Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Diana S. Korshunova"'
Autor:
Marina V. Kubekina, Yulia Yu. Silaeva, Alexandra V. Bruter, Diana S. Korshunova, Leonid A. Ilchuk, Yulia D. Okulova, Mariya O. Soldatova, Evgeniya Seryogina, Inga M. Kolesnik, Polina A. Ukolova, Mikhail V. Korokin, Alexey V. Deykin
Publikováno v:
Research Results in Pharmacology, Vol 7, Iss 3, Pp 33-39 (2021)
Introduction: PolG-alpha is a nuclear-encoded enzyme which provides replication and repair of mitochondrial DNA. D257A mutation of PolG-alpha leads to change in the N-terminal ”proofreading” domain, which deprives the enzyme of 3′-5′ exonucle
Externí odkaz:
https://doaj.org/article/2f3fb4bdef8948059ade8b9c4c2824c0
Autor:
Olesya A. Puchenkova, Sergey V. Nadezhdin, Vladislav O. Soldatov, Maxim A. Zhuchenko, Diana S. Korshunova, Marina V. Kubekina, Evgeny N. Korshunov, Liliya V. Korokina, Polina A. Golubinskaya, Aleksandr L. Kulikov, Vladimir V. Gureev, Vladimir M. Pokrovskiy, Evgeniy A. Patrakhanov, Petr R. Lebedev, Tatyana A. Denisyuk, Veronika S. Belyaeva, Evgeniya A. Movchan, Elizaveta I. Lepetukha, Mikhail V. Pokrovskiy
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 8, Iss 2, Pp 100-111 (2020)
Introduction. The drugs affecting a mitochondrial dysfunction, oxidative stresses, apoptosis and inflammation of the vascular wall, have a high potential for the prevention and treatment of atherosclerotic lesions. In this regard, the use of EPOR/CD1
Externí odkaz:
https://doaj.org/article/18dd05f9bdca4af793634b3a2bc51138
Autor:
Tatiana V. Egorova, Ivan I. Galkin, Oleg A. Velyaev, Svetlana G. Vassilieva, Irina M. Savchenko, Vyacheslav A. Loginov, Marina A. Dzhenkova, Diana S. Korshunova, Olga S. Kozlova, Dmitry N. Ivankov, Anna V. Polikarpova
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9117
Mutations that prevent the production of proteins in the DMD gene cause Duchenne muscular dystrophy. Most frequently, these are deletions leading to reading-frame shift. The “reading-frame rule” states that deletions that preserve ORF result in a
Autor:
Alexandra V. Bruter, Yulia D. Okulova, Diana S. Korshunova, M. V. Korokin, Yulia Yu. Silaeva, Inga M. Kolesnik, Leonid A. Ilchuk, Mariya O. Soldatova, Marina V. Kubekina, Polina A. Ukolova, Alexey V. Deykin, Evgeniya Seryogina
Publikováno v:
Research Results in Pharmacology, Vol 7, Iss 3, Pp 33-39 (2021)
Research Results in Pharmacology 7(3): 33-39
Research Results in Pharmacology 7(3): 33-39
Introduction: PolG-alpha is a nuclear-encoded enzyme which provides replication and repair of mitochondrial DNA. D257A mutation of PolG-alpha leads to change in the N-terminal ”proofreading” domain, which deprives the enzyme of 3′-5′ exonucle
Autor:
Alexandra V. Bruter, Leonid A. Ilchuk, Eugenii N. Korshunov, Diana S. Korshunova, Alexey V. Deykin, Y.Y. Silaeva, A A Kalinina, Vladislav O. Soldatov, Petr V. Sergiev, Marina V. Kubekina
Publikováno v:
Transgenic Research
Graphic abstract The current coronavirus disease (COVID-19) pandemic remains one of the most serious public health problems. Increasing evidence shows that infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes a very comple
Autor:
Vladic Mogila, Alexandra A. Bruter, Ekaterina A. Varlamova, Diana S. Korshunova, Victor V. Tatarskiy, Aleksander A. Shtil, Igor B. Roninson
Publikováno v:
Cancer Research. 82:6003-6003
CDK8 and CDK19 are two paralogous kinases of transcription-regulating Mediator complex, which mediate transcriptional reprogramming by potentiating the induction of previously silent genes that are activated by different signal-responsive transcripti
Autor:
Diana S. Korshunova, Marina V. Kubekina, Evgeniy Korshunov, Nikolay Lukyanov, Pavel A Kusov, Maria Yablonskaia, Y.Y. Silaeva, V A Kalmykov, Alexey V. Deykin
Publikováno v:
Research Results in Pharmacology, Vol 4, Iss 4, Pp 115-122 (2018)
Research Results in Pharmacology 4(4): 115-122
Research Results in Pharmacology 4(4): 115-122
Introduction: Lesch-Nyhan syndrome is a clinical and laboratory disorder caused by X-linked disruption of the purine metabolism. The deletion in the HPRT1 gene leads to the disappearance of valine in the eighth position of the protein amino acid sequ
Autor:
E N Korshunov, Diana S. Korshunova, V A Kalmykov, Igor B. Roninson, Y.Y. Silaeva, Alexander A. Shtil, E A Varlamova, Alexey V. Deykin, Marina V. Kubekina
Publikováno v:
Doklady. Biochemistry and biophysics. 490(1)
CDK8-mediated transcriptional reprogramming is essential for an extensive gene expression. Constitutive knockouts of the cdk8 gene are lethal at the morula stage. For modeling transcriptional reprogramming in an adult organism, we investigated the po