picone, Ingo Braasch, Byrappa Venkatesh, David R. Nelson, Wilfried Haerty, Diana Tabbaa, M. Gail Mueller, Francesco Buonocore, Eric S. Lander, Gianluca De Moro, Uljana Hesse, Chris P. Ponting, Nathalie Feiner, Junaid Gamieldien, Clifford J. Tabin, Gregory L. Blatch, Tatsuya Ota, Steve Hoffmann, Maria Assunta Biscotti, John H. Postlethwait, Chris L. Organ, Jessica Alföldi, Lin Fan, Mark Robinson, Stephen M. J. Searle, Louise Williams, Mark E. Hahn, Sonja J. Prohaska, Jared V. Goldstone, Dariusz Przybylski, Iain MacCallum, Rosemary A. Dorrington, Joshua Z. Levin, Tatjana Sauka-Spengler, Kenta Sumiyama, Nil Ratan Saha, Henner Brinkmann, Jeremy Johnson, John P. Cannon, Filipe J. Ribeiro, Marco Gerdol, David B. Jaffe, Adriana Canapa, Hakim Tafer, Marco Barucca, Mark Yandell, Evan Mauceli, Alan Christoffels, Sibel I. Karchner, Adrienne L. Edkins, J. Joshua Smith, Bronwen Aken, Neil H. Shubin, Ted Sharpe, Domitille Chalopin, Alberto Pallavicini
Publikováno v:
Nature
Nature, Nature Publishing Group, 2013, 496 (7445), pp.311-316. ⟨10.1038/nature12027⟩
Nature 7445 (496), 311-316. (2013)
Nature, 2013, 496 (7445), pp.311-316. ⟨10.1038/nature12027⟩
ResearcherID
Nature, Nature Publishing Group, 2013, 496 (7445), pp.311-316. ⟨10.1038/nature12027⟩
Nature 7445 (496), 311-316. (2013)
Nature, 2013, 496 (7445), pp.311-316. ⟨10.1038/nature12027⟩
ResearcherID
Acquisition and storage of Latimeria chalumnae samples was supported by grants from the African Coelacanth Ecosystem Programme of the South African National Department of Science and Technology. Generation of the Latimeria chalumnae and Protopterus a
Autor:
Iain MacCallum, Ryan Hegarty, Brian Sogoloff, Laurie Holmes, David B. Jaffe, Eric S. Lander, Shuangye Yin, Bayo Lau, Chad Nusbaum, Ted Sharpe, Diana Tabbaa, Carsten Russ, Neil I. Weisenfeld, Louise Williams
Publikováno v:
Nature genetics
PMC
PMC
Complete knowledge of the genetic variation in individual human genomes is a crucial foundation for understanding the etiology of disease. Genetic variation is typically characterized by sequencing individual genomes and comparing reads to a referenc
Autor:
Charlie Albright, Sandra Teixeira, Jamaica Siwak, Abhishek Dass, Scott Haskett, Kiran Gogi, Diana Tabbaa, Eric L. Tillotson, Terence Ta, Fred Harbinski, Emily Brennan, Gregory Gotta, Ramya Viswanathan, Eugenio Marco, Hoson Chao, Frederick Ta, Deepak Reyon, Jen Da Silva, Meltem Isik, Kai-Hsin Chang, Edouard deDreuzy, Haiyan Jiang, Andrew Sadowski, Georgia Giannoukos, Katherine Loveluck, Tongyao Wang, Aditi Chalishazar, John A. Zuris, Abigail Vogelaar, Ari E. Friedland, Jack Heath, Chris Wilson, Minerva E. Sanchez
Publikováno v:
Blood. 132:409-409
Beta hemoglobinopathies resulting from dysfunctional or deficient adult beta-globin expression are some of the most prevalent inherited blood disorders in the world. Upregulation of developmentally-silenced fetal gamma-globin would replace adult beta
Autor:
Andreas Gnirke, Gad Getz, Sarah Young, Na Li, David B. Jaffe, Terrance Shea, Iain MacCallum, Louise Williams, Chad Nusbaum, Michael S. Lawrence, Aaron M. Berlin, Diana Tabbaa, Yotam Drier
Publikováno v:
Genome Research. 22:2241-2249
Eliminating the bacterial cloning step has been a major factor in the vastly improved efficiency of massively parallel sequencing approaches. However, this also has made it a technical challenge to produce the modern equivalent of the Fosmid- or BAC-
Autor:
Rosamond Rhodes, Asif T. Chinwalla, Tessa Madden, Ashlee M. Earl, Maria C. Rivera, Candace N. Farmer, Jonathan M. Goldberg, Karthik Kota, Victor Felix, Nicholas B. King, Shibu Yooseph, Erica Sodergren, Monika Bihan, Martin J. Blaser, Dirk Gevers, Dan Knights, Pamela Sankar, Anup Mahurkar, Heather Huot Creasy, Veena Bhonagiri, Thomas M. Schmidt, Curtis Huttenhower, Mina Rho, Todd J. Treangen, Thomas J. Sharpton, I. Min A. Chen, Bo Liu, Sarah K. Highlander, Catherine C. Davis, Susan M. Huse, Richard A. Gibbs, Noam J. Davidovics, Patricio S. La Rosa, Carsten Russ, Wesley C. Warren, Richard K. Wilson, Patrick Minx, Jean E. McEwen, Alyxandria M. Schubert, Scott Anderson, Bonnie P. Youmans, Jamison McCorrison, Kathie A. Mihindukulasuriya, Vandita Joshi, Peter J. Mannon, Brandi L. Cantarel, Joseph F. Petrosino, Jack D. Sobel, Chandri Yandava, Sharvari Gujja, Janet K. Jansson, David J. Dooling, Daniel McDonald, Rob Knight, Granger G. Sutton, Gary C. Armitage, Larry J. Forney, Robert S. Fulton, Yuan Qing Wu, Jonathan Crabtree, Susan Kinder-Haake, Lu Wang, Liang Ye, Victor M. Markowitz, Narmada Shenoy, Elizabeth A. Lobos, Ruth M. Farrell, Tatiana A. Vishnivetskaya, Patrick S. G. Chain, Jacques Ravel, Katherine H. Huang, Sergey Koren, Yan Ding, Christina Giblin, Jason R. Miller, Michelle G. Giglio, Gina A. Simone, Chad Nusbaum, Lynn M. Schriml, Matthew C. Ross, Daniel D. Sommer, Sandra L. Lee, Theresa A. Hepburn, Michael Holder, Shaila Chhibba, Patrick D. Schloss, Omry Koren, Lan Zhang, Catrina Fronick, Richard R. Sharp, Diana Tabbaa, Yuzhen Ye, Dennis C. Friedrich, Christie Kovar, Owen White, A. Scott Durkin, Michael Feldgarden, Gary L. Andersen, Makedonka Mitreva, Todd Wylie, Nihar U. Sheth, Sheila Fisher, John Martin, Jose C. Clemente, Xiang Qin, James Versalovic, Dana A. Busam, Bruce W. Birren, Jeremy Zucker, Yu-Hui Rogers, Shannon Dugan, Kristine M. Wylie, Katherine P. Lemon, Floyd E. Dewhirst, Nicola Segata, Konstantinos Liolios, Anthony A. Fodor, Elizabeth L. Appelbaum, Ramana Madupu, W. Michael Dunne, Katherine S. Pollard, Leslie Foster, Olukemi O. Abolude, Yue Liu, Nikos C. Kyrpides, Christopher Wellington, Yanjiao Zhou, Lita M. Proctor, Tsegahiwot Belachew, Mircea Podar, Julia A. Segre, Holli A. Hamilton, Aye Wollam, Paul Spicer, Lei Chen, Sarah Young, Beltran Rodriguez-Mueller, Todd Z. DeSantis, Sean M. Sykes, Toby Bloom, Kelvin Li, Shane Canon, Catherine Jordan, Manolito Torralba, Brandi Herter, R. Dwayne Lunsford, Krishna Palaniappan, Jeroen Raes, Hongyu Gao, Barbara A. Methé, Kjersti Aagaard, Amy L. McGuire, Jonathan Friedman, Matthew D. Pearson, Jason Walker, Mary A. Cutting, Jonathan H. Badger, Diane E. Hoffmann, Tulin Ayvaz, Michael Fitzgerald, Brian J. Haas, Ravi Sanka, Doyle V. Ward, Kris A. Wetterstrand, Mark A. Watson, Christopher Smillie, Lucinda Fulton, Zhengyuan Wang, Lisa Begg, James R. White, Konstantinos Mavrommatis, Lucia Alvarado, Pamela McInnes, Emily L. Harris, Harindra Arachchi, Craig Pohl, Catherine A. Lozupone, Ruth E. Ley, Clinton Howarth, Yiming Zhu, Huaiyang Jiang, Gregory A. Buck, Carl C. Baker, Kimberley D. Delehaunty, Cristyn Kells, Katarzyna Wilczek-Boney, Kim C. Worley, Cesar Arze, J. Fah Sathirapongsasuti, Carolyn Deal, Sandra W. Clifton, Ken Chu, Rachel L. Erlich, Elaine R. Mardis, Cecil M. Lewis, Niall Lennon, Margaret Priest, Scott T. Kelley, Kymberlie Hallsworth-Pepin, Jane Peterson, Allison D. Griggs, Michelle O'Laughlin, Heidi H. Kong, Joshua Orvis, Maria Y. Giovanni, Sahar Abubucker, Dawn Ciulla, Sean Conlan, Chien Chi Lo, Antonio Gonzalez, Georgia Giannoukos, Jennifer R. Wortman, Paul Brooks, Jacques Izard, Chad Tomlinson, Donna M. Muzny, Shital M. Patel, Eric J. Alm, George M. Weinstock, Irene Newsham, Jeffrey G. Reid, Karoline Faust, Qiandong Zeng, Elena Deych, Nathalia Garcia, Mathangi Thiagarajan, James A. Katancik, Vivien Bonazzi, Robert C. Edgar, Christian J. Buhay, Indresh Singh, Johannes B. Goll, Ioanna Pagani, Vincent Magrini, Wendy A. Keitel, Emma Allen-Vercoe, Teena Mehta, Jeffery A. Schloss, William D. Shannon, Mihai Pop, Matthew B. Scholz, Valentina Di Francesco, Rebecca Truty, Karen E. Nelson, Kevin Riehle, Lora Lewis, Joseph L. Campbell, Laurie Zoloth
Publikováno v:
Nature
PubMed Central
PubMed Central
A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has establishe
Autor:
Michael Feldgarden, Shibu Yooseph, Divya Kalra, Theresa A. Hepburn, Navjeet Singh, Richard A. Gibbs, Shawn Leonard, Richard K. Wilson, Elizabeth L. Appelbaum, Niall J. Lennon, Hongyu Gao, Kathie A. Mihindukulasuriya, Bonnie P. Youmans, Lynn K. Carmichael, Yue Shang, Xiang Qin, Ashlee M. Earl, George M. Weinstock, Candace N. Farmer, Scott Anderson, Yu Hui A. Rogers, Erica Sodergren, Otis Hall, Georgia Giannoukos, Joseph F. Petrosino, Brian J. Haas, Todd Z. DeSantis, Kim C. Worley, Michelle O'Laughlin, Craig Pohl, Dawn Ciulla, Matthew C. Ross, Bruce W. Birren, Patrick D. Schloss, Rachel L. Erlich, Lucinda Fulton, Yanjiao Zhou, David J. Dooling, Toby Bloom, Donna M. Muzny, Katarzyna Wilczek-Boney, Leigh Aird, Sarah K. Highlander, Kelvin Li, Elaine R. Mardis, Dirk Gevers, Doyle V. Ward, Vincent Magrini, Keenan Ross, Vandita Joshi, Tulin Ayvaz, John Gill, Christie Kovar, Diana Tabbaa, Susanna Hamilton, Karen E. Nelson, Lora Lewis, Robert S. Fulton, Lisa Hemphill, Jonathan Crabtree, Cesar Arze, Jennifer R. Wortman, Barbara A. Methé, Cristyn Kells, Edward A. Belter, Laura Courtney, Monika Bihan
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39315 (2012)
PLoS ONE
PLoS ONE
The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples. To characterize these samples, the partic