Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Diana S. Woodruff-Pak"'
Autor:
John A. Kennard, Diana S. Woodruff-Pak
Publikováno v:
Frontiers in Aging Neuroscience, Vol 3 (2011)
Knowledge of age sensitivity, the capacity of a behavioral test to reliably detect age-related changes, has utility in the design of experiments to elucidate processes of normal aging. We review the application of these tests in studies of normal agi
Externí odkaz:
https://doaj.org/article/ec6a9f11799c4db485cda95f234157d0
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 4 (2010)
Nicotinic acetylcholine receptors (nAChRs) are essentially involved in learning and memory. A neurobiologically and behaviorally well-characterized measure of learning and memory, eyeblink classical conditioning, is sensitive to disruptions in acetyl
Externí odkaz:
https://doaj.org/article/616d2b3b695a4d818c3088d1802c00b6
Autor:
James O. Mudd, Corrine Y. Jurgens, Jennifer K. Green, Christopher S. Lee, Jill M. Gelow, Julie T. Bidwell, Diana S. Woodruff-Pak
Publikováno v:
Journal of Cardiovascular Nursing. 28:534-540
Introduction: Mild cognitive dysfunction is common among adults with heart failure (HF). We hypothesized that mild cognitive dysfunction would be associated with poor HF self-care behaviors, particularly patients’ ability to respond to symptoms. Me
Autor:
John A. Kennard, Diana S. Woodruff-Pak
Publikováno v:
Physiology & Behavior. 106:423-427
In this study we compared two types of forced exercise—a low impact paradigm to minimize stress, which included speeds up to 10 m/min and a stressful high impact paradigm, with speeds up to 21 m/min. 150 male C57BL/6J mice were randomly assigned to
Publikováno v:
Drug Delivery Letters. 2:14-21
Autor:
Jacob Raber, Diana S. Woodruff-Pak
Publikováno v:
Current Translational Geriatrics and Experimental Gerontology Reports. 1:1-10
Slow decline in cognition is key to the clinical diagnosis of Alzheimer’s disease (AD). This diagnosis relies on screening tests insensitive to detection of prodromal AD, which occurs years before the appearance of clinical symptoms. Neuroscience-b
Publikováno v:
Behavioural Brain Research. 225:290-296
The context preexposure facilitation effect (CPFE) is an elaboration of contextual fear conditioning and refers to enhanced contextual conditioning resulting from preexposure to the context prior to a separate, brief context-shock episode. A version
Autor:
Kevin L. Brown, Diana S. Woodruff-Pak
Publikováno v:
Developmental Psychobiology. 54:423-432
Eyeblink classical conditioning in pre-weanling rabbits was examined in the present study. Using a custom lightweight headpiece and restrainer, New Zealand white littermates were trained once daily in 400 ms delay eyeblink classical conditioning from
Autor:
Garnik G. Akopian, Ka Hung Lee, Alexis Agelan, Kim Phuong Thi Nguyen, Diana S. Woodruff-Pak, Michael R. Foy, Jordan Zach, John A. Kennard, Richard F. Thompson, David M. Comalli
Publikováno v:
Proceedings of the National Academy of Sciences. 107:1624-1629
Cognitive functions show many alternative outcomes and great individual variation during normal aging. We examined learning over the adult life span in CBA mice, along with morphological and electrophysiological substrates. Our aim was to compare cer
Autor:
Diana S. Woodruff-Pak
Publikováno v:
Journal of Alzheimer's Disease. 15:507-521
This Special Issue of the Journal of Alzheimer's Disease (JAD) provides an overview of animal models of Alzheimer's disease (AD). Very few species spontaneously develop the cognitive, behavioral, and neuropathological symptoms of AD, yet AD research