Pharmacology of antihistamines

Autor: Martin K Church, Diana S Church

Publikováno v: Indian Journal of Dermatology, Vol 58, Iss 3, Pp 219-224 (2013)

H 1- antihistamines, the mainstay of treatment for urticaria, were developed from anticholinergic drugs more than 70 years ago. They act as inverse agonists rather than antagonists of histamine H 1 -receptors which are members of the G-protein family

Externí odkaz: https://doaj.org/article/b4fc608ddce8481d9eccefc5b2292a77

Pharmacology of Antihistamines

Autor: Martin K. Church, Diana S. Church

Publikováno v: World Allergy Organization Journal, Vol 4, Iss, Pp S22-S27 (2011)
Indian Journal of Dermatology
The World Allergy Organization Journal
Indian Journal of Dermatology, Vol 58, Iss 3, Pp 219-224 (2013)

This article reviews the molecular biology of the interaction of histamine with its H1-receptor and describes the concept that H1-antihistamines are not receptor antagonists but are inverse agonists i.e. they produce the opposite effect on the recept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df7aec0a06f9b39518452f0e01c9353
https://doi.org/10.1097/wox.0b013e3181f385d9

Allergic Rhinitis and Conjunctivitis: Update on Pathophysiology

Autor: James I. McGill, Ruby Pawankar, Jean-Baptiste Watelet, Martin K. Church, Diana S. Church

Publikováno v: Allergy Frontiers: Clinical Manifestations ISBN: 9784431883166

Our understanding of the development and mechanism(s) of allergic diseases has changed dramatically over the last 20 years. With the advent of genetic studies it has now become clear that the linear model, as defined by the allergic march, is no long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f0dc30644330a3b7111cdd4ad8dbf0b
https://doi.org/10.1007/978-4-431-88317-3_1