Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Diana Risin"'
Autor:
Mamta J. Patel, Semyon A. Risin, Hanjoong Jo, Diana Risin, Michelle C. Sykes, Wenbin Liu, Nancy E. Ward
Publikováno v:
Journal of Cellular Biochemistry. 101:587-599
Weightlessness or microgravity of spaceflight induces bone loss due in part to decreased bone formation by unknown mechanisms. Due to difficulty in performing experiments in space, several ground-based simulators such as the Rotating Wall Vessel (RWV
Publikováno v:
Microgravity - Science and Technology. 18:243-246
Space flights result in remarkable effects on various physiological systems, including a decline in cellular immune functions. Previous studies have shown that exposure to microgravity, both true and modeled, can cause significant changes in numerous
Publikováno v:
Journal of Cellular Biochemistry. 99:1187-1202
Studies conducted in real Space and in ground-based microgravity analog systems (MAS) have demonstrated changes in numerous lymphocyte functions. In this investigation we explored whether the observed functional changes in lymphocytes in MAS are asso
Publikováno v:
Journal of Applied Physiology. 96:2028-2033
In long-term space travel, the crew is exposed to microgravity and radiation that invoke potential hazards to the immune system. T cell activation is a critical step in the immune response. Receptor-mediated signaling is inhibited in both microgravit
Autor:
Boris Yoffe, Vladimir I. Khaoustov, Bhuvaneswari Krishnan, Humberto E. Soriano, Diana Risin, Gretchen J. Darlington, Neal R. Pellis
Publikováno v:
Advances in Space Research. 24:829-836
We used microgravity-simulated bioreactors that create the unique environment of low shear force and high-mass transfer to establish long-term cultures of primary human liver cells (HLC). To assess the feasibility of establishing HLC cultures, human
Autor:
Diana Risin, Thomas J. Goodwin, Bradley W. McIntyre, Roland P. Pizzini, Tacey L. Baker, Neal R. Pellis, David Cooper, Glenn F. Spaulding
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 33:398-405
Immunity relies on the circulation of lymphocytes through many different tissues including blood vessels, lymphatic channels, and lymphoid organs. The ability of lymphocytes to traverse the interstitium in both nonlymphoid and lymphoid tissues can be
Autor:
Diana Risin, Mamta Patel Nagaraja
Publikováno v:
Journal of cellular biochemistry. 114(5)
Bone loss is a well documented phenomenon occurring in humans both in short- and in long-term spaceflights. This phenomenon can be also reproduced on the ground in human and animals and also modeled in cell-based analogs. Since space flights are infr
Autor:
Yasuiki Umezu, Diana Risin, Roland P. Pizzini, Charles M. Balch, Neal R. Pellis, Eugenie S. Kleinerman
Publikováno v:
Cancer Immunology Immunotherapy. 40:57-64
The ability of the lymphocytes to move through the interstitium is obligatory to the immune response. We previously showed that tumor-infiltrating lymphocytes (TIL) from human melanoma and renal cell carcinoma demonstrate a dramatic decrease in their
Publikováno v:
Cancer. 71:2833-2837
BACKGROUND Locomotion of peripheral blood lymphocytes (PBL) through peritumoral matrix is obligatory for tumor cell killing. The authors investigated the effect of surgery on lymphocyte locomotion and compared it with the effect on natural killer cel
Publikováno v:
Journal of Immunological Methods. 157:175-180
There is an increased application of three-dimensional type I rat tail collagen as an in vitro model for the peritumoral matrix in analysis of lymphocyte migration. The increased demand prompted us to modify the previous methods. We here describe our